Matches in SemOpenAlex for { <https://semopenalex.org/work/W2013739234> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2013739234 endingPage "207" @default.
- W2013739234 startingPage "198" @default.
- W2013739234 abstract "The use of interleukin 2-based immunotherapies for cancer has been associated with significant resonses in tumor models in both mouse and humans. Further definition of the elements responsible for response is now possible. It appears that the respnse is associated with T-cell infiltration of the tumor, and transfer of tumor-infiltrating lymphocytes expanded in tissue culture with interleukin 2 is associated with significant antitumor effects. Further expansion of cultured human melanoma tumor-infiltrating lymphocytes with suppression of lymphokine-activated killer activity as well as the modulation of monocyte activity by interleukin 4 suggests that this cytokine may be clinically useful alone or in combination with interleukin 2. Other means of enhancing the activity of interleukin 2-based immunotheraphy are suggested by the finding that tumor cell susceptibility to lysis by natural killer cells is depressed following treatment with interferon γ and tumor necrosis factor, but susceptibility to lysis by tumor-infiltrating lymphocytes is markedly enhanced. Further development of these therapies will require innovative interpretation and application of findings related to the processing and presentation of human tumor antigens and the nature of tumor antigens and careful analysis of they T-cell receptor in antitumor effectors." @default.
- W2013739234 created "2016-06-24" @default.
- W2013739234 creator A5008892129 @default.
- W2013739234 creator A5024528047 @default.
- W2013739234 creator A5039197753 @default.
- W2013739234 creator A5041829661 @default.
- W2013739234 creator A5055290282 @default.
- W2013739234 creator A5072133376 @default.
- W2013739234 date "1990-06-01" @default.
- W2013739234 modified "2023-09-27" @default.
- W2013739234 title "Mechanisms of immunologic antitumor therapy: lessons from the laboratory and clinical applications" @default.
- W2013739234 cites W1884121283 @default.
- W2013739234 cites W1965861552 @default.
- W2013739234 cites W1975568557 @default.
- W2013739234 cites W2061227314 @default.
- W2013739234 cites W2065774100 @default.
- W2013739234 cites W2089828715 @default.
- W2013739234 cites W2105054548 @default.
- W2013739234 cites W2106135817 @default.
- W2013739234 cites W2173411263 @default.
- W2013739234 cites W2255455702 @default.
- W2013739234 cites W2322553446 @default.
- W2013739234 cites W2335365056 @default.
- W2013739234 cites W2336865510 @default.
- W2013739234 cites W2411128694 @default.
- W2013739234 cites W42013536 @default.
- W2013739234 cites W4233277662 @default.
- W2013739234 doi "https://doi.org/10.1016/0198-8859(90)90020-p" @default.
- W2013739234 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2190952" @default.
- W2013739234 hasPublicationYear "1990" @default.
- W2013739234 type Work @default.
- W2013739234 sameAs 2013739234 @default.
- W2013739234 citedByCount "26" @default.
- W2013739234 countsByYear W20137392342013 @default.
- W2013739234 countsByYear W20137392342021 @default.
- W2013739234 crossrefType "journal-article" @default.
- W2013739234 hasAuthorship W2013739234A5008892129 @default.
- W2013739234 hasAuthorship W2013739234A5024528047 @default.
- W2013739234 hasAuthorship W2013739234A5039197753 @default.
- W2013739234 hasAuthorship W2013739234A5041829661 @default.
- W2013739234 hasAuthorship W2013739234A5055290282 @default.
- W2013739234 hasAuthorship W2013739234A5072133376 @default.
- W2013739234 hasConcept C129374314 @default.
- W2013739234 hasConcept C147483822 @default.
- W2013739234 hasConcept C17991360 @default.
- W2013739234 hasConcept C203014093 @default.
- W2013739234 hasConcept C2776090121 @default.
- W2013739234 hasConcept C2777371288 @default.
- W2013739234 hasConcept C2777701055 @default.
- W2013739234 hasConcept C2778326572 @default.
- W2013739234 hasConcept C2778690821 @default.
- W2013739234 hasConcept C28651165 @default.
- W2013739234 hasConcept C3020616263 @default.
- W2013739234 hasConcept C49382859 @default.
- W2013739234 hasConcept C502942594 @default.
- W2013739234 hasConcept C70905583 @default.
- W2013739234 hasConcept C71924100 @default.
- W2013739234 hasConcept C74172505 @default.
- W2013739234 hasConcept C86803240 @default.
- W2013739234 hasConcept C8891405 @default.
- W2013739234 hasConceptScore W2013739234C129374314 @default.
- W2013739234 hasConceptScore W2013739234C147483822 @default.
- W2013739234 hasConceptScore W2013739234C17991360 @default.
- W2013739234 hasConceptScore W2013739234C203014093 @default.
- W2013739234 hasConceptScore W2013739234C2776090121 @default.
- W2013739234 hasConceptScore W2013739234C2777371288 @default.
- W2013739234 hasConceptScore W2013739234C2777701055 @default.
- W2013739234 hasConceptScore W2013739234C2778326572 @default.
- W2013739234 hasConceptScore W2013739234C2778690821 @default.
- W2013739234 hasConceptScore W2013739234C28651165 @default.
- W2013739234 hasConceptScore W2013739234C3020616263 @default.
- W2013739234 hasConceptScore W2013739234C49382859 @default.
- W2013739234 hasConceptScore W2013739234C502942594 @default.
- W2013739234 hasConceptScore W2013739234C70905583 @default.
- W2013739234 hasConceptScore W2013739234C71924100 @default.
- W2013739234 hasConceptScore W2013739234C74172505 @default.
- W2013739234 hasConceptScore W2013739234C86803240 @default.
- W2013739234 hasConceptScore W2013739234C8891405 @default.
- W2013739234 hasIssue "2" @default.
- W2013739234 hasLocation W20137392341 @default.
- W2013739234 hasLocation W20137392342 @default.
- W2013739234 hasOpenAccess W2013739234 @default.
- W2013739234 hasPrimaryLocation W20137392341 @default.
- W2013739234 hasRelatedWork W141870358 @default.
- W2013739234 hasRelatedWork W1986580574 @default.
- W2013739234 hasRelatedWork W2013270686 @default.
- W2013739234 hasRelatedWork W2013739234 @default.
- W2013739234 hasRelatedWork W2103739833 @default.
- W2013739234 hasRelatedWork W2395972455 @default.
- W2013739234 hasRelatedWork W2410875093 @default.
- W2013739234 hasRelatedWork W414866421 @default.
- W2013739234 hasRelatedWork W4300483635 @default.
- W2013739234 hasRelatedWork W2413861156 @default.
- W2013739234 hasVolume "28" @default.
- W2013739234 isParatext "false" @default.
- W2013739234 isRetracted "false" @default.
- W2013739234 magId "2013739234" @default.
- W2013739234 workType "article" @default.