FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2013749215> ?p ?o ?g. }

• W2013749215 endingPage "3024" @default.
• W2013749215 startingPage "3009" @default.
• W2013749215 abstract "We investigated the effect of administration of docosahexaenoic acid (C22:6, n-3; 300 mg/kg.day, for 12 weeks) on the degree of membrane order and membrane-bound acetylcholinesterase activity of the cerebral cortex synaptic plasma membrane in male Wistar rats. Docosahexaenoic acid levels in the synaptic plasma membrane increased significantly by 16% over levels in control rats concomitant with an increase in the molar ratio of docosahexaenoic acid to arachidonic acid. Synaptic plasma membrane order, assessed by 1,6-diphenyl-1,3,5-hexatriene, which measures order of the bulk internal hydrophobic lipid core, decreased significantly in the docosahexaenoic acid-fed rats. Lateral mobility of both global and annular lipids measured by pyrene also increased. Acetylcholinesterase activity of the synaptic plasma membrane was unaffected, and synaptic plasma membrane phospholipid contents increased in the docosahexaenoic acid-fed rats, with a concomitant decrease in the cholesterol/phospholipid molar ratio. Lipid peroxide and reactive oxygen species, indicators of tissue oxidative stress, decreased in both the cerebral cortex synaptosome and homogenate of the docosahexaenoic acid-fed rats. Arrhenius plot showed a break point in acetylcholinesterase activity at 22 degrees C and 24 degrees C in plasma membranes from docosahexaenoic acid-fed and control rats, respectively. The present experiment indicates that chronic administration of docosahexaenoic acid does not affect synaptic acetylcholinesterase activity and evoke oxidative stress, although it increases the disorder of the global and annular lipids of rat synaptic plasma membranes." @default.
• W2013749215 created "2016-06-24" @default.
• W2013749215 creator A5032896005 @default.
• W2013749215 creator A5056277824 @default.
• W2013749215 creator A5056848475 @default.
• W2013749215 creator A5057614140 @default.
• W2013749215 date "2004-04-01" @default.
• W2013749215 modified "2023-09-26" @default.
• W2013749215 title "Synaptic plasma membrane-bound acetylcholinesterase activity is not affected by docosahexaenoic acid-induced decrease in membrane order" @default.
• W2013749215 cites W107403674 @default.
• W2013749215 cites W1575185153 @default.
• W2013749215 cites W1775749144 @default.
• W2013749215 cites W1865795296 @default.
• W2013749215 cites W1970440189 @default.
• W2013749215 cites W1971048984 @default.
• W2013749215 cites W1974604963 @default.
• W2013749215 cites W1975379307 @default.
• W2013749215 cites W1979364057 @default.
• W2013749215 cites W1983310681 @default.
• W2013749215 cites W1986327799 @default.
• W2013749215 cites W1991079346 @default.
• W2013749215 cites W1992139821 @default.
• W2013749215 cites W1996742027 @default.
• W2013749215 cites W1999453592 @default.
• W2013749215 cites W2005796614 @default.
• W2013749215 cites W2012071630 @default.
• W2013749215 cites W2014055850 @default.
• W2013749215 cites W2014799910 @default.
• W2013749215 cites W2021635942 @default.
• W2013749215 cites W2023902161 @default.
• W2013749215 cites W2024799049 @default.
• W2013749215 cites W2026261400 @default.
• W2013749215 cites W2037094028 @default.
• W2013749215 cites W2040881580 @default.
• W2013749215 cites W2045473630 @default.
• W2013749215 cites W2046122071 @default.
• W2013749215 cites W2048212398 @default.
• W2013749215 cites W2048283355 @default.
• W2013749215 cites W2048410358 @default.
• W2013749215 cites W2055783728 @default.
• W2013749215 cites W2058834304 @default.
• W2013749215 cites W2058845250 @default.
• W2013749215 cites W2059050116 @default.
• W2013749215 cites W2060899416 @default.
• W2013749215 cites W2063328123 @default.
• W2013749215 cites W2066892441 @default.
• W2013749215 cites W2068096880 @default.
• W2013749215 cites W2072387469 @default.
• W2013749215 cites W2081044883 @default.
• W2013749215 cites W2084727223 @default.
• W2013749215 cites W2094509354 @default.
• W2013749215 cites W2094954778 @default.
• W2013749215 cites W2101959021 @default.
• W2013749215 cites W2103279359 @default.
• W2013749215 cites W2116363473 @default.
• W2013749215 cites W2121270809 @default.
• W2013749215 cites W2124068170 @default.
• W2013749215 cites W2129561633 @default.
• W2013749215 cites W2131355633 @default.
• W2013749215 cites W2133451731 @default.
• W2013749215 cites W2160290715 @default.
• W2013749215 cites W2164445091 @default.
• W2013749215 cites W2167230895 @default.
• W2013749215 cites W2168526937 @default.
• W2013749215 cites W2211467290 @default.
• W2013749215 doi "https://doi.org/10.1016/j.lfs.2003.10.028" @default.
• W2013749215 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15051424" @default.
• W2013749215 hasPublicationYear "2004" @default.
• W2013749215 type Work @default.
• W2013749215 sameAs 2013749215 @default.
• W2013749215 citedByCount "23" @default.
• W2013749215 countsByYear W20137492152012 @default.
• W2013749215 countsByYear W20137492152013 @default.
• W2013749215 countsByYear W20137492152014 @default.
• W2013749215 countsByYear W20137492152015 @default.
• W2013749215 countsByYear W20137492152016 @default.
• W2013749215 countsByYear W20137492152017 @default.
• W2013749215 countsByYear W20137492152020 @default.
• W2013749215 crossrefType "journal-article" @default.
• W2013749215 hasAuthorship W2013749215A5032896005 @default.
• W2013749215 hasAuthorship W2013749215A5056277824 @default.
• W2013749215 hasAuthorship W2013749215A5056848475 @default.
• W2013749215 hasAuthorship W2013749215A5057614140 @default.
• W2013749215 hasConcept C126322002 @default.
• W2013749215 hasConcept C134018914 @default.
• W2013749215 hasConcept C181199279 @default.
• W2013749215 hasConcept C185592680 @default.
• W2013749215 hasConcept C19038510 @default.
• W2013749215 hasConcept C2777171753 @default.
• W2013749215 hasConcept C2778078955 @default.
• W2013749215 hasConcept C2778816929 @default.
• W2013749215 hasConcept C2778918659 @default.
• W2013749215 hasConcept C41625074 @default.
• W2013749215 hasConcept C543025807 @default.
• W2013749215 hasConcept C55493867 @default.
• W2013749215 hasConcept C71924100 @default.
• W2013749215 hasConcept C86803240 @default.
• W2013749215 hasConceptScore W2013749215C126322002 @default.

• next