FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2013751227> ?p ?o ?g. }

• W2013751227 endingPage "304" @default.
• W2013751227 startingPage "296" @default.
• W2013751227 abstract "Acute exposure of 3T3-L1 undifferentiated fibroblasts to insulin or 4β-phorbol-12,13-dibutyrate (PDB) produced a moderate but significant stimulation of hexose transport (100% stimulation). In differentiated 3T3-L1 adipocytes, stimulation by insulin increased significantly (to 340%), while that by PDB remained at 130%. Total protein kinase C activity was 3-fold higher in 3T3-L1 fibroblast than adipocyte homogenates. PDB, but not insulin, induced migration of protein kinase C from the cytosol to the membrane, in both fibroblasts and adipocytes. Moreover, the hormone increased by 15% the protein kinase C activity of the cytosol. In 3T3-L1 fibroblasts, both insulin and PDB elicited a rapid (2 min lag) cytoplasmic alkalinization, measured with the fluorescent pH indicator bis-carboxyethyl carboxyfluorescein trapped in the cytoplasm. In 3T3- Ll adipocytes, PDB but not insulin elicited the cytoplasmic alkalinization. The alkalinization was prevented by amiloride or by replacing Na+ with either N-methylglucamine+ or K+. Stimulation of hexose transport by insulin or PDB was not affected by amiloride or Na+ substitution. It is concluded that: 1) Insulin and PDB have different effects on protein kinase C activity and subcellular distribution; 2) the responses of Na+/H+ exchange and hexose transport to insulin and PDB develop independently during differentiation of 3T3-L1 cells; 3) stimulation of Na+/H+ exchange and of hexose transport occur in parallel rather than in series in 3T3-L1 cells. (Endocrinology123: 296–304, 1988)" @default.
• W2013751227 created "2016-06-24" @default.
• W2013751227 creator A5064467789 @default.
• W2013751227 creator A5074380275 @default.
• W2013751227 creator A5091515584 @default.
• W2013751227 date "1988-07-01" @default.
• W2013751227 modified "2023-10-17" @default.
• W2013751227 title "Stimulation of Na⁺/H⁺Exchange by Insulin and Phorbol Ester during Differentiation of 3T3-L1 Cells. Relation to Hexose Uptake*" @default.
• W2013751227 cites W102091409 @default.
• W2013751227 cites W1480299551 @default.
• W2013751227 cites W1483819615 @default.
• W2013751227 cites W1511477344 @default.
• W2013751227 cites W1519754933 @default.
• W2013751227 cites W1524810984 @default.
• W2013751227 cites W1526978170 @default.
• W2013751227 cites W1527546277 @default.
• W2013751227 cites W1575266405 @default.
• W2013751227 cites W1586488610 @default.
• W2013751227 cites W1794291227 @default.
• W2013751227 cites W1964789489 @default.
• W2013751227 cites W1973005880 @default.
• W2013751227 cites W1983326590 @default.
• W2013751227 cites W1985500682 @default.
• W2013751227 cites W1990485429 @default.
• W2013751227 cites W1993515980 @default.
• W2013751227 cites W2001692359 @default.
• W2013751227 cites W2001736800 @default.
• W2013751227 cites W2004523619 @default.
• W2013751227 cites W2018450485 @default.
• W2013751227 cites W2018751358 @default.
• W2013751227 cites W2030413297 @default.
• W2013751227 cites W2039372097 @default.
• W2013751227 cites W2042194183 @default.
• W2013751227 cites W2075648913 @default.
• W2013751227 cites W2088056954 @default.
• W2013751227 cites W2094256878 @default.
• W2013751227 cites W2104481805 @default.
• W2013751227 cites W2106973449 @default.
• W2013751227 cites W2128635872 @default.
• W2013751227 cites W2174970607 @default.
• W2013751227 cites W2196751920 @default.
• W2013751227 cites W2328446029 @default.
• W2013751227 cites W2337521362 @default.
• W2013751227 doi "https://doi.org/10.1210/endo-123-1-296" @default.
• W2013751227 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2838257" @default.
• W2013751227 hasPublicationYear "1988" @default.
• W2013751227 type Work @default.
• W2013751227 sameAs 2013751227 @default.
• W2013751227 citedByCount "32" @default.
• W2013751227 countsByYear W20137512272017 @default.
• W2013751227 countsByYear W20137512272019 @default.
• W2013751227 countsByYear W20137512272021 @default.
• W2013751227 crossrefType "journal-article" @default.
• W2013751227 hasAuthorship W2013751227A5064467789 @default.
• W2013751227 hasAuthorship W2013751227A5074380275 @default.
• W2013751227 hasAuthorship W2013751227A5091515584 @default.
• W2013751227 hasConcept C126322002 @default.
• W2013751227 hasConcept C134018914 @default.
• W2013751227 hasConcept C161573976 @default.
• W2013751227 hasConcept C181199279 @default.
• W2013751227 hasConcept C184235292 @default.
• W2013751227 hasConcept C185592680 @default.
• W2013751227 hasConcept C195794163 @default.
• W2013751227 hasConcept C24998067 @default.
• W2013751227 hasConcept C2776393687 @default.
• W2013751227 hasConcept C2777866211 @default.
• W2013751227 hasConcept C2779306644 @default.
• W2013751227 hasConcept C2780043322 @default.
• W2013751227 hasConcept C55493867 @default.
• W2013751227 hasConcept C65556437 @default.
• W2013751227 hasConcept C71924100 @default.
• W2013751227 hasConcept C86803240 @default.
• W2013751227 hasConcept C97029542 @default.
• W2013751227 hasConceptScore W2013751227C126322002 @default.
• W2013751227 hasConceptScore W2013751227C134018914 @default.
• W2013751227 hasConceptScore W2013751227C161573976 @default.
• W2013751227 hasConceptScore W2013751227C181199279 @default.
• W2013751227 hasConceptScore W2013751227C184235292 @default.
• W2013751227 hasConceptScore W2013751227C185592680 @default.
• W2013751227 hasConceptScore W2013751227C195794163 @default.
• W2013751227 hasConceptScore W2013751227C24998067 @default.
• W2013751227 hasConceptScore W2013751227C2776393687 @default.
• W2013751227 hasConceptScore W2013751227C2777866211 @default.
• W2013751227 hasConceptScore W2013751227C2779306644 @default.
• W2013751227 hasConceptScore W2013751227C2780043322 @default.
• W2013751227 hasConceptScore W2013751227C55493867 @default.
• W2013751227 hasConceptScore W2013751227C65556437 @default.
• W2013751227 hasConceptScore W2013751227C71924100 @default.
• W2013751227 hasConceptScore W2013751227C86803240 @default.
• W2013751227 hasConceptScore W2013751227C97029542 @default.
• W2013751227 hasIssue "1" @default.
• W2013751227 hasLocation W20137512271 @default.
• W2013751227 hasLocation W20137512272 @default.
• W2013751227 hasOpenAccess W2013751227 @default.
• W2013751227 hasPrimaryLocation W20137512271 @default.
• W2013751227 hasRelatedWork W1971859682 @default.
• W2013751227 hasRelatedWork W1974170868 @default.
• W2013751227 hasRelatedWork W1994965139 @default.

• next