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- W2013755149 abstract "For epidemiological and diagnostic applications, detection of virtually all mutations is desired. Herein, blinded analyses of DOVAM-S (Detection Of Virtually All Mutations-SSCP), a robotically enhanced multiplex SSCP method, demonstrate that all of 525 mutations (391 unique) are detected by the method. In addition, the costs of DOVAM-S, gel-based fluorescent sequencing and capillary-based fluorescent sequencing are compared. The relative cost effectiveness of gel-based and capillary-based sequence analysis depends on throughput and whether depreciation and service are considered. DOVAM-S reduces the cost of candidate gene analyses relative to brute force sequencing by about threefold." @default.
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- W2013755149 date "2007-09-01" @default.
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- W2013755149 title "Candidate Gene Analyses by Scanning or Brute Force Fluorescent Sequencing: A Comparison of DOVAM-S with Gel-Based and Capillary-Based Sequencing" @default.
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- W2013755149 doi "https://doi.org/10.1089/gte.2007.9992" @default.
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