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- W2013756061 endingPage "531" @default.
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- W2013756061 abstract "The transition metals zinc, iron and copper are common constituents in a wide range of proteins. Although these metals are all essential for life, when present in excess, they are frequently toxic to cell growth and viability. Therefore, all organisms rely on sophisticated mechanisms to maintain optimal levels of each metal. Genes that encode metal transport or storage proteins are often regulated at the transcriptional level in response to changes in metal status. In this review, we focus on what is known about the transcription factors that mediate these metal-dependent changes. Specifically, we highlight recent advances in our understanding of the mechanisms by which these factors sense metal ions." @default.
- W2013756061 created "2016-06-24" @default.
- W2013756061 creator A5060011957 @default.
- W2013756061 creator A5077040298 @default.
- W2013756061 date "2011-10-01" @default.
- W2013756061 modified "2023-10-13" @default.
- W2013756061 title "Hammering out details: regulating metal levels in eukaryotes" @default.
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- W2013756061 doi "https://doi.org/10.1016/j.tibs.2011.07.002" @default.
- W2013756061 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21840721" @default.
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