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• W2013758414 endingPage "1388" @default.
• W2013758414 startingPage "1379" @default.
• W2013758414 abstract "Cardiovascular disease is the leading cause of death in pediatric patients with chronic kidney disease (CKD), and vascular calcifications start early in the course of CKD. Based on the growing body of evidence that alterations of bone and mineral metabolism and the therapies designed to treat the skeletal consequences of CKD are linked to cardiovascular calcifications, the Kidney Disease, Improving Global Outcomes (KDIGO) working group redefined renal osteodystrophy as a systemic disorder of mineral and bone metabolism due to CKD, and this newly defined disorder is now known as “chronic kidney disease-mineral bone disorder (CKD-MBD)”. Elevated fibroblast growth factor 23 (FGF23), a bone-derived protein, is the first biochemical abnormality to be associated with CKD-MBD, and high FGF23 levels correlate with increased cardiovascular morbidity and mortality, suggesting that bone is central to both initiating and perpetuating the abnormal mineral metabolism and vascular disease in CKD. The current standard therapies for CKD-MBD affect FGF23 levels differently; non-calcium-based binders with or without concurrent use of dietary phosphate restriction reduce FGF23 levels, while calcium-based binders seem to either increase or have no effect on FGF23 levels. Active vitamin D sterols increase FGF23 levels, whereas therapy with calcimimetics decreases FGF23 levels. Thus, the appropriate therapy that will minimize the rise in FGF23 and prevent cardiovascular morbidity remains to be defined." @default.
• W2013758414 created "2016-06-24" @default.
• W2013758414 creator A5030979898 @default.
• W2013758414 creator A5061322949 @default.
• W2013758414 creator A5084811951 @default.
• W2013758414 date "2014-08-29" @default.
• W2013758414 modified "2023-09-26" @default.
• W2013758414 title "The role of bone in CKD-mediated mineral and vascular disease" @default.
• W2013758414 cites W1803609188 @default.
• W2013758414 cites W1967330581 @default.
• W2013758414 cites W1968144869 @default.
• W2013758414 cites W1969840644 @default.
• W2013758414 cites W1976544899 @default.
• W2013758414 cites W1979425916 @default.
• W2013758414 cites W1981228902 @default.
• W2013758414 cites W1982290615 @default.
• W2013758414 cites W1985963651 @default.
• W2013758414 cites W1988897099 @default.
• W2013758414 cites W1996731541 @default.
• W2013758414 cites W1996737012 @default.
• W2013758414 cites W2009949027 @default.
• W2013758414 cites W2009995285 @default.
• W2013758414 cites W2013009411 @default.
• W2013758414 cites W2015668150 @default.
• W2013758414 cites W2017591034 @default.
• W2013758414 cites W2021514219 @default.
• W2013758414 cites W2021852822 @default.
• W2013758414 cites W2025106435 @default.
• W2013758414 cites W2025589168 @default.
• W2013758414 cites W2030174339 @default.
• W2013758414 cites W2030777261 @default.
• W2013758414 cites W2031567798 @default.
• W2013758414 cites W2035221187 @default.
• W2013758414 cites W2041242683 @default.
• W2013758414 cites W2042256973 @default.
• W2013758414 cites W2048729813 @default.
• W2013758414 cites W2053152115 @default.
• W2013758414 cites W2054323843 @default.
• W2013758414 cites W2055627538 @default.
• W2013758414 cites W2057944952 @default.
• W2013758414 cites W2058579856 @default.
• W2013758414 cites W2067547765 @default.
• W2013758414 cites W2069290111 @default.
• W2013758414 cites W2078382957 @default.
• W2013758414 cites W2084180690 @default.
• W2013758414 cites W2086014383 @default.
• W2013758414 cites W2087387262 @default.
• W2013758414 cites W2093535053 @default.
• W2013758414 cites W2095804181 @default.
• W2013758414 cites W2096024580 @default.
• W2013758414 cites W2097969657 @default.
• W2013758414 cites W2098056273 @default.
• W2013758414 cites W2101912981 @default.
• W2013758414 cites W2102020399 @default.
• W2013758414 cites W2102734552 @default.
• W2013758414 cites W2104612852 @default.
• W2013758414 cites W2105288874 @default.
• W2013758414 cites W2105417592 @default.
• W2013758414 cites W2105898297 @default.
• W2013758414 cites W2107420262 @default.
• W2013758414 cites W2109064733 @default.
• W2013758414 cites W2109177164 @default.
• W2013758414 cites W2111094568 @default.
• W2013758414 cites W2111614075 @default.
• W2013758414 cites W2113340104 @default.
• W2013758414 cites W2113356410 @default.
• W2013758414 cites W2114360920 @default.
• W2013758414 cites W2118752987 @default.
• W2013758414 cites W2120129493 @default.
• W2013758414 cites W2120166750 @default.
• W2013758414 cites W2121270324 @default.
• W2013758414 cites W2121435915 @default.
• W2013758414 cites W2122037712 @default.
• W2013758414 cites W2124526413 @default.
• W2013758414 cites W2124591820 @default.
• W2013758414 cites W2126411348 @default.
• W2013758414 cites W2129015099 @default.
• W2013758414 cites W2129352623 @default.
• W2013758414 cites W2133134475 @default.
• W2013758414 cites W2137591192 @default.
• W2013758414 cites W2137743950 @default.
• W2013758414 cites W2138484848 @default.
• W2013758414 cites W2138484858 @default.
• W2013758414 cites W2140610989 @default.
• W2013758414 cites W2145582432 @default.
• W2013758414 cites W2145632027 @default.
• W2013758414 cites W2150384701 @default.
• W2013758414 cites W2152171089 @default.
• W2013758414 cites W2153481494 @default.
• W2013758414 cites W2154497747 @default.
• W2013758414 cites W2157448600 @default.
• W2013758414 cites W2159323221 @default.
• W2013758414 cites W2163181937 @default.
• W2013758414 cites W2164510761 @default.
• W2013758414 cites W2166512947 @default.
• W2013758414 cites W2167092665 @default.
• W2013758414 cites W2168855220 @default.
• W2013758414 cites W2170349110 @default.

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