FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2013774562> ?p ?o ?g. }

• W2013774562 endingPage "468" @default.
• W2013774562 startingPage "463" @default.
• W2013774562 abstract "Non-steroidal anti-inflammatory drugs (NSAIDs) are strongly associated with gastroduodenal ulcers, and the management of patients with NSAID-associated ulcers represents a common clinical dilemma.To assess NSAID-associated ulcer healing during treatment with either standard (20 mg) or high dosage (40 mg) omeprazole.One hundred and sixty-nine patients chronically ingesting diclofenac, ketoprofen, indomethacin or naproxen for osteoarthritis or rheumatoid arthritis, who had abdominal pain and an endoscopically proven gastroduodenal ulcer, were evaluated in a randomized, double-blind, dose regimen trial with omeprazole 20 mg o.m. (n = 81) or omeprazole 40 mg o.m. (n = 88). Ulcer healing was assessed endoscopically at 4 and 8 weeks in the case of unhealed ulcers. Patients continued their usual daily dose of anti-inflammatory medication throughout the study period.One hundred and fifty-six patients completed the study (77 patients taking 20 mg omeprazole and 79 patients taking 40 mg omeprazole); 12 patients were lost during follow-up and one patient reported an adverse event. Cumulative ulcer intention-to-treat healing rates at 8 weeks were 88% (95% confidence interval (CI) = 79-95%) for the 20 mg omeprazole group and 96.2% (95% CI = 89-99%) for the 40 mg group, and 97.1% (95% CI = 90-100%) for the 20 mg omeprazole group and 98.6% (95% CI = 93-100%) for the 40 mg group by per protocol analysis. There were no statistically significant differences between the two groups. Symptom relief did not differ significantly between the two treatment groups.Both standard and high doses of omeprazole are equally safe and effective regimens for the treatment of NSAID-induced gastroduodenal ulcers when anti-inflammatory treatment is not discontinued." @default.
• W2013774562 created "2016-06-24" @default.
• W2013774562 creator A5016121240 @default.
• W2013774562 creator A5035332783 @default.
• W2013774562 creator A5035396388 @default.
• W2013774562 creator A5039932053 @default.
• W2013774562 creator A5044933779 @default.
• W2013774562 creator A5057774444 @default.
• W2013774562 date "1998-05-01" @default.
• W2013774562 modified "2023-09-27" @default.
• W2013774562 title "Omeprazole 20 or 40 mg daily for healing gastroduodenal ulcers in patients receiving non-steroidal anti-inflammatory drugs" @default.
• W2013774562 cites W1866834673 @default.
• W2013774562 cites W1964056979 @default.
• W2013774562 cites W1975266699 @default.
• W2013774562 cites W1996284297 @default.
• W2013774562 cites W1998161037 @default.
• W2013774562 cites W1998791587 @default.
• W2013774562 cites W2001350224 @default.
• W2013774562 cites W2005002369 @default.
• W2013774562 cites W2014348672 @default.
• W2013774562 cites W2031760606 @default.
• W2013774562 cites W2036268181 @default.
• W2013774562 cites W2047446796 @default.
• W2013774562 cites W2048567767 @default.
• W2013774562 cites W2051691071 @default.
• W2013774562 cites W2054154014 @default.
• W2013774562 cites W2063418838 @default.
• W2013774562 cites W2084678619 @default.
• W2013774562 cites W2093711760 @default.
• W2013774562 cites W2094502777 @default.
• W2013774562 cites W2128557023 @default.
• W2013774562 cites W2165368238 @default.
• W2013774562 cites W2167378024 @default.
• W2013774562 cites W2330367835 @default.
• W2013774562 cites W2339197236 @default.
• W2013774562 doi "https://doi.org/10.1046/j.1365-2036.1998.00331.x" @default.
• W2013774562 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9663727" @default.
• W2013774562 hasPublicationYear "1998" @default.
• W2013774562 type Work @default.
• W2013774562 sameAs 2013774562 @default.
• W2013774562 citedByCount "11" @default.
• W2013774562 countsByYear W20137745622015 @default.
• W2013774562 countsByYear W20137745622016 @default.
• W2013774562 countsByYear W20137745622022 @default.
• W2013774562 countsByYear W20137745622023 @default.
• W2013774562 crossrefType "journal-article" @default.
• W2013774562 hasAuthorship W2013774562A5016121240 @default.
• W2013774562 hasAuthorship W2013774562A5035332783 @default.
• W2013774562 hasAuthorship W2013774562A5035396388 @default.
• W2013774562 hasAuthorship W2013774562A5039932053 @default.
• W2013774562 hasAuthorship W2013774562A5044933779 @default.
• W2013774562 hasAuthorship W2013774562A5057774444 @default.
• W2013774562 hasBestOaLocation W20137745621 @default.
• W2013774562 hasConcept C126322002 @default.
• W2013774562 hasConcept C141071460 @default.
• W2013774562 hasConcept C142724271 @default.
• W2013774562 hasConcept C168563851 @default.
• W2013774562 hasConcept C197934379 @default.
• W2013774562 hasConcept C204787440 @default.
• W2013774562 hasConcept C2776164576 @default.
• W2013774562 hasConcept C2777077863 @default.
• W2013774562 hasConcept C2777498785 @default.
• W2013774562 hasConcept C2777575956 @default.
• W2013774562 hasConcept C2779826273 @default.
• W2013774562 hasConcept C2781413609 @default.
• W2013774562 hasConcept C42219234 @default.
• W2013774562 hasConcept C71924100 @default.
• W2013774562 hasConcept C90924648 @default.
• W2013774562 hasConceptScore W2013774562C126322002 @default.
• W2013774562 hasConceptScore W2013774562C141071460 @default.
• W2013774562 hasConceptScore W2013774562C142724271 @default.
• W2013774562 hasConceptScore W2013774562C168563851 @default.
• W2013774562 hasConceptScore W2013774562C197934379 @default.
• W2013774562 hasConceptScore W2013774562C204787440 @default.
• W2013774562 hasConceptScore W2013774562C2776164576 @default.
• W2013774562 hasConceptScore W2013774562C2777077863 @default.
• W2013774562 hasConceptScore W2013774562C2777498785 @default.
• W2013774562 hasConceptScore W2013774562C2777575956 @default.
• W2013774562 hasConceptScore W2013774562C2779826273 @default.
• W2013774562 hasConceptScore W2013774562C2781413609 @default.
• W2013774562 hasConceptScore W2013774562C42219234 @default.
• W2013774562 hasConceptScore W2013774562C71924100 @default.
• W2013774562 hasConceptScore W2013774562C90924648 @default.
• W2013774562 hasIssue "5" @default.
• W2013774562 hasLocation W20137745621 @default.
• W2013774562 hasLocation W20137745622 @default.
• W2013774562 hasOpenAccess W2013774562 @default.
• W2013774562 hasPrimaryLocation W20137745621 @default.
• W2013774562 hasRelatedWork W2031158406 @default.
• W2013774562 hasRelatedWork W2069514211 @default.
• W2013774562 hasRelatedWork W2094490928 @default.
• W2013774562 hasRelatedWork W2133848536 @default.
• W2013774562 hasRelatedWork W2171452673 @default.
• W2013774562 hasRelatedWork W2292433088 @default.
• W2013774562 hasRelatedWork W2362235535 @default.
• W2013774562 hasRelatedWork W2773421678 @default.
• W2013774562 hasRelatedWork W2797722083 @default.
• W2013774562 hasRelatedWork W2913496100 @default.

• next