Matches in SemOpenAlex for { <https://semopenalex.org/work/W2013784180> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2013784180 endingPage "447" @default.
- W2013784180 startingPage "433" @default.
- W2013784180 abstract "Karyotypes and X chromosome inactivation were studied in embryos obtained from female mice carrying T(X ;4)37H translocation on day 6 to 8 of gestation by a BrdU-acridine orange method. A total of 18 different karyotypes were found in 477 embryos examined: 90.0% embryos were products expected from 2:2 alternate or adjacent 1 disjunction. 3:1 and adjacent 2 disjunctions accounted for approximately 8.0% and 0.7% conceptuses, respectively. In the embryo proper of balanced T37H/ + conceptuses, inactivation was random with respect to the normal X and the larger translocation X (4X) chromosome. In all the cells with the 4X inactive, the late replication apparently did not spread to the attached autosomal portion, although black/brown coat variegation implies spreading of inactivation into the autosomal region. The X chromosome segment deprived of the inactivation center remained active in all the cells examined and it exerted deleterious effects on embryonic or fetal development. Observation in embryos having two maternally derived X chromosomes showed that they were indeed resistant to inactivation in early extraembryonic cell lineages, and two copies of active X chromosomes in the trophectoderm fatally affected embryonic development due to inability to form the extraembryonic ectoderm and ectoplacental cone from the polar trophectoderm. In unbalanced X aneuploids the X chromosomes with the deletion were preferentially inactivated due to strong selection against nullisomy X." @default.
- W2013784180 created "2016-06-24" @default.
- W2013784180 creator A5047791990 @default.
- W2013784180 creator A5069773719 @default.
- W2013784180 date "1991-01-01" @default.
- W2013784180 modified "2023-09-26" @default.
- W2013784180 title "Karyotypes and X chromosome inactivation in segregants of a murine X-autosome translocation, T(X;4)37H." @default.
- W2013784180 cites W1556630663 @default.
- W2013784180 cites W1841178034 @default.
- W2013784180 cites W1868997293 @default.
- W2013784180 cites W1882649803 @default.
- W2013784180 cites W1963885483 @default.
- W2013784180 cites W1973445288 @default.
- W2013784180 cites W1982392278 @default.
- W2013784180 cites W1986156899 @default.
- W2013784180 cites W1994400527 @default.
- W2013784180 cites W2012412628 @default.
- W2013784180 cites W2013006611 @default.
- W2013784180 cites W2013815895 @default.
- W2013784180 cites W2021122622 @default.
- W2013784180 cites W2029146706 @default.
- W2013784180 cites W2031531472 @default.
- W2013784180 cites W2033760492 @default.
- W2013784180 cites W2068379308 @default.
- W2013784180 cites W2079597045 @default.
- W2013784180 cites W2088880228 @default.
- W2013784180 cites W2093622002 @default.
- W2013784180 cites W2093645458 @default.
- W2013784180 cites W2112466032 @default.
- W2013784180 cites W2127186607 @default.
- W2013784180 cites W2135678432 @default.
- W2013784180 cites W321073741 @default.
- W2013784180 doi "https://doi.org/10.1266/jjg.66.433" @default.
- W2013784180 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1954036" @default.
- W2013784180 hasPublicationYear "1991" @default.
- W2013784180 type Work @default.
- W2013784180 sameAs 2013784180 @default.
- W2013784180 citedByCount "2" @default.
- W2013784180 crossrefType "journal-article" @default.
- W2013784180 hasAuthorship W2013784180A5047791990 @default.
- W2013784180 hasAuthorship W2013784180A5069773719 @default.
- W2013784180 hasBestOaLocation W20137841801 @default.
- W2013784180 hasConcept C104317684 @default.
- W2013784180 hasConcept C134925867 @default.
- W2013784180 hasConcept C138626823 @default.
- W2013784180 hasConcept C153911025 @default.
- W2013784180 hasConcept C159399396 @default.
- W2013784180 hasConcept C196843134 @default.
- W2013784180 hasConcept C2778177303 @default.
- W2013784180 hasConcept C30278631 @default.
- W2013784180 hasConcept C30481170 @default.
- W2013784180 hasConcept C35158069 @default.
- W2013784180 hasConcept C4323932 @default.
- W2013784180 hasConcept C53226629 @default.
- W2013784180 hasConcept C54355233 @default.
- W2013784180 hasConcept C86803240 @default.
- W2013784180 hasConcept C87073359 @default.
- W2013784180 hasConceptScore W2013784180C104317684 @default.
- W2013784180 hasConceptScore W2013784180C134925867 @default.
- W2013784180 hasConceptScore W2013784180C138626823 @default.
- W2013784180 hasConceptScore W2013784180C153911025 @default.
- W2013784180 hasConceptScore W2013784180C159399396 @default.
- W2013784180 hasConceptScore W2013784180C196843134 @default.
- W2013784180 hasConceptScore W2013784180C2778177303 @default.
- W2013784180 hasConceptScore W2013784180C30278631 @default.
- W2013784180 hasConceptScore W2013784180C30481170 @default.
- W2013784180 hasConceptScore W2013784180C35158069 @default.
- W2013784180 hasConceptScore W2013784180C4323932 @default.
- W2013784180 hasConceptScore W2013784180C53226629 @default.
- W2013784180 hasConceptScore W2013784180C54355233 @default.
- W2013784180 hasConceptScore W2013784180C86803240 @default.
- W2013784180 hasConceptScore W2013784180C87073359 @default.
- W2013784180 hasIssue "4" @default.
- W2013784180 hasLocation W20137841801 @default.
- W2013784180 hasLocation W20137841802 @default.
- W2013784180 hasOpenAccess W2013784180 @default.
- W2013784180 hasPrimaryLocation W20137841801 @default.
- W2013784180 hasRelatedWork W1501479844 @default.
- W2013784180 hasRelatedWork W1685573588 @default.
- W2013784180 hasRelatedWork W1985835648 @default.
- W2013784180 hasRelatedWork W2013784180 @default.
- W2013784180 hasRelatedWork W2015597212 @default.
- W2013784180 hasRelatedWork W2034820368 @default.
- W2013784180 hasRelatedWork W2086609201 @default.
- W2013784180 hasRelatedWork W2122320241 @default.
- W2013784180 hasRelatedWork W2127186607 @default.
- W2013784180 hasRelatedWork W2794033488 @default.
- W2013784180 hasVolume "66" @default.
- W2013784180 isParatext "false" @default.
- W2013784180 isRetracted "false" @default.
- W2013784180 magId "2013784180" @default.
- W2013784180 workType "article" @default.