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- W2013799252 abstract "ABSTRACT Recombinant vesicular stomatitis virus (VSV) is a promising therapeutic vaccine platform. Using a transgenic mouse model of chronic hepatitis B virus (HBV) infection, we evaluated the therapeutic potential of a VSV vector expressing the HBV middle surface envelope glycoprotein (MS). VSV-MS immunization generated HBV-specific CD8 T cell and antibody responses in transgenic mice that express low HBV antigen levels. These findings support the further development of VSV as a therapeutic vaccine vector for chronic HBV." @default.
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- W2013799252 date "2013-03-01" @default.
- W2013799252 modified "2023-09-28" @default.
- W2013799252 title "A Vesicular Stomatitis Virus-Based Therapeutic Vaccine Generates a Functional CD8 T Cell Response to Hepatitis B Virus in Transgenic Mice" @default.
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- W2013799252 doi "https://doi.org/10.1128/jvi.02111-12" @default.
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