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- W2013804946 abstract "This review summarizes results of our recent solid-state NMR investigations on polyunsaturated 18:0-22:6n3-PC/PE/PS and 18:0-22:5n6-PC bilayers. Data on structure and dynamics of the polyunsaturated docosahexaenoyl (DHAn3, 22:6n3) and docosapentaenoyl chains (DPAn6, 22:5n6), investigated at physiological conditions, are reported. Lipid–protein interaction was studied on reconstituted bilayers containing the G-protein coupled membrane receptor (GPCR) rhodopsin as well as on rod outer segment (ROS) disk membranes prepared from bovine retinas. Results reveal surprisingly rapid conformational transitions of polyunsaturated chains and existence of weakly specific interactions of DHAn3 with spatially distinct sites on rhodopsin." @default.
- W2013804946 created "2016-06-24" @default.
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- W2013804946 date "2008-05-01" @default.
- W2013804946 modified "2023-09-25" @default.
- W2013804946 title "Structure and dynamics of polyunsaturated hydrocarbon chains in lipid bilayers—significance for GPCR function" @default.
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- W2013804946 doi "https://doi.org/10.1016/j.chemphyslip.2008.02.016" @default.
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