Matches in SemOpenAlex for { <https://semopenalex.org/work/W2013806540> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2013806540 endingPage "845" @default.
- W2013806540 startingPage "833" @default.
- W2013806540 abstract "1. Mianserin is a tetracyclic antidepressant with relatively few anticholinergic and cardiovascular side-effects. Its clinical efficacy is comparable to that of tricyclic antidepressants. It is widely used in Europe, especially in elderly outpatients. 2. In the present studies, the authors have evaluated the efficacy of mianserin as well as the effects of ageing and concomitant psychotropic drugs on serum mianserin concentrations in 169 depressive psychiatric inpatients. 3. In the patients the mean serum mianserin concentrations or their interindividual variations did not differ between the old, middle-aged, and young age groups. Furthermore, elderly women and men did not differ from each other for their dose-related drug concentrations. Neither were any differences found in serum mianserin concentrations between the older (> or = 75 years) and younger elderly (65-74). As is the case with TCAs, the co-administration of neuroleptics increased serum mianserin concentrations in the elderly. When comparing the therapeutic response and serum mianserin concentrations the authors found that the patients with good clinical improvement had higher mean serum mianserin concentrations than those without efficacy. 4. There seem to be no clinically important changes in the pharmacokinetics of mianserin with advancing age. The present results do not support the claim that the therapeutic profile of this drug is altered with advancing age. Mianserin can be regarded as an antidepressant with relatively few side-effects in the elderly." @default.
- W2013806540 created "2016-06-24" @default.
- W2013806540 creator A5013165494 @default.
- W2013806540 creator A5039822970 @default.
- W2013806540 creator A5041186125 @default.
- W2013806540 date "1994-09-01" @default.
- W2013806540 modified "2023-10-01" @default.
- W2013806540 title "Serum mianserin and ageing" @default.
- W2013806540 cites W1965551044 @default.
- W2013806540 cites W1966943560 @default.
- W2013806540 cites W1982177121 @default.
- W2013806540 cites W2002642996 @default.
- W2013806540 cites W2021108150 @default.
- W2013806540 cites W2031017946 @default.
- W2013806540 cites W2050605779 @default.
- W2013806540 cites W2053620670 @default.
- W2013806540 cites W2063085120 @default.
- W2013806540 cites W2071923825 @default.
- W2013806540 cites W2074812439 @default.
- W2013806540 cites W2079220380 @default.
- W2013806540 cites W2085365507 @default.
- W2013806540 cites W2087531241 @default.
- W2013806540 cites W2089111061 @default.
- W2013806540 cites W2094258862 @default.
- W2013806540 cites W2094725292 @default.
- W2013806540 cites W2111394637 @default.
- W2013806540 cites W2121439050 @default.
- W2013806540 cites W2136082539 @default.
- W2013806540 cites W2137792927 @default.
- W2013806540 cites W2402949234 @default.
- W2013806540 cites W2464952221 @default.
- W2013806540 cites W4250766864 @default.
- W2013806540 doi "https://doi.org/10.1016/0278-5846(94)90100-7" @default.
- W2013806540 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7972855" @default.
- W2013806540 hasPublicationYear "1994" @default.
- W2013806540 type Work @default.
- W2013806540 sameAs 2013806540 @default.
- W2013806540 citedByCount "167" @default.
- W2013806540 countsByYear W20138065402017 @default.
- W2013806540 countsByYear W20138065402020 @default.
- W2013806540 crossrefType "journal-article" @default.
- W2013806540 hasAuthorship W2013806540A5013165494 @default.
- W2013806540 hasAuthorship W2013806540A5039822970 @default.
- W2013806540 hasAuthorship W2013806540A5041186125 @default.
- W2013806540 hasConcept C112705442 @default.
- W2013806540 hasConcept C126322002 @default.
- W2013806540 hasConcept C2778689640 @default.
- W2013806540 hasConcept C2779177272 @default.
- W2013806540 hasConcept C2780035454 @default.
- W2013806540 hasConcept C2780831388 @default.
- W2013806540 hasConcept C2781081902 @default.
- W2013806540 hasConcept C2781161787 @default.
- W2013806540 hasConcept C500499127 @default.
- W2013806540 hasConcept C71924100 @default.
- W2013806540 hasConcept C98274493 @default.
- W2013806540 hasConceptScore W2013806540C112705442 @default.
- W2013806540 hasConceptScore W2013806540C126322002 @default.
- W2013806540 hasConceptScore W2013806540C2778689640 @default.
- W2013806540 hasConceptScore W2013806540C2779177272 @default.
- W2013806540 hasConceptScore W2013806540C2780035454 @default.
- W2013806540 hasConceptScore W2013806540C2780831388 @default.
- W2013806540 hasConceptScore W2013806540C2781081902 @default.
- W2013806540 hasConceptScore W2013806540C2781161787 @default.
- W2013806540 hasConceptScore W2013806540C500499127 @default.
- W2013806540 hasConceptScore W2013806540C71924100 @default.
- W2013806540 hasConceptScore W2013806540C98274493 @default.
- W2013806540 hasIssue "5" @default.
- W2013806540 hasLocation W20138065401 @default.
- W2013806540 hasLocation W20138065402 @default.
- W2013806540 hasOpenAccess W2013806540 @default.
- W2013806540 hasPrimaryLocation W20138065401 @default.
- W2013806540 hasRelatedWork W138236083 @default.
- W2013806540 hasRelatedWork W1491716273 @default.
- W2013806540 hasRelatedWork W185885374 @default.
- W2013806540 hasRelatedWork W1993534000 @default.
- W2013806540 hasRelatedWork W2013806540 @default.
- W2013806540 hasRelatedWork W2093012484 @default.
- W2013806540 hasRelatedWork W2124755695 @default.
- W2013806540 hasRelatedWork W2168239392 @default.
- W2013806540 hasRelatedWork W4289988755 @default.
- W2013806540 hasRelatedWork W885742342 @default.
- W2013806540 hasVolume "18" @default.
- W2013806540 isParatext "false" @default.
- W2013806540 isRetracted "false" @default.
- W2013806540 magId "2013806540" @default.
- W2013806540 workType "article" @default.