FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2013808900> ?p ?o ?g. }

• W2013808900 abstract "It has been questioned whether prenatal exposure to progesterone, like exposure to diethylstilbestrol (DES), results in teratogenic abnormalities of the upper and lower genital tract in human females. Through the use of a recently described model in which human fetal reproductive tracts can be transplanted and grown in vivo for extended periods in athymic nude mice, genital tracts from human female fetuses, ages 7 to 18 weeks postovulation, were grafted into castrated murine hosts and grown for 4 to 10 weeks in the presence or absence of continuous exposure to progesterone. Substantial growth was observed. For all specimens, the morphogenetic process proceeded normally, resulting in the harmonious organization of a complete, well differentiated genital tract composed of fallopian tubes, uterine corpus, and cervix and vagina. The fallopian tubes were highly convoluted and disclosed fimbria. The uterine corpus was lined by a simple columnar epithelium; two layers of stroma in the wall were distinctly separated from each other. In the older specimens, the outer layer of stroma had assumed microscopic properties diagnostic of smooth muscle (myometrium). In the majority of specimens the region of the cervix/vagina disclosed the development of a fornix-like evagination at which point or slightly cranially there was a gradual but defined transition from columnar epithelium to squamous epithelium. The inner layer of endometrial stroma tapered and disappeared at or close to the squamocolumnar junction. The vaginal stroma was a single homogeneous layer and was continuous with the myometrium of the uterine corpus. In the context of this model system, prenatal exposure of the developing human female genital tract of progesterone was not associated with any obvious teratogenic effects." @default.
• W2013808900 created "2016-06-24" @default.
• W2013808900 creator A5013321556 @default.
• W2013808900 creator A5033425459 @default.
• W2013808900 creator A5039133602 @default.
• W2013808900 creator A5065328069 @default.
• W2013808900 creator A5079563340 @default.
• W2013808900 creator A5091506935 @default.
• W2013808900 date "1988-07-01" @default.
• W2013808900 modified "2023-09-23" @default.
• W2013808900 title "Absence of teratogenic effects of progesterone on the developing genital tract of the human female fetus" @default.
• W2013808900 cites W1491974427 @default.
• W2013808900 cites W1518093880 @default.
• W2013808900 cites W1523180751 @default.
• W2013808900 cites W1586115703 @default.
• W2013808900 cites W1881780935 @default.
• W2013808900 cites W1932880267 @default.
• W2013808900 cites W1980524281 @default.
• W2013808900 cites W2001148799 @default.
• W2013808900 cites W2005632323 @default.
• W2013808900 cites W2011920442 @default.
• W2013808900 cites W2012216395 @default.
• W2013808900 cites W2015288212 @default.
• W2013808900 cites W2021990133 @default.
• W2013808900 cites W2039604239 @default.
• W2013808900 cites W2048914959 @default.
• W2013808900 cites W2070309939 @default.
• W2013808900 cites W2071071469 @default.
• W2013808900 cites W2086967915 @default.
• W2013808900 cites W2144114758 @default.
• W2013808900 cites W2337062834 @default.
• W2013808900 cites W2346153620 @default.
• W2013808900 cites W2395980037 @default.
• W2013808900 cites W2902914441 @default.
• W2013808900 cites W4211203108 @default.
• W2013808900 cites W69789317 @default.
• W2013808900 doi "https://doi.org/10.1016/s0046-8177(88)80260-0" @default.
• W2013808900 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3402971" @default.
• W2013808900 hasPublicationYear "1988" @default.
• W2013808900 type Work @default.
• W2013808900 sameAs 2013808900 @default.
• W2013808900 citedByCount "11" @default.
• W2013808900 countsByYear W20138089002016 @default.
• W2013808900 countsByYear W20138089002017 @default.
• W2013808900 countsByYear W20138089002018 @default.
• W2013808900 crossrefType "journal-article" @default.
• W2013808900 hasAuthorship W2013808900A5013321556 @default.
• W2013808900 hasAuthorship W2013808900A5033425459 @default.
• W2013808900 hasAuthorship W2013808900A5039133602 @default.
• W2013808900 hasAuthorship W2013808900A5065328069 @default.
• W2013808900 hasAuthorship W2013808900A5079563340 @default.
• W2013808900 hasAuthorship W2013808900A5091506935 @default.
• W2013808900 hasConcept C105702510 @default.
• W2013808900 hasConcept C121608353 @default.
• W2013808900 hasConcept C134018914 @default.
• W2013808900 hasConcept C203014093 @default.
• W2013808900 hasConcept C204232928 @default.
• W2013808900 hasConcept C2775883341 @default.
• W2013808900 hasConcept C2777479560 @default.
• W2013808900 hasConcept C2777740455 @default.
• W2013808900 hasConcept C2777744392 @default.
• W2013808900 hasConcept C2778164554 @default.
• W2013808900 hasConcept C2779066055 @default.
• W2013808900 hasConcept C2910118542 @default.
• W2013808900 hasConcept C52124034 @default.
• W2013808900 hasConcept C529295009 @default.
• W2013808900 hasConcept C54355233 @default.
• W2013808900 hasConcept C86803240 @default.
• W2013808900 hasConceptScore W2013808900C105702510 @default.
• W2013808900 hasConceptScore W2013808900C121608353 @default.
• W2013808900 hasConceptScore W2013808900C134018914 @default.
• W2013808900 hasConceptScore W2013808900C203014093 @default.
• W2013808900 hasConceptScore W2013808900C204232928 @default.
• W2013808900 hasConceptScore W2013808900C2775883341 @default.
• W2013808900 hasConceptScore W2013808900C2777479560 @default.
• W2013808900 hasConceptScore W2013808900C2777740455 @default.
• W2013808900 hasConceptScore W2013808900C2777744392 @default.
• W2013808900 hasConceptScore W2013808900C2778164554 @default.
• W2013808900 hasConceptScore W2013808900C2779066055 @default.
• W2013808900 hasConceptScore W2013808900C2910118542 @default.
• W2013808900 hasConceptScore W2013808900C52124034 @default.
• W2013808900 hasConceptScore W2013808900C529295009 @default.
• W2013808900 hasConceptScore W2013808900C54355233 @default.
• W2013808900 hasConceptScore W2013808900C86803240 @default.
• W2013808900 hasLocation W20138089001 @default.
• W2013808900 hasLocation W20138089002 @default.
• W2013808900 hasOpenAccess W2013808900 @default.
• W2013808900 hasPrimaryLocation W20138089001 @default.
• W2013808900 hasRelatedWork W108119537 @default.
• W2013808900 hasRelatedWork W1500825527 @default.
• W2013808900 hasRelatedWork W1542854296 @default.
• W2013808900 hasRelatedWork W1976008820 @default.
• W2013808900 hasRelatedWork W1998604434 @default.
• W2013808900 hasRelatedWork W2013808900 @default.
• W2013808900 hasRelatedWork W2050946106 @default.
• W2013808900 hasRelatedWork W2164127681 @default.
• W2013808900 hasRelatedWork W2335767556 @default.
• W2013808900 hasRelatedWork W2411331146 @default.
• W2013808900 isParatext "false" @default.
• W2013808900 isRetracted "false" @default.

• next