Matches in SemOpenAlex for { <https://semopenalex.org/work/W2013819703> ?p ?o ?g. }
- W2013819703 endingPage "3786" @default.
- W2013819703 startingPage "3777" @default.
- W2013819703 abstract "ABSTRACT Members of the phylum “ Synergistetes ” have frequently been detected in the human oral cavity at sites of dental disease, but they have rarely been detected in studies of oral health. Only two oral “ Synergistetes ” taxa are cultivable. The aims of this study were to investigate the diversity of “ Synergistetes ” in the oral cavity, to establish whether “ Synergistetes ” taxa are more strongly associated with periodontitis than with oral health, and to visualize unculturable “ Synergistetes ” in situ. Sixty samples (saliva, dental plaque, and mucosal swabs) were collected from five subjects with periodontitis and five periodontally healthy controls. Using phylum-specific 16S rRNA gene primers, “ Synergistetes ” were identified by PCR, cloning, and sequencing of 48 clones per PCR-positive sample. Subgingival plaque samples were labeled with probes targeting rRNA of unculturable oral “ Synergistetes ” using fluorescent in situ hybridization (FISH). Analysis of 1,664 clones revealed 12 “ Synergistetes ” operational taxonomic units (OTUs) at the 99% sequence identity level, 5 of which were novel. “ Synergistetes ” OTU 4.2 was found in significantly more subjects with periodontitis than controls ( P = 0.048) and was more abundant in subgingival plaque at diseased sites than at healthy sites in subjects with periodontitis ( P = 0.019) or controls ( P = 0.019). FISH analysis revealed that unculturable oral “ Synergistetes ” cells were large curved bacilli. The human oral cavity harbors a diverse population of “ Synergistetes. ” “ Synergistetes ” OTU 4.2 is associated with periodontitis and may have a pathogenic role." @default.
- W2013819703 created "2016-06-24" @default.
- W2013819703 creator A5040100787 @default.
- W2013819703 creator A5043169515 @default.
- W2013819703 creator A5056199248 @default.
- W2013819703 date "2009-06-01" @default.
- W2013819703 modified "2023-10-01" @default.
- W2013819703 title "Diversity and Morphology of Members of the Phylum “ <i>Synergistetes</i> ” in Periodontal Health and Disease" @default.
- W2013819703 cites W1484547139 @default.
- W2013819703 cites W1603861003 @default.
- W2013819703 cites W1701869895 @default.
- W2013819703 cites W1900470258 @default.
- W2013819703 cites W1969062705 @default.
- W2013819703 cites W1974427319 @default.
- W2013819703 cites W1979432701 @default.
- W2013819703 cites W1980873478 @default.
- W2013819703 cites W1981592019 @default.
- W2013819703 cites W1987016801 @default.
- W2013819703 cites W2009507089 @default.
- W2013819703 cites W2010290066 @default.
- W2013819703 cites W2019094601 @default.
- W2013819703 cites W2022300029 @default.
- W2013819703 cites W2034336135 @default.
- W2013819703 cites W2043675432 @default.
- W2013819703 cites W2052639964 @default.
- W2013819703 cites W2095566926 @default.
- W2013819703 cites W2095992358 @default.
- W2013819703 cites W2096917307 @default.
- W2013819703 cites W2097382368 @default.
- W2013819703 cites W2106020100 @default.
- W2013819703 cites W2107228383 @default.
- W2013819703 cites W2111775329 @default.
- W2013819703 cites W2131952844 @default.
- W2013819703 cites W2133664523 @default.
- W2013819703 cites W2142250645 @default.
- W2013819703 cites W2142513160 @default.
- W2013819703 cites W2146111852 @default.
- W2013819703 cites W2152984372 @default.
- W2013819703 cites W2157107389 @default.
- W2013819703 cites W2158157679 @default.
- W2013819703 cites W2158198131 @default.
- W2013819703 cites W2167982785 @default.
- W2013819703 cites W2169366834 @default.
- W2013819703 cites W2170917168 @default.
- W2013819703 cites W2171432898 @default.
- W2013819703 cites W2171563850 @default.
- W2013819703 cites W4241328656 @default.
- W2013819703 cites W4246931769 @default.
- W2013819703 cites W4361807688 @default.
- W2013819703 doi "https://doi.org/10.1128/aem.02763-08" @default.
- W2013819703 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2687275" @default.
- W2013819703 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19346352" @default.
- W2013819703 hasPublicationYear "2009" @default.
- W2013819703 type Work @default.
- W2013819703 sameAs 2013819703 @default.
- W2013819703 citedByCount "78" @default.
- W2013819703 countsByYear W20138197032012 @default.
- W2013819703 countsByYear W20138197032013 @default.
- W2013819703 countsByYear W20138197032014 @default.
- W2013819703 countsByYear W20138197032015 @default.
- W2013819703 countsByYear W20138197032016 @default.
- W2013819703 countsByYear W20138197032017 @default.
- W2013819703 countsByYear W20138197032018 @default.
- W2013819703 countsByYear W20138197032019 @default.
- W2013819703 countsByYear W20138197032020 @default.
- W2013819703 countsByYear W20138197032021 @default.
- W2013819703 countsByYear W20138197032022 @default.
- W2013819703 countsByYear W20138197032023 @default.
- W2013819703 crossrefType "journal-article" @default.
- W2013819703 hasAuthorship W2013819703A5040100787 @default.
- W2013819703 hasAuthorship W2013819703A5043169515 @default.
- W2013819703 hasAuthorship W2013819703A5056199248 @default.
- W2013819703 hasBestOaLocation W20138197031 @default.
- W2013819703 hasConcept C104317684 @default.
- W2013819703 hasConcept C199343813 @default.
- W2013819703 hasConcept C2779914569 @default.
- W2013819703 hasConcept C2780385504 @default.
- W2013819703 hasConcept C2910160754 @default.
- W2013819703 hasConcept C2986629439 @default.
- W2013819703 hasConcept C2992452445 @default.
- W2013819703 hasConcept C42062724 @default.
- W2013819703 hasConcept C504460877 @default.
- W2013819703 hasConcept C54355233 @default.
- W2013819703 hasConcept C55493867 @default.
- W2013819703 hasConcept C71924100 @default.
- W2013819703 hasConcept C86803240 @default.
- W2013819703 hasConcept C89423630 @default.
- W2013819703 hasConcept C91066513 @default.
- W2013819703 hasConceptScore W2013819703C104317684 @default.
- W2013819703 hasConceptScore W2013819703C199343813 @default.
- W2013819703 hasConceptScore W2013819703C2779914569 @default.
- W2013819703 hasConceptScore W2013819703C2780385504 @default.
- W2013819703 hasConceptScore W2013819703C2910160754 @default.
- W2013819703 hasConceptScore W2013819703C2986629439 @default.
- W2013819703 hasConceptScore W2013819703C2992452445 @default.
- W2013819703 hasConceptScore W2013819703C42062724 @default.
- W2013819703 hasConceptScore W2013819703C504460877 @default.
- W2013819703 hasConceptScore W2013819703C54355233 @default.