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- W2013822929 abstract "The development of high brightness and short pulse width (< 200 picoseconds) x-ray lasers now offers biologists the possibility of high-resolution imaging of specimens in an aqueous environment without the blurring effects associated with natural motions and chemical erosion. As a step toward developing the capabilities of this type of x-ray microscopy, a tantalum x-ray laser at 44.83 angstrom wavelength was used together with an x-ray zone plate lens to image both unlabeled and selectively gold-labeled dried rat sperm nuclei. The observed images show ∼500 angstrom features, illustrate the importance of x-ray microscopy in determining chemical composition, and provide information about the uniformity of sperm chromatin organization and the extent of sperm chromatin hydration." @default.
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- W2013822929 date "1992-10-09" @default.
- W2013822929 modified "2023-10-09" @default.
- W2013822929 title "X-Ray Laser Microscopy of Rat Sperm Nuclei" @default.
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- W2013822929 doi "https://doi.org/10.1126/science.1411525" @default.
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