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- W2013827497 abstract "Abstract Background and Aim The leaves of Persea americana are used in traditional medicine to treat, allay or prevent some spasm-related disorders, for instance, diarrhoea. The study was aimed at providing the basis for the anti-spastic use of the leaves of P. americana in folk medicine. Methods The chloroform and methanol fractions of the chloroform–methanol extract of the leaves of P. americana were investigated for their qualitative and quantitative phytochemical constituents as well as effects on gastro-intestinal motility (transit) and castor oil-induced intestinal fluid sodium ion (Na+) and potassium ion (K+) concentrations. Results The qualitative and quantitative phytochemical studies of the chloroform and methanol fractions showed the presence and amounts of alkaloids (2.67 ± 0.13% and 2.57 ± 0.06% respectively), flavonoids (3.20 ± 0.17% and 2.95 ± 0.14% respectively), saponins (2.15 ± 0.08% and 2.23 ± 0.09% respectively), tannins (2.48 ± 0.11% and 2.73 ± 0.13% respectively), steroids (1.36 ± 0.04% and 1.10 ± 0.03% respectively), terpenoids, proteins and carbohydrates in both fractions. Fats and oil were present only in the chloroform fraction. At the two doses (100 and 200 mg/kg body weight), the chloroform and methanol fractions produced significant (p Conclusion The results indicate that the chloroform–methanol extract of the leaves of P. americana contains compounds with anti-spastic effect." @default.
- W2013827497 created "2016-06-24" @default.
- W2013827497 creator A5086809471 @default.
- W2013827497 date "2013-03-01" @default.
- W2013827497 modified "2023-09-26" @default.
- W2013827497 title "Anti-motility and reductions in the concentrations of gut electrolytes: Bases for the anti-spastic use of the leaves of Persea americana in folk medicine" @default.
- W2013827497 cites W2014054409 @default.
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- W2013827497 doi "https://doi.org/10.1016/j.jopr.2013.03.013" @default.
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