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- W2013842666 endingPage "279" @default.
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- W2013842666 abstract "Platelet storage and availability for the purposes of transfusion are currently restricted by a markedly short shelf life of 5 to 7 days owing to an increased risk of bacterial growth and storage-related deterioration called the platelet storage lesion. Because most bacteria grow to confluence within 5 days during storage at room temperature, there is little increased risk of bacterial overgrowth with testing in place, and the only remaining issue is the quality of platelets during the extended storage. Although the manifestations of the storage lesion have been well studied using a variety of in vitro measures, the precise biochemical pathways involved in the initiation and progression of this process have yet to be identified. Proteomics has emerged as a powerful tool to identify and monitor changes during platelet storage and, in combination with biochemical and physiologic studies, facilitates the development of a sophisticated mechanistic view. In this review, we summarize recent experimental work that has led to a detailed overview of protein changes linked to platelet functions and signaling pathways, providing potential targets for inhibitors to ameliorate the storage lesion." @default.
- W2013842666 created "2016-06-24" @default.
- W2013842666 creator A5006207744 @default.
- W2013842666 creator A5009219737 @default.
- W2013842666 creator A5010140123 @default.
- W2013842666 date "2008-10-01" @default.
- W2013842666 modified "2023-09-25" @default.
- W2013842666 title "Platelet Storage Lesion: A New Understanding From a Proteomic Perspective" @default.
- W2013842666 cites W1500447113 @default.
- W2013842666 cites W1519061284 @default.
- W2013842666 cites W1590962651 @default.
- W2013842666 cites W180958031 @default.
- W2013842666 cites W1964502791 @default.
- W2013842666 cites W1964548815 @default.
- W2013842666 cites W1966830640 @default.
- W2013842666 cites W1967772045 @default.
- W2013842666 cites W1971857408 @default.
- W2013842666 cites W1975558168 @default.
- W2013842666 cites W1976160855 @default.
- W2013842666 cites W1976820111 @default.
- W2013842666 cites W1976927239 @default.
- W2013842666 cites W1979829974 @default.
- W2013842666 cites W1980988137 @default.
- W2013842666 cites W1981131409 @default.
- W2013842666 cites W1981244254 @default.
- W2013842666 cites W1981258266 @default.
- W2013842666 cites W1981832206 @default.
- W2013842666 cites W1982157617 @default.
- W2013842666 cites W1983375186 @default.
- W2013842666 cites W1985947600 @default.
- W2013842666 cites W1989468901 @default.
- W2013842666 cites W1992599900 @default.
- W2013842666 cites W1993445266 @default.
- W2013842666 cites W1993589311 @default.
- W2013842666 cites W1994463091 @default.
- W2013842666 cites W1994768909 @default.
- W2013842666 cites W1995304960 @default.
- W2013842666 cites W1998176953 @default.
- W2013842666 cites W2001620341 @default.
- W2013842666 cites W2010110152 @default.
- W2013842666 cites W2011702935 @default.
- W2013842666 cites W2013010104 @default.
- W2013842666 cites W2015095513 @default.
- W2013842666 cites W2017683223 @default.
- W2013842666 cites W2020960046 @default.
- W2013842666 cites W2021000992 @default.
- W2013842666 cites W2026471944 @default.
- W2013842666 cites W2027707342 @default.
- W2013842666 cites W2028714887 @default.
- W2013842666 cites W2030423714 @default.
- W2013842666 cites W2030611695 @default.
- W2013842666 cites W2030938356 @default.
- W2013842666 cites W2032504685 @default.
- W2013842666 cites W2033901564 @default.
- W2013842666 cites W2036945446 @default.
- W2013842666 cites W2037493963 @default.
- W2013842666 cites W2038317295 @default.
- W2013842666 cites W2039639830 @default.
- W2013842666 cites W2039640090 @default.
- W2013842666 cites W2041118362 @default.
- W2013842666 cites W2041340494 @default.
- W2013842666 cites W2043704659 @default.
- W2013842666 cites W2045682687 @default.
- W2013842666 cites W2048678109 @default.
- W2013842666 cites W2049237667 @default.
- W2013842666 cites W2054541525 @default.
- W2013842666 cites W2055415719 @default.
- W2013842666 cites W2055994149 @default.
- W2013842666 cites W2064855362 @default.
- W2013842666 cites W2067465736 @default.
- W2013842666 cites W2072826918 @default.
- W2013842666 cites W2075682724 @default.
- W2013842666 cites W2075736204 @default.
- W2013842666 cites W2076172418 @default.
- W2013842666 cites W2079078985 @default.
- W2013842666 cites W2079584452 @default.
- W2013842666 cites W2079835577 @default.
- W2013842666 cites W2080565891 @default.
- W2013842666 cites W2081933881 @default.
- W2013842666 cites W2083555181 @default.
- W2013842666 cites W2086847463 @default.
- W2013842666 cites W2089104236 @default.
- W2013842666 cites W2089660856 @default.
- W2013842666 cites W2091226453 @default.
- W2013842666 cites W2092844083 @default.
- W2013842666 cites W2093735882 @default.
- W2013842666 cites W2099074476 @default.
- W2013842666 cites W2100124283 @default.
- W2013842666 cites W2103601402 @default.
- W2013842666 cites W2108928365 @default.
- W2013842666 cites W2114315172 @default.
- W2013842666 cites W2114472741 @default.
- W2013842666 cites W2116985222 @default.
- W2013842666 cites W2118520252 @default.
- W2013842666 cites W2122460910 @default.
- W2013842666 cites W2123823902 @default.
- W2013842666 cites W2124338926 @default.
- W2013842666 cites W2125176004 @default.