Matches in SemOpenAlex for { <https://semopenalex.org/work/W2013852596> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W2013852596 endingPage "13" @default.
- W2013852596 startingPage "9" @default.
- W2013852596 abstract "Drug elimination in patients sustaining serious thermal injury may be altered, resulting in an increased clearance and shortened half-life. Nine burn and eight medical/surgical patients with normal renal function were studied prospectively. Doses were adjusted to achieve peak and trough vancomycin serum concentrations within a narrow range. No significant difference between the groups was noted in terms of demographic characteristics, creatinine clearance, or vancomycin serum concentrations. However, the difference in daily dose needed to maintain the specified serum concentrations was significantly greater for burn patients (p less than 0.02). Burn patients also had to be dosed significantly more often than medical/surgical patients to achieve peak and trough vancomycin serum concentrations within the desired range (p less than 0.02). The elimination half-life in burn patients was significantly shorter than that in control patients (p less than 0.001). Because of the unusually high dosage requirements in burn patients, along with their poor predictability, individualization of therapy with vancomycin serum concentrations is recommended to ensure a successful therapeutic outcome." @default.
- W2013852596 created "2016-06-24" @default.
- W2013852596 creator A5053632140 @default.
- W2013852596 creator A5072154163 @default.
- W2013852596 date "1988-07-01" @default.
- W2013852596 modified "2023-10-03" @default.
- W2013852596 title "Altered vancomycin dose vs. serum concentration relationship in burn patients" @default.
- W2013852596 doi "https://doi.org/10.1038/clpt.1988.105" @default.
- W2013852596 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3292106" @default.
- W2013852596 hasPublicationYear "1988" @default.
- W2013852596 type Work @default.
- W2013852596 sameAs 2013852596 @default.
- W2013852596 citedByCount "60" @default.
- W2013852596 countsByYear W20138525962012 @default.
- W2013852596 countsByYear W20138525962013 @default.
- W2013852596 countsByYear W20138525962014 @default.
- W2013852596 countsByYear W20138525962015 @default.
- W2013852596 countsByYear W20138525962018 @default.
- W2013852596 countsByYear W20138525962019 @default.
- W2013852596 countsByYear W20138525962022 @default.
- W2013852596 crossrefType "journal-article" @default.
- W2013852596 hasAuthorship W2013852596A5053632140 @default.
- W2013852596 hasAuthorship W2013852596A5072154163 @default.
- W2013852596 hasConcept C126322002 @default.
- W2013852596 hasConcept C126894567 @default.
- W2013852596 hasConcept C141071460 @default.
- W2013852596 hasConcept C159641895 @default.
- W2013852596 hasConcept C19831878 @default.
- W2013852596 hasConcept C2777288759 @default.
- W2013852596 hasConcept C2778980435 @default.
- W2013852596 hasConcept C2779489039 @default.
- W2013852596 hasConcept C2780035454 @default.
- W2013852596 hasConcept C2780306776 @default.
- W2013852596 hasConcept C2910800852 @default.
- W2013852596 hasConcept C3020081911 @default.
- W2013852596 hasConcept C42219234 @default.
- W2013852596 hasConcept C523546767 @default.
- W2013852596 hasConcept C54355233 @default.
- W2013852596 hasConcept C71924100 @default.
- W2013852596 hasConcept C86803240 @default.
- W2013852596 hasConcept C98274493 @default.
- W2013852596 hasConceptScore W2013852596C126322002 @default.
- W2013852596 hasConceptScore W2013852596C126894567 @default.
- W2013852596 hasConceptScore W2013852596C141071460 @default.
- W2013852596 hasConceptScore W2013852596C159641895 @default.
- W2013852596 hasConceptScore W2013852596C19831878 @default.
- W2013852596 hasConceptScore W2013852596C2777288759 @default.
- W2013852596 hasConceptScore W2013852596C2778980435 @default.
- W2013852596 hasConceptScore W2013852596C2779489039 @default.
- W2013852596 hasConceptScore W2013852596C2780035454 @default.
- W2013852596 hasConceptScore W2013852596C2780306776 @default.
- W2013852596 hasConceptScore W2013852596C2910800852 @default.
- W2013852596 hasConceptScore W2013852596C3020081911 @default.
- W2013852596 hasConceptScore W2013852596C42219234 @default.
- W2013852596 hasConceptScore W2013852596C523546767 @default.
- W2013852596 hasConceptScore W2013852596C54355233 @default.
- W2013852596 hasConceptScore W2013852596C71924100 @default.
- W2013852596 hasConceptScore W2013852596C86803240 @default.
- W2013852596 hasConceptScore W2013852596C98274493 @default.
- W2013852596 hasIssue "1" @default.
- W2013852596 hasLocation W20138525961 @default.
- W2013852596 hasLocation W20138525962 @default.
- W2013852596 hasOpenAccess W2013852596 @default.
- W2013852596 hasPrimaryLocation W20138525961 @default.
- W2013852596 hasRelatedWork W1534257421 @default.
- W2013852596 hasRelatedWork W1892965049 @default.
- W2013852596 hasRelatedWork W2077750458 @default.
- W2013852596 hasRelatedWork W2099531681 @default.
- W2013852596 hasRelatedWork W2109792151 @default.
- W2013852596 hasRelatedWork W2154361835 @default.
- W2013852596 hasRelatedWork W2160515228 @default.
- W2013852596 hasRelatedWork W2170749810 @default.
- W2013852596 hasRelatedWork W2289534228 @default.
- W2013852596 hasRelatedWork W2899408284 @default.
- W2013852596 hasVolume "44" @default.
- W2013852596 isParatext "false" @default.
- W2013852596 isRetracted "false" @default.
- W2013852596 magId "2013852596" @default.
- W2013852596 workType "article" @default.