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- W2013853357 abstract "One anticapsid (p26) mouse monoclonal antibody was developed after immunization with recombinant p26 Gag protein and was tested for reactivity with different HIV-1 and HIV-2 isolates by ELISA and Western blot analysis. This antibody, named R26.1, reacted with all HIV-2 isolates tested and with recombinant p26 proteins, but no HIV-1 isolates. The epitope of antibody R26.1 was mapped to residues 50-71 in the N-terminal domain of the capsid protein, a highly conserved region in all HIV-2 isolates sequenced to date. This monoclonal antibody may be useful for the detection of HIV-2, and for the discrimination between HIV-1 and HIV-2 infections. Likewise, the identified epitope may be useful for the detection of p26 antibodies in HIV-2-infected individuals." @default.
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- W2013853357 date "2001-09-01" @default.
- W2013853357 modified "2023-10-01" @default.
- W2013853357 title "Production and Characterization of a Mouse Monoclonal Antibody against the Gag p26 Protein of Human Immunodeficiency Virus Type 2: Identification of a New Antigenic Epitope" @default.
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- W2013853357 doi "https://doi.org/10.1089/088922201750461348" @default.
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