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- W2013867105 abstract "Serum C-peptide levels were measured during a glucagon stimulation test in ten normal nonobese controls and 54 diabetic patients with recent onset of diabetes under 30 years of age. Diabetic patients were comprised of 13 CTPD, 23 IDDM, and 18 NIDDM. As similar to IDDM patients, serum C-peptide concentrations did not rise significantly (P > 0.05) in response to glucagon administration in CTPD-patients. Mean baseline and peak serum C-peptide concentrations in CTPD-patients were significantly lower (P < 0.001) than the values in normal controls and NIDDM patients, but were significantly higher (P < 0.05) than those in IDDM patients. We conclude that CTPD patients have partial C-peptide reserve, which may protect against ketosis and contribute to ketosis resistance in CTPD. Our results also suggest that CTPD patients require insulin treatment. Neither baseline nor peak C-peptide levels after glucagon could discriminate CTPD from IDDM and CTPD from NIDDM." @default.
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- W2013867105 date "1986-09-01" @default.
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- W2013867105 title "C-peptide secretion in calcific tropical pancreatic diabetes" @default.
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- W2013867105 doi "https://doi.org/10.1016/0026-0495(86)90221-0" @default.
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