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• W2013871444 abstract "In this study, solid dispersion systems of the sparingly water soluble drug, albendazole (ABZ), were mixed with varying concentrations of polyvinylpyrrolidone (PVP K 12) in an attempt to improve the solubility and dissolution rate of ABZ. Physical characteristics were investigated by Powder X-ray diffraction. As expected, the albendazole dissolution rate, expressed as the dissolution efficiency, and also the solubility coefficient were increased when albendazole was mixed with PVP. An increase in the concentration of the polymer in the solid dispersion produced an increase in both parameters. The powder X-ray diffraction patterns showed that the solid dispersion presented an amorphous form of albendazole in this coprecipitate system." @default.
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• W2013871444 date "1996-08-01" @default.
• W2013871444 modified "2023-10-03" @default.
• W2013871444 title "Preparation, dissolution and characterization of albendazole solid dispersions" @default.
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• W2013871444 doi "https://doi.org/10.1016/0378-5173(96)04586-3" @default.
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