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- W2013929241 abstract "Chicken antibodies raised to the (Fab')2 fragment of mouse IgG recognize determinants expressed on both normal mouse serum and T-cell-associated immunoglobulin, as assessed by immune diffusion and competition radioimmunoassay. Analyses of reactions with both normal and myeloma immunoglobulins indicate that chicken anti-(Fab')2 recognizes determinants expressed on light and heavy (Fd fragment) chains of mouse IgG and IgM. The relatively low efficiency of reaction of purified γ heavy and light chains (compared to intact IgG) with the anti-(Fab')2 suggests that these antibodies recognize determinants expressed only when heavy and light chains are combined in the native molecule. Serological studies with T-cell-associated immunoglobulin show that this molecule expresses determinants cross-reactive with both light and heavy immunoglobulin polypeptide chains. The antigenic determinants seen on the T-cell immunoglobulin light and heavy chains are common to IgM and IgG and are not isotype specific." @default.
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- W2013929241 date "1978-08-01" @default.
- W2013929241 modified "2023-09-25" @default.
- W2013929241 title "Reactions of chicken antibodies with immunoglobulins of mouse serum and T cells" @default.
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- W2013929241 doi "https://doi.org/10.1016/0161-5890(78)90033-0" @default.
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