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- W2013967178 abstract "Antiidiotypic approach was used to obtain antibodies interacting with cGMP-binding site of the cGMP-activated channel of the photoreceptor cell. Monoclonal anti-BrcGMP antibodies having characteristics of binding of agonist and its analogs close to those for a natural receptor have been obtained. These antibodies were used to raise polyclonal antiidiotypic antibodies capable of interacting with a natural cGMP-receptor. Application of immunoglobulins, isolated from antiidiotypic serum, to inside-out fragments of the rod plasma membrane led to an irreversible increase of the conductance of cGMP-dependent channels." @default.
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- W2013967178 date "1991-01-01" @default.
- W2013967178 modified "2023-09-25" @default.
- W2013967178 title "Antiidiotypic Antibodies Interacting with cGMP-Dependent Channels of Frog Retinal Rod Outer Segments" @default.
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- W2013967178 doi "https://doi.org/10.3109/10799899109064678" @default.
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