Matches in SemOpenAlex for { <https://semopenalex.org/work/W2013993334> ?p ?o ?g. }
- W2013993334 endingPage "987" @default.
- W2013993334 startingPage "978" @default.
- W2013993334 abstract "To investigate the role of macrophages in the pathogenesis of chronic streptococcal cell wall (SCW)-induced arthritis using liposomal clodronate.Female Lewis rats with SCW-induced arthritis received a single intravenous injection of 20 mg of clodronate encapsulated within small unilamellar vesicles (SUVc) 10 days post-arthritis induction.SUVc significantly suppressed the development of chronic SCW-induced arthritis for up to 26 days after treatment. At this time point, ED1(+) macrophages were significantly depleted in the liver and ankle joints, although splenic macrophage numbers were not significantly different from control groups. Macrophage elimination induced a significant reduction in local levels of interleukin (IL)-1beta, IL-6, tumour necrosis factor-alpha (TNFalpha) and matrix metalloproteinase-9 (MMP-9) from ankle joints.Macrophage elimination by SUVc inhibits local production of IL-1beta, IL-6, TNFalpha and MMP-9, and the pathogenesis of inflammatory arthritis." @default.
- W2013993334 created "2016-06-24" @default.
- W2013993334 creator A5004461863 @default.
- W2013993334 creator A5010122389 @default.
- W2013993334 creator A5028429978 @default.
- W2013993334 date "2001-09-01" @default.
- W2013993334 modified "2023-10-17" @default.
- W2013993334 title "Suppression of chronic streptococcal cell wall‐induced arthritis in Lewis rats by liposomal clodronate" @default.
- W2013993334 cites W1930529657 @default.
- W2013993334 cites W1948756029 @default.
- W2013993334 cites W1949660292 @default.
- W2013993334 cites W1964756939 @default.
- W2013993334 cites W1967028286 @default.
- W2013993334 cites W1971684738 @default.
- W2013993334 cites W1978103379 @default.
- W2013993334 cites W1983316933 @default.
- W2013993334 cites W1985444803 @default.
- W2013993334 cites W1994723172 @default.
- W2013993334 cites W1996794055 @default.
- W2013993334 cites W2001455948 @default.
- W2013993334 cites W2001660220 @default.
- W2013993334 cites W2009140782 @default.
- W2013993334 cites W2009216080 @default.
- W2013993334 cites W2019737992 @default.
- W2013993334 cites W2025047599 @default.
- W2013993334 cites W2026007132 @default.
- W2013993334 cites W2026342001 @default.
- W2013993334 cites W2026491444 @default.
- W2013993334 cites W2031912912 @default.
- W2013993334 cites W2035274828 @default.
- W2013993334 cites W2037950123 @default.
- W2013993334 cites W2041535822 @default.
- W2013993334 cites W2047365388 @default.
- W2013993334 cites W2054965467 @default.
- W2013993334 cites W2058267243 @default.
- W2013993334 cites W2087992995 @default.
- W2013993334 cites W2101035519 @default.
- W2013993334 cites W2102938005 @default.
- W2013993334 cites W2103391607 @default.
- W2013993334 cites W2103825824 @default.
- W2013993334 cites W2125433561 @default.
- W2013993334 cites W2133437569 @default.
- W2013993334 cites W2139162201 @default.
- W2013993334 cites W2142273705 @default.
- W2013993334 cites W2143939606 @default.
- W2013993334 cites W2150602579 @default.
- W2013993334 cites W2161151160 @default.
- W2013993334 cites W2163275885 @default.
- W2013993334 cites W2164519189 @default.
- W2013993334 cites W2167031471 @default.
- W2013993334 cites W2168037581 @default.
- W2013993334 cites W2321864371 @default.
- W2013993334 cites W4322703114 @default.
- W2013993334 doi "https://doi.org/10.1093/rheumatology/40.9.978" @default.
- W2013993334 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11561107" @default.
- W2013993334 hasPublicationYear "2001" @default.
- W2013993334 type Work @default.
- W2013993334 sameAs 2013993334 @default.
- W2013993334 citedByCount "51" @default.
- W2013993334 countsByYear W20139933342012 @default.
- W2013993334 countsByYear W20139933342013 @default.
- W2013993334 countsByYear W20139933342014 @default.
- W2013993334 countsByYear W20139933342015 @default.
- W2013993334 countsByYear W20139933342016 @default.
- W2013993334 countsByYear W20139933342018 @default.
- W2013993334 countsByYear W20139933342019 @default.
- W2013993334 countsByYear W20139933342020 @default.
- W2013993334 countsByYear W20139933342021 @default.
- W2013993334 crossrefType "journal-article" @default.
- W2013993334 hasAuthorship W2013993334A5004461863 @default.
- W2013993334 hasAuthorship W2013993334A5010122389 @default.
- W2013993334 hasAuthorship W2013993334A5028429978 @default.
- W2013993334 hasBestOaLocation W20139933341 @default.
- W2013993334 hasConcept C109523444 @default.
- W2013993334 hasConcept C126322002 @default.
- W2013993334 hasConcept C17991360 @default.
- W2013993334 hasConcept C185592680 @default.
- W2013993334 hasConcept C202751555 @default.
- W2013993334 hasConcept C203014093 @default.
- W2013993334 hasConcept C2777077863 @default.
- W2013993334 hasConcept C2777575956 @default.
- W2013993334 hasConcept C2779244956 @default.
- W2013993334 hasConcept C2780942790 @default.
- W2013993334 hasConcept C503630168 @default.
- W2013993334 hasConcept C55493867 @default.
- W2013993334 hasConcept C71924100 @default.
- W2013993334 hasConceptScore W2013993334C109523444 @default.
- W2013993334 hasConceptScore W2013993334C126322002 @default.
- W2013993334 hasConceptScore W2013993334C17991360 @default.
- W2013993334 hasConceptScore W2013993334C185592680 @default.
- W2013993334 hasConceptScore W2013993334C202751555 @default.
- W2013993334 hasConceptScore W2013993334C203014093 @default.
- W2013993334 hasConceptScore W2013993334C2777077863 @default.
- W2013993334 hasConceptScore W2013993334C2777575956 @default.
- W2013993334 hasConceptScore W2013993334C2779244956 @default.
- W2013993334 hasConceptScore W2013993334C2780942790 @default.
- W2013993334 hasConceptScore W2013993334C503630168 @default.
- W2013993334 hasConceptScore W2013993334C55493867 @default.