Matches in SemOpenAlex for { <https://semopenalex.org/work/W2013997922> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2013997922 endingPage "162" @default.
- W2013997922 startingPage "158" @default.
- W2013997922 abstract "Two case reports have cited the recreational use of cocaine as possible trigger of a malignant hyperthermia (MH) crisis. We evaluated whether toxic concentrations of cocaine altered the in vitro muscle response to halothane during contracture tests for MH. Twenty-two patients were studied. Muscle biopsies were obtained and first tested for MH susceptibility with 3% halothane and caffeine contracture testing. Ten patients were diagnosed as MH-susceptible and 12 as MH non-susceptible, in accordance with the North American Malignant Hyperthermia Group protocol. Then, muscle strips were exposed to 1% halothane in the presence and absence of 0.1 mmol.L-1 cocaine. Cocaine alone did not affect baseline muscle tension in either group. With 1% halothane, MH non-susceptible muscle showed no contracture with or without cocaine. In contrast, in the presence of 1% halothane, MH-susceptible muscle showed either no change in contracture (six patients), an increase (two patients), or a decrease (two patients) when exposed to cocaine. However, the overall effect of cocaine on muscle contracture in the presence of 1% halothane was insignificant in both groups. We conclude that cocaine, even at toxic levels, does not have a direct effect on skeletal muscle contractility and thus is safe for MH-susceptible patients." @default.
- W2013997922 created "2016-06-24" @default.
- W2013997922 creator A5001513193 @default.
- W2013997922 creator A5041091037 @default.
- W2013997922 creator A5070593246 @default.
- W2013997922 creator A5074375809 @default.
- W2013997922 date "1995-02-01" @default.
- W2013997922 modified "2023-10-14" @default.
- W2013997922 title "Effect of cocaine on the contracture response to 1% halothane in patients undergoing diagnostic muscle biopsy for malignant hyperthermia" @default.
- W2013997922 cites W1534930018 @default.
- W2013997922 cites W1964544683 @default.
- W2013997922 cites W1970518314 @default.
- W2013997922 cites W1985664113 @default.
- W2013997922 cites W2009671495 @default.
- W2013997922 cites W2024284115 @default.
- W2013997922 cites W2027224915 @default.
- W2013997922 cites W2038788609 @default.
- W2013997922 cites W2040119026 @default.
- W2013997922 cites W2040777570 @default.
- W2013997922 cites W2047044600 @default.
- W2013997922 cites W2056104512 @default.
- W2013997922 cites W2088049415 @default.
- W2013997922 cites W2091685634 @default.
- W2013997922 cites W2105016566 @default.
- W2013997922 cites W2105397287 @default.
- W2013997922 cites W2129460691 @default.
- W2013997922 cites W2130428951 @default.
- W2013997922 cites W2168625096 @default.
- W2013997922 cites W2233475212 @default.
- W2013997922 cites W2398388078 @default.
- W2013997922 cites W4247625354 @default.
- W2013997922 cites W4313371759 @default.
- W2013997922 doi "https://doi.org/10.1007/bf03028270" @default.
- W2013997922 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7720160" @default.
- W2013997922 hasPublicationYear "1995" @default.
- W2013997922 type Work @default.
- W2013997922 sameAs 2013997922 @default.
- W2013997922 citedByCount "6" @default.
- W2013997922 countsByYear W20139979222016 @default.
- W2013997922 countsByYear W20139979222017 @default.
- W2013997922 crossrefType "journal-article" @default.
- W2013997922 hasAuthorship W2013997922A5001513193 @default.
- W2013997922 hasAuthorship W2013997922A5041091037 @default.
- W2013997922 hasAuthorship W2013997922A5070593246 @default.
- W2013997922 hasAuthorship W2013997922A5074375809 @default.
- W2013997922 hasBestOaLocation W20139979221 @default.
- W2013997922 hasConcept C126322002 @default.
- W2013997922 hasConcept C127607297 @default.
- W2013997922 hasConcept C141071460 @default.
- W2013997922 hasConcept C2775934546 @default.
- W2013997922 hasConcept C2776932660 @default.
- W2013997922 hasConcept C2776937108 @default.
- W2013997922 hasConcept C2778575482 @default.
- W2013997922 hasConcept C2779949491 @default.
- W2013997922 hasConcept C2779959927 @default.
- W2013997922 hasConcept C2779999465 @default.
- W2013997922 hasConcept C42219234 @default.
- W2013997922 hasConcept C71924100 @default.
- W2013997922 hasConceptScore W2013997922C126322002 @default.
- W2013997922 hasConceptScore W2013997922C127607297 @default.
- W2013997922 hasConceptScore W2013997922C141071460 @default.
- W2013997922 hasConceptScore W2013997922C2775934546 @default.
- W2013997922 hasConceptScore W2013997922C2776932660 @default.
- W2013997922 hasConceptScore W2013997922C2776937108 @default.
- W2013997922 hasConceptScore W2013997922C2778575482 @default.
- W2013997922 hasConceptScore W2013997922C2779949491 @default.
- W2013997922 hasConceptScore W2013997922C2779959927 @default.
- W2013997922 hasConceptScore W2013997922C2779999465 @default.
- W2013997922 hasConceptScore W2013997922C42219234 @default.
- W2013997922 hasConceptScore W2013997922C71924100 @default.
- W2013997922 hasIssue "2" @default.
- W2013997922 hasLocation W20139979221 @default.
- W2013997922 hasLocation W20139979222 @default.
- W2013997922 hasOpenAccess W2013997922 @default.
- W2013997922 hasPrimaryLocation W20139979221 @default.
- W2013997922 hasRelatedWork W2013997922 @default.
- W2013997922 hasRelatedWork W2018991587 @default.
- W2013997922 hasRelatedWork W2050213576 @default.
- W2013997922 hasRelatedWork W2075430292 @default.
- W2013997922 hasRelatedWork W2133715259 @default.
- W2013997922 hasRelatedWork W2141410793 @default.
- W2013997922 hasRelatedWork W2320881754 @default.
- W2013997922 hasRelatedWork W2397261706 @default.
- W2013997922 hasRelatedWork W2403362729 @default.
- W2013997922 hasRelatedWork W4256237532 @default.
- W2013997922 hasVolume "42" @default.
- W2013997922 isParatext "false" @default.
- W2013997922 isRetracted "false" @default.
- W2013997922 magId "2013997922" @default.
- W2013997922 workType "article" @default.