FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W201399997> ?p ?o ?g. }

• W201399997 abstract "Mice are now the most commonly used animal model for the study of asthma. The mouse asthma model has many characteristics of the human pathology, including allergic sensitization and airway hyperresponsiveness. Inbred strains are commonly used to avoid variations due to genetic background, but variations due to rearing environment are not as well recognized. After a change in mouse vendors and a switch from C57BL/6J mice to C57BL/6N mice, we noted significant differences in airway responsiveness between the substrains. To further investigate the effect of vendor, we tested C57BL/6N mice from 3 other vendors and found significant differences between several of the substrains. To test whether this difference was due to genetic drift or rearing environment, we purchased new groups of mice from all 5 vendors, bred them in separate vendor-specific groups under uniform environmental conditions, and tested male first generation (F1) offspring at 8 to 10 wk of age. These F1 mice showed no significant differences in airway responsiveness, indicating that the rearing environment rather than genetic differences was responsible for the initial variation in pulmonary phenotype. The environmental factors that caused the phenotypic variation are unknown. However, differences between vendor in feed components, bedding type, or microbiome could have contributed. Whatever the basis, investigators using mouse models of asthma should be cautious in comparing data from mice obtained from different vendors." @default.
• W201399997 created "2016-06-24" @default.
• W201399997 creator A5042498348 @default.
• W201399997 creator A5076303344 @default.
• W201399997 creator A5086384405 @default.
• W201399997 date "2012-07-01" @default.
• W201399997 modified "2023-10-03" @default.
• W201399997 title "Variation in airway responsiveness of male C57BL/6 mice from 5 vendors." @default.
• W201399997 cites W1498671792 @default.
• W201399997 cites W1513759662 @default.
• W201399997 cites W1522613673 @default.
• W201399997 cites W1570602560 @default.
• W201399997 cites W1595623223 @default.
• W201399997 cites W1614317053 @default.
• W201399997 cites W1919239301 @default.
• W201399997 cites W1940416395 @default.
• W201399997 cites W1974163512 @default.
• W201399997 cites W1974485146 @default.
• W201399997 cites W1985995428 @default.
• W201399997 cites W1988513230 @default.
• W201399997 cites W2002953403 @default.
• W201399997 cites W2004774344 @default.
• W201399997 cites W2024225734 @default.
• W201399997 cites W2027216673 @default.
• W201399997 cites W2027937017 @default.
• W201399997 cites W2029707852 @default.
• W201399997 cites W2034154612 @default.
• W201399997 cites W2037671283 @default.
• W201399997 cites W2050872483 @default.
• W201399997 cites W2102108747 @default.
• W201399997 cites W2103154415 @default.
• W201399997 cites W2107369528 @default.
• W201399997 cites W2109958057 @default.
• W201399997 cites W2110548786 @default.
• W201399997 cites W2127361574 @default.
• W201399997 cites W2127854030 @default.
• W201399997 cites W2128704622 @default.
• W201399997 cites W2132701025 @default.
• W201399997 cites W2140066355 @default.
• W201399997 cites W2143325745 @default.
• W201399997 cites W2152609359 @default.
• W201399997 cites W2169343837 @default.
• W201399997 cites W2171401199 @default.
• W201399997 cites W2189257806 @default.
• W201399997 cites W2412133054 @default.
• W201399997 cites W27326414 @default.
• W201399997 cites W68080539 @default.
• W201399997 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3400687" @default.
• W201399997 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23043804" @default.
• W201399997 hasPublicationYear "2012" @default.
• W201399997 type Work @default.
• W201399997 sameAs 201399997 @default.
• W201399997 citedByCount "18" @default.
• W201399997 countsByYear W2013999972014 @default.
• W201399997 countsByYear W2013999972015 @default.
• W201399997 countsByYear W2013999972016 @default.
• W201399997 countsByYear W2013999972017 @default.
• W201399997 countsByYear W2013999972018 @default.
• W201399997 countsByYear W2013999972019 @default.
• W201399997 countsByYear W2013999972020 @default.
• W201399997 countsByYear W2013999972021 @default.
• W201399997 countsByYear W2013999972023 @default.
• W201399997 crossrefType "journal-article" @default.
• W201399997 hasAuthorship W201399997A5042498348 @default.
• W201399997 hasAuthorship W201399997A5076303344 @default.
• W201399997 hasAuthorship W201399997A5086384405 @default.
• W201399997 hasConcept C104317684 @default.
• W201399997 hasConcept C105922876 @default.
• W201399997 hasConcept C112672928 @default.
• W201399997 hasConcept C127716648 @default.
• W201399997 hasConcept C134018914 @default.
• W201399997 hasConcept C141071460 @default.
• W201399997 hasConcept C144133560 @default.
• W201399997 hasConcept C162853370 @default.
• W201399997 hasConcept C203014093 @default.
• W201399997 hasConcept C2776042228 @default.
• W201399997 hasConcept C2776217527 @default.
• W201399997 hasConcept C2777338717 @default.
• W201399997 hasConcept C2778117688 @default.
• W201399997 hasConcept C2779234561 @default.
• W201399997 hasConcept C2779456560 @default.
• W201399997 hasConcept C3019828301 @default.
• W201399997 hasConcept C42407357 @default.
• W201399997 hasConcept C54355233 @default.
• W201399997 hasConcept C71924100 @default.
• W201399997 hasConcept C76725341 @default.
• W201399997 hasConcept C86803240 @default.
• W201399997 hasConceptScore W201399997C104317684 @default.
• W201399997 hasConceptScore W201399997C105922876 @default.
• W201399997 hasConceptScore W201399997C112672928 @default.
• W201399997 hasConceptScore W201399997C127716648 @default.
• W201399997 hasConceptScore W201399997C134018914 @default.
• W201399997 hasConceptScore W201399997C141071460 @default.
• W201399997 hasConceptScore W201399997C144133560 @default.
• W201399997 hasConceptScore W201399997C162853370 @default.
• W201399997 hasConceptScore W201399997C203014093 @default.
• W201399997 hasConceptScore W201399997C2776042228 @default.
• W201399997 hasConceptScore W201399997C2776217527 @default.
• W201399997 hasConceptScore W201399997C2777338717 @default.
• W201399997 hasConceptScore W201399997C2778117688 @default.

• next