FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014016927> ?p ?o ?g. }

• W2014016927 endingPage "423" @default.
• W2014016927 startingPage "413" @default.
• W2014016927 abstract "Understanding cognitive aging is becoming more important as the elderly population grows. Here, the effects of age and sex on learning and memory performance were compared in female and male young (3–4 months old) middle-aged (10–12 months old) and old (18–20 months old) wild-type C57BL/6J mice. Old males and females performed worse than young or middle-aged mice in novel location, but not novel object recognition tasks. Old mice, of both sexes, also showed impaired spatial water maze performance during training compared with young or middle-aged mice, however only old females failed to show robust spatial bias during probe trials. While there was no age-difference in passive avoidance performance for males, females showed an age-related decline. There was no difference in cognitive performance between young and middle-age mice of either sex on any task. Cognitive performance was associated with alterations in immunoreactivity of microtubule-associated protein 2-positive dendrites and synaptophysin-positive pre-synaptic terminals in hippocampal CA1, CA3, and dentate, entorhinal cortex, and central nucleus of amygdala. Overall, microtubule-associated protein 2 immunoreactivity was increased in old females compared with both young and middle-age females with no significant difference in males. In contrast, synaptophysin immunoreactivity increased from young to middle-age in females, and from middle-age to old in males; females had higher levels of synaptophysin immunoreactivity than males in middle-age only. Elevated levels of microtubule-associated protein 2 and synaptophysin may constitute a compensatory response to age-related functional decline in mice." @default.
• W2014016927 created "2016-06-24" @default.
• W2014016927 creator A5012586996 @default.
• W2014016927 creator A5029979625 @default.
• W2014016927 creator A5049562137 @default.
• W2014016927 creator A5053483546 @default.
• W2014016927 creator A5057286291 @default.
• W2014016927 date "2006-01-01" @default.
• W2014016927 modified "2023-10-13" @default.
• W2014016927 title "Sex-differences in age-related cognitive decline in C57BL/6J mice associated with increased brain microtubule-associated protein 2 and synaptophysin immunoreactivity" @default.
• W2014016927 cites W111949188 @default.
• W2014016927 cites W1929729372 @default.
• W2014016927 cites W1963097925 @default.
• W2014016927 cites W1987580992 @default.
• W2014016927 cites W1996815356 @default.
• W2014016927 cites W2006129024 @default.
• W2014016927 cites W2010351278 @default.
• W2014016927 cites W2011850678 @default.
• W2014016927 cites W2017169966 @default.
• W2014016927 cites W2018873431 @default.
• W2014016927 cites W2020949930 @default.
• W2014016927 cites W2024287605 @default.
• W2014016927 cites W2024791530 @default.
• W2014016927 cites W2027397361 @default.
• W2014016927 cites W2028003385 @default.
• W2014016927 cites W2035986405 @default.
• W2014016927 cites W2037387044 @default.
• W2014016927 cites W2038218988 @default.
• W2014016927 cites W2043084329 @default.
• W2014016927 cites W2058970680 @default.
• W2014016927 cites W2059215368 @default.
• W2014016927 cites W2062060338 @default.
• W2014016927 cites W2067260963 @default.
• W2014016927 cites W2067541453 @default.
• W2014016927 cites W2081095372 @default.
• W2014016927 cites W2085322382 @default.
• W2014016927 cites W2088993406 @default.
• W2014016927 cites W2089715790 @default.
• W2014016927 cites W2090990702 @default.
• W2014016927 cites W2094311708 @default.
• W2014016927 cites W2095436346 @default.
• W2014016927 cites W2114589445 @default.
• W2014016927 cites W2114597265 @default.
• W2014016927 cites W2116878354 @default.
• W2014016927 cites W2117522169 @default.
• W2014016927 cites W2129678592 @default.
• W2014016927 cites W2137007429 @default.
• W2014016927 cites W2142651501 @default.
• W2014016927 cites W2153799996 @default.
• W2014016927 cites W2165050788 @default.
• W2014016927 cites W4248408063 @default.
• W2014016927 cites W4301315920 @default.
• W2014016927 cites W4366064872 @default.
• W2014016927 cites W54430093 @default.
• W2014016927 doi "https://doi.org/10.1016/j.neuroscience.2005.08.029" @default.
• W2014016927 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16330151" @default.
• W2014016927 hasPublicationYear "2006" @default.
• W2014016927 type Work @default.
• W2014016927 sameAs 2014016927 @default.
• W2014016927 citedByCount "209" @default.
• W2014016927 countsByYear W20140169272012 @default.
• W2014016927 countsByYear W20140169272013 @default.
• W2014016927 countsByYear W20140169272014 @default.
• W2014016927 countsByYear W20140169272015 @default.
• W2014016927 countsByYear W20140169272016 @default.
• W2014016927 countsByYear W20140169272017 @default.
• W2014016927 countsByYear W20140169272018 @default.
• W2014016927 countsByYear W20140169272019 @default.
• W2014016927 countsByYear W20140169272020 @default.
• W2014016927 countsByYear W20140169272021 @default.
• W2014016927 countsByYear W20140169272022 @default.
• W2014016927 countsByYear W20140169272023 @default.
• W2014016927 crossrefType "journal-article" @default.
• W2014016927 hasAuthorship W2014016927A5012586996 @default.
• W2014016927 hasAuthorship W2014016927A5029979625 @default.
• W2014016927 hasAuthorship W2014016927A5049562137 @default.
• W2014016927 hasAuthorship W2014016927A5053483546 @default.
• W2014016927 hasAuthorship W2014016927A5057286291 @default.
• W2014016927 hasConcept C126322002 @default.
• W2014016927 hasConcept C134018914 @default.
• W2014016927 hasConcept C148762608 @default.
• W2014016927 hasConcept C15744967 @default.
• W2014016927 hasConcept C169760540 @default.
• W2014016927 hasConcept C204232928 @default.
• W2014016927 hasConcept C2777209535 @default.
• W2014016927 hasConcept C2779134260 @default.
• W2014016927 hasConcept C2779483572 @default.
• W2014016927 hasConcept C2779758577 @default.
• W2014016927 hasConcept C2780715579 @default.
• W2014016927 hasConcept C2781161787 @default.
• W2014016927 hasConcept C2908647359 @default.
• W2014016927 hasConcept C2984863031 @default.
• W2014016927 hasConcept C71924100 @default.
• W2014016927 hasConcept C86803240 @default.
• W2014016927 hasConcept C99454951 @default.
• W2014016927 hasConceptScore W2014016927C126322002 @default.
• W2014016927 hasConceptScore W2014016927C134018914 @default.
• W2014016927 hasConceptScore W2014016927C148762608 @default.

• next