FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014019086> ?p ?o ?g. }

• W2014019086 endingPage "97" @default.
• W2014019086 startingPage "91" @default.
• W2014019086 abstract "Ethidium bromide (EtBr) and SYBR Green I are nucleic acid gel stains and used commonly in combination with UV-illumination. EtBr preferentially induces frameshift mutations but only in the presence of an exogenous metabolic activation system, while SYBR Green I is a very weak mutagen that induces frameshift mutations. We found that EtBr and SYBR Green I, without an added metabolic activation system, strongly potentiated the base-substitution mutations induced by UV-irradiation in E. coli B/r WP2 cells. Each DNA stain alone showed no mutagenicity to the strain. Base-substitutions induced by 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX) and 4-nitroquinoline-1-oxide were similarly potentiated by EtBr and SYBR Green I. SYBR Green I had a much greater effect. No enhancing effects were observed on mutations induced by mitomycin C, cisplatin, transplatin, cumene hydroperoxide, base analogs, and alkylating agents. Another DNA stain, acridine orange, showed similar enhancing effects on UV- and MX-mutagenicity, but no effect was observed for 4',6-diamidino-2-phenylindole (DAPI). UV- and MX-induced mutations in E. coli WP2s (uvrA), which is defective in nucleotide excision repair activity, were not potentiated by the addition of EtBr, SYBR Green I, or acridine orange. Those nucleic acid stains might inhibit the nucleotide excision repair of DNA damaged by UV and MX treatment." @default.
• W2014019086 created "2016-06-24" @default.
• W2014019086 creator A5013561411 @default.
• W2014019086 creator A5051514780 @default.
• W2014019086 creator A5076286709 @default.
• W2014019086 date "2001-05-01" @default.
• W2014019086 modified "2023-09-27" @default.
• W2014019086 title "Ethidium bromide and SYBR Green I enhance the genotoxicity of UV-irradiation and chemical mutagens in E. coli" @default.
• W2014019086 cites W1967054692 @default.
• W2014019086 cites W1969134299 @default.
• W2014019086 cites W1976917904 @default.
• W2014019086 cites W1985000280 @default.
• W2014019086 cites W1992113844 @default.
• W2014019086 cites W2005156172 @default.
• W2014019086 cites W2006082799 @default.
• W2014019086 cites W2012236032 @default.
• W2014019086 cites W2021275486 @default.
• W2014019086 cites W2044318965 @default.
• W2014019086 cites W2052373946 @default.
• W2014019086 cites W2064022487 @default.
• W2014019086 cites W2077303224 @default.
• W2014019086 cites W2084261443 @default.
• W2014019086 cites W2103503554 @default.
• W2014019086 cites W2130592210 @default.
• W2014019086 doi "https://doi.org/10.1016/s1383-5718(01)00155-3" @default.
• W2014019086 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11377248" @default.
• W2014019086 hasPublicationYear "2001" @default.
• W2014019086 type Work @default.
• W2014019086 sameAs 2014019086 @default.
• W2014019086 citedByCount "58" @default.
• W2014019086 countsByYear W20140190862012 @default.
• W2014019086 countsByYear W20140190862013 @default.
• W2014019086 countsByYear W20140190862014 @default.
• W2014019086 countsByYear W20140190862015 @default.
• W2014019086 countsByYear W20140190862016 @default.
• W2014019086 countsByYear W20140190862017 @default.
• W2014019086 countsByYear W20140190862018 @default.
• W2014019086 countsByYear W20140190862019 @default.
• W2014019086 countsByYear W20140190862020 @default.
• W2014019086 countsByYear W20140190862021 @default.
• W2014019086 countsByYear W20140190862022 @default.
• W2014019086 countsByYear W20140190862023 @default.
• W2014019086 crossrefType "journal-article" @default.
• W2014019086 hasAuthorship W2014019086A5013561411 @default.
• W2014019086 hasAuthorship W2014019086A5051514780 @default.
• W2014019086 hasAuthorship W2014019086A5076286709 @default.
• W2014019086 hasConcept C104317684 @default.
• W2014019086 hasConcept C104451858 @default.
• W2014019086 hasConcept C143425029 @default.
• W2014019086 hasConcept C153911025 @default.
• W2014019086 hasConcept C178790620 @default.
• W2014019086 hasConcept C185592680 @default.
• W2014019086 hasConcept C190283241 @default.
• W2014019086 hasConcept C2776639595 @default.
• W2014019086 hasConcept C2776907736 @default.
• W2014019086 hasConcept C2778959862 @default.
• W2014019086 hasConcept C2779102032 @default.
• W2014019086 hasConcept C29730261 @default.
• W2014019086 hasConcept C29906990 @default.
• W2014019086 hasConcept C501734568 @default.
• W2014019086 hasConcept C552990157 @default.
• W2014019086 hasConcept C55493867 @default.
• W2014019086 hasConcept C86803240 @default.
• W2014019086 hasConceptScore W2014019086C104317684 @default.
• W2014019086 hasConceptScore W2014019086C104451858 @default.
• W2014019086 hasConceptScore W2014019086C143425029 @default.
• W2014019086 hasConceptScore W2014019086C153911025 @default.
• W2014019086 hasConceptScore W2014019086C178790620 @default.
• W2014019086 hasConceptScore W2014019086C185592680 @default.
• W2014019086 hasConceptScore W2014019086C190283241 @default.
• W2014019086 hasConceptScore W2014019086C2776639595 @default.
• W2014019086 hasConceptScore W2014019086C2776907736 @default.
• W2014019086 hasConceptScore W2014019086C2778959862 @default.
• W2014019086 hasConceptScore W2014019086C2779102032 @default.
• W2014019086 hasConceptScore W2014019086C29730261 @default.
• W2014019086 hasConceptScore W2014019086C29906990 @default.
• W2014019086 hasConceptScore W2014019086C501734568 @default.
• W2014019086 hasConceptScore W2014019086C552990157 @default.
• W2014019086 hasConceptScore W2014019086C55493867 @default.
• W2014019086 hasConceptScore W2014019086C86803240 @default.
• W2014019086 hasIssue "1-2" @default.
• W2014019086 hasLocation W20140190861 @default.
• W2014019086 hasLocation W20140190862 @default.
• W2014019086 hasOpenAccess W2014019086 @default.
• W2014019086 hasPrimaryLocation W20140190861 @default.
• W2014019086 hasRelatedWork W1586066921 @default.
• W2014019086 hasRelatedWork W1973201582 @default.
• W2014019086 hasRelatedWork W1984001609 @default.
• W2014019086 hasRelatedWork W1984825104 @default.
• W2014019086 hasRelatedWork W2014019086 @default.
• W2014019086 hasRelatedWork W2045778538 @default.
• W2014019086 hasRelatedWork W2075429531 @default.
• W2014019086 hasRelatedWork W3125987111 @default.
• W2014019086 hasRelatedWork W3200977287 @default.
• W2014019086 hasRelatedWork W1438900922 @default.
• W2014019086 hasVolume "492" @default.
• W2014019086 isParatext "false" @default.
• W2014019086 isRetracted "false" @default.

• next