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- W2014033612 abstract "Recent work of Folin and Lyman1points to the conclusion that gout is caused by an accumulation of uric acid in the blood with a subsequent deposition of this in an insoluble form in the various tissues of the body, particularly in the joints and synovial membranes. The retention and consequent accumulation is due to a deficient and restricted power of the kidneys. By means of the new colorimetric method of Folin and Denis2these investigators have analyzed the blood from a large number of patients suffering from gout and have found the uric acid content higher than in normal individuals; in these patients the blood was frequently found to have reached the saturation point for this compound, namely, 4 mg. in 100 c.c. of blood. Atophan (2-phenylquinolin-4-carbonic acid) caused a decrease in the amount of uric acid in the blood and a corresponding increase in" @default.
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- W2014033612 date "1914-03-01" @default.
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- W2014033612 title "THE INFLUENCE OF LITHIUM AND ATOPHAN ON THE URIC ACID EXCRETION OF A GOUTY PATIENT" @default.
- W2014033612 doi "https://doi.org/10.1001/archinte.1914.00070090133008" @default.
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