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• W2014071256 abstract "Abstract We report the synthesis of several substituted 3,4-dihydro-2H-1,3-benzoxazines by simple ring closure of 2-hydroxybenzylamines with paraformaldehyde. The facile synthesis of the benzylamine precursors from commercially available salicylaldehyde derivatives affords a powerful general synthetic way to prepare a variety of substituted benzoxazines, avoiding the formation of undesirable oligomeric species, thus leading to a simple workup and improving the yield and purity of the final product. This straightforward method allows synthesis of hydroxy-substituted and deuterium-labeled 1,3-benzoxazines that are not attainable using other synthetic ways." @default.
• W2014071256 created "2016-06-24" @default.
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• W2014071256 creator A5053910869 @default.
• W2014071256 date "2008-06-27" @default.
• W2014071256 modified "2023-09-27" @default.
• W2014071256 title "Synthesis of 3,4-Dihydro-2H-1,3-benzoxazines by Condensation of 2-Hydroxyaldehydes and Primary Amines: Application to the Synthesis of Hydroxy-Substituted and Deuterium-Labeled Compounds" @default.
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• W2014071256 doi "https://doi.org/10.1080/00397910802138629" @default.
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