Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014073110> ?p ?o ?g. }
- W2014073110 endingPage "15177" @default.
- W2014073110 startingPage "15172" @default.
- W2014073110 abstract "When spores of the anaerobic bacterium Clostridium novyi-NT are systemically injected into animals, they germinate exclusively within the hypoxic regions of cancers. The germinated bacteria destroy adjacent tumor cells but spare a rim of well oxygenated tumor cells that subsequently expand. Surprisingly, we found that ≈30% of mice treated with such spores were cured of their cancers despite the viable tumor rim initially remaining after spore germination. The mechanism underlying this effect was shown to be immune-mediated, because cured animals rejected a subsequent challenge of the same tumor. Similar effects were observed in rabbits with intrahepatic tumors. It was particularly notable that the induced immune response, when combined with the bacteriolytic effects of C. novyi-NT , could eradicate large established tumors." @default.
- W2014073110 created "2016-06-24" @default.
- W2014073110 creator A5013214842 @default.
- W2014073110 creator A5031310463 @default.
- W2014073110 creator A5031967115 @default.
- W2014073110 creator A5041082382 @default.
- W2014073110 creator A5043028963 @default.
- W2014073110 creator A5046392457 @default.
- W2014073110 creator A5049568817 @default.
- W2014073110 creator A5050789569 @default.
- W2014073110 creator A5053487762 @default.
- W2014073110 creator A5059462255 @default.
- W2014073110 creator A5065695204 @default.
- W2014073110 creator A5069022903 @default.
- W2014073110 creator A5069558252 @default.
- W2014073110 creator A5072858943 @default.
- W2014073110 creator A5082348299 @default.
- W2014073110 creator A5090480629 @default.
- W2014073110 date "2004-10-07" @default.
- W2014073110 modified "2023-10-11" @default.
- W2014073110 title "Bacteriolytic therapy can generate a potent immune response against experimental tumors" @default.
- W2014073110 cites W1595241211 @default.
- W2014073110 cites W1890466892 @default.
- W2014073110 cites W1966278918 @default.
- W2014073110 cites W1967425011 @default.
- W2014073110 cites W1975437869 @default.
- W2014073110 cites W1976763521 @default.
- W2014073110 cites W1990668606 @default.
- W2014073110 cites W1999834081 @default.
- W2014073110 cites W2000347848 @default.
- W2014073110 cites W2006194805 @default.
- W2014073110 cites W2017387425 @default.
- W2014073110 cites W2040977790 @default.
- W2014073110 cites W2046796641 @default.
- W2014073110 cites W2046800806 @default.
- W2014073110 cites W2046894146 @default.
- W2014073110 cites W2056879548 @default.
- W2014073110 cites W2069200323 @default.
- W2014073110 cites W2081442714 @default.
- W2014073110 cites W2082792779 @default.
- W2014073110 cites W2083040816 @default.
- W2014073110 cites W2094381598 @default.
- W2014073110 cites W2096016418 @default.
- W2014073110 cites W2102578857 @default.
- W2014073110 cites W2116593943 @default.
- W2014073110 cites W2119681037 @default.
- W2014073110 cites W2130614990 @default.
- W2014073110 cites W2131774025 @default.
- W2014073110 cites W2150048971 @default.
- W2014073110 cites W2154787543 @default.
- W2014073110 cites W2161456280 @default.
- W2014073110 cites W2165871546 @default.
- W2014073110 cites W2171162668 @default.
- W2014073110 cites W2285832969 @default.
- W2014073110 cites W4235179913 @default.
- W2014073110 doi "https://doi.org/10.1073/pnas.0406242101" @default.
- W2014073110 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/523456" @default.
- W2014073110 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15471990" @default.
- W2014073110 hasPublicationYear "2004" @default.
- W2014073110 type Work @default.
- W2014073110 sameAs 2014073110 @default.
- W2014073110 citedByCount "238" @default.
- W2014073110 countsByYear W20140731102012 @default.
- W2014073110 countsByYear W20140731102013 @default.
- W2014073110 countsByYear W20140731102014 @default.
- W2014073110 countsByYear W20140731102015 @default.
- W2014073110 countsByYear W20140731102016 @default.
- W2014073110 countsByYear W20140731102017 @default.
- W2014073110 countsByYear W20140731102018 @default.
- W2014073110 countsByYear W20140731102019 @default.
- W2014073110 countsByYear W20140731102020 @default.
- W2014073110 countsByYear W20140731102021 @default.
- W2014073110 countsByYear W20140731102022 @default.
- W2014073110 countsByYear W20140731102023 @default.
- W2014073110 crossrefType "journal-article" @default.
- W2014073110 hasAuthorship W2014073110A5013214842 @default.
- W2014073110 hasAuthorship W2014073110A5031310463 @default.
- W2014073110 hasAuthorship W2014073110A5031967115 @default.
- W2014073110 hasAuthorship W2014073110A5041082382 @default.
- W2014073110 hasAuthorship W2014073110A5043028963 @default.
- W2014073110 hasAuthorship W2014073110A5046392457 @default.
- W2014073110 hasAuthorship W2014073110A5049568817 @default.
- W2014073110 hasAuthorship W2014073110A5050789569 @default.
- W2014073110 hasAuthorship W2014073110A5053487762 @default.
- W2014073110 hasAuthorship W2014073110A5059462255 @default.
- W2014073110 hasAuthorship W2014073110A5065695204 @default.
- W2014073110 hasAuthorship W2014073110A5069022903 @default.
- W2014073110 hasAuthorship W2014073110A5069558252 @default.
- W2014073110 hasAuthorship W2014073110A5072858943 @default.
- W2014073110 hasAuthorship W2014073110A5082348299 @default.
- W2014073110 hasAuthorship W2014073110A5090480629 @default.
- W2014073110 hasBestOaLocation W20140731102 @default.
- W2014073110 hasConcept C100701293 @default.
- W2014073110 hasConcept C174618031 @default.
- W2014073110 hasConcept C203014093 @default.
- W2014073110 hasConcept C2781092032 @default.
- W2014073110 hasConcept C502942594 @default.
- W2014073110 hasConcept C523546767 @default.