Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014077370> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2014077370 endingPage "1077" @default.
- W2014077370 startingPage "1072" @default.
- W2014077370 abstract "Object. The authors studied the effect of gender and hormonal status on survival in nude rats implanted with human glioblastoma multiforme (GBM) cell lines. Methods. Nude rats received intracerebral implants of either wild-type U87MG cells or U87MG cells transfected with the gene for endothelin-1 (U87/ET-1). In the initial study, survival was compared in males and females for each of the two cell lines. The six second-phase study groups were composed of: 1) males; 2) females; 3) ovariectomized females; 4) sham ovariectomized females; 5) ovariectomized rats given 10 µg/day estradiol benzoate for 21 days; and 6) ovariectomized rats given 20 mg/kg/day progesterone for 21 days. All rats in the second phase were implanted with U87/ET-1 cells. Animals were killed when they exhibited initial signs of neurological deterioration. Female nude rats survived longer than male rats implanted with either U87 or U87/ET-1 cells. In the second phase, ovariectomized, male, and progesterone-treated rats died at approximately 19 days, whereas the female, sham-treated, and estrogen-treated animals died 23 to 25 days after tumor cell implantation. Conclusions. The authors demonstrate that female nude rats implanted with human GBM cells have a survival advantage over male rats and that estrogen provides the advantage." @default.
- W2014077370 created "2016-06-24" @default.
- W2014077370 creator A5000002403 @default.
- W2014077370 creator A5011944665 @default.
- W2014077370 creator A5074020047 @default.
- W2014077370 creator A5079876094 @default.
- W2014077370 creator A5088500348 @default.
- W2014077370 date "1999-06-01" @default.
- W2014077370 modified "2023-10-06" @default.
- W2014077370 title "Hormonal effects on glioblastoma multiforme in the nude rat model" @default.
- W2014077370 cites W191454705 @default.
- W2014077370 cites W1963582149 @default.
- W2014077370 cites W1974496138 @default.
- W2014077370 cites W1983964043 @default.
- W2014077370 cites W1985086182 @default.
- W2014077370 cites W1987277133 @default.
- W2014077370 cites W2003178083 @default.
- W2014077370 cites W2033200952 @default.
- W2014077370 cites W2044110633 @default.
- W2014077370 cites W2051541302 @default.
- W2014077370 cites W2051996964 @default.
- W2014077370 cites W2055601300 @default.
- W2014077370 cites W2064004890 @default.
- W2014077370 cites W2067900029 @default.
- W2014077370 cites W2068747346 @default.
- W2014077370 cites W2082057360 @default.
- W2014077370 cites W209702948 @default.
- W2014077370 cites W2102314385 @default.
- W2014077370 cites W2105850998 @default.
- W2014077370 cites W2111511587 @default.
- W2014077370 cites W2132184872 @default.
- W2014077370 cites W2154798785 @default.
- W2014077370 cites W2171150197 @default.
- W2014077370 cites W2330248224 @default.
- W2014077370 cites W2402501619 @default.
- W2014077370 doi "https://doi.org/10.3171/jns.1999.90.6.1072" @default.
- W2014077370 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10350254" @default.
- W2014077370 hasPublicationYear "1999" @default.
- W2014077370 type Work @default.
- W2014077370 sameAs 2014077370 @default.
- W2014077370 citedByCount "53" @default.
- W2014077370 countsByYear W20140773702012 @default.
- W2014077370 countsByYear W20140773702013 @default.
- W2014077370 countsByYear W20140773702014 @default.
- W2014077370 countsByYear W20140773702015 @default.
- W2014077370 countsByYear W20140773702017 @default.
- W2014077370 countsByYear W20140773702018 @default.
- W2014077370 countsByYear W20140773702019 @default.
- W2014077370 countsByYear W20140773702020 @default.
- W2014077370 countsByYear W20140773702021 @default.
- W2014077370 countsByYear W20140773702023 @default.
- W2014077370 crossrefType "journal-article" @default.
- W2014077370 hasAuthorship W2014077370A5000002403 @default.
- W2014077370 hasAuthorship W2014077370A5011944665 @default.
- W2014077370 hasAuthorship W2014077370A5074020047 @default.
- W2014077370 hasAuthorship W2014077370A5079876094 @default.
- W2014077370 hasAuthorship W2014077370A5088500348 @default.
- W2014077370 hasConcept C121608353 @default.
- W2014077370 hasConcept C126322002 @default.
- W2014077370 hasConcept C134018914 @default.
- W2014077370 hasConcept C2777164284 @default.
- W2014077370 hasConcept C2778506572 @default.
- W2014077370 hasConcept C2780278673 @default.
- W2014077370 hasConcept C71315377 @default.
- W2014077370 hasConcept C71924100 @default.
- W2014077370 hasConcept C8264082 @default.
- W2014077370 hasConceptScore W2014077370C121608353 @default.
- W2014077370 hasConceptScore W2014077370C126322002 @default.
- W2014077370 hasConceptScore W2014077370C134018914 @default.
- W2014077370 hasConceptScore W2014077370C2777164284 @default.
- W2014077370 hasConceptScore W2014077370C2778506572 @default.
- W2014077370 hasConceptScore W2014077370C2780278673 @default.
- W2014077370 hasConceptScore W2014077370C71315377 @default.
- W2014077370 hasConceptScore W2014077370C71924100 @default.
- W2014077370 hasConceptScore W2014077370C8264082 @default.
- W2014077370 hasIssue "6" @default.
- W2014077370 hasLocation W20140773701 @default.
- W2014077370 hasLocation W20140773702 @default.
- W2014077370 hasOpenAccess W2014077370 @default.
- W2014077370 hasPrimaryLocation W20140773701 @default.
- W2014077370 hasRelatedWork W1981503997 @default.
- W2014077370 hasRelatedWork W2002384464 @default.
- W2014077370 hasRelatedWork W2028698544 @default.
- W2014077370 hasRelatedWork W2071688816 @default.
- W2014077370 hasRelatedWork W2086583026 @default.
- W2014077370 hasRelatedWork W2087163313 @default.
- W2014077370 hasRelatedWork W2108578925 @default.
- W2014077370 hasRelatedWork W2113752661 @default.
- W2014077370 hasRelatedWork W2156499301 @default.
- W2014077370 hasRelatedWork W2167902350 @default.
- W2014077370 hasVolume "90" @default.
- W2014077370 isParatext "false" @default.
- W2014077370 isRetracted "false" @default.
- W2014077370 magId "2014077370" @default.
- W2014077370 workType "article" @default.