FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014093513> ?p ?o ?g. }

• W2014093513 endingPage "1822" @default.
• W2014093513 startingPage "1811" @default.
• W2014093513 abstract "Heterochromatinization at the silent mating-type loci HMR and HML in Saccharomyces cerevisiae is achieved by targeting the Sir complex to these regions via a set of anchor proteins that bind to the silencers. Here, we have identified a novel heterochromatin-targeting factor for HML, the protein Sum1, a repressor of meiotic genes during vegetative growth. Sum1 bound both in vitro and in vivo to HML via a functional element within the HML-E silencer, and sum1Delta caused HML derepression. Significantly, Sum1 was also required for origin activity of HML-E, demonstrating a role of Sum1 in replication initiation. In a genome-wide search for Sum1-regulated origins, we identified a set of autonomous replicative sequences (ARS elements) that bound both the origin recognition complex and Sum1. Full initiation activity of these origins required Sum1, and their origin activity was decreased upon removal of the Sum1-binding site. Thus, Sum1 constitutes a novel global regulator of replication initiation in yeast." @default.
• W2014093513 created "2016-06-24" @default.
• W2014093513 creator A5009628707 @default.
• W2014093513 creator A5060587616 @default.
• W2014093513 creator A5064188957 @default.
• W2014093513 creator A5068718826 @default.
• W2014093513 creator A5071463749 @default.
• W2014093513 date "2005-08-01" @default.
• W2014093513 modified "2023-10-16" @default.
• W2014093513 title "Control of replication initiation and heterochromatin formation in <i>Saccharomyces cerevisiae</i> by a regulator of meiotic gene expression" @default.
• W2014093513 cites W1544617408 @default.
• W2014093513 cites W1794952483 @default.
• W2014093513 cites W1806205354 @default.
• W2014093513 cites W1897872332 @default.
• W2014093513 cites W1901598339 @default.
• W2014093513 cites W1975939844 @default.
• W2014093513 cites W1982453928 @default.
• W2014093513 cites W1991107478 @default.
• W2014093513 cites W1993623149 @default.
• W2014093513 cites W1993751571 @default.
• W2014093513 cites W1995111407 @default.
• W2014093513 cites W2000625991 @default.
• W2014093513 cites W2002907731 @default.
• W2014093513 cites W2003798106 @default.
• W2014093513 cites W2005199456 @default.
• W2014093513 cites W2008486131 @default.
• W2014093513 cites W2010256888 @default.
• W2014093513 cites W2026290399 @default.
• W2014093513 cites W2042542044 @default.
• W2014093513 cites W2044279758 @default.
• W2014093513 cites W2047371315 @default.
• W2014093513 cites W2057587708 @default.
• W2014093513 cites W2061449183 @default.
• W2014093513 cites W2062662915 @default.
• W2014093513 cites W2073271955 @default.
• W2014093513 cites W2086143596 @default.
• W2014093513 cites W2088493129 @default.
• W2014093513 cites W2094051937 @default.
• W2014093513 cites W2097948853 @default.
• W2014093513 cites W2102822826 @default.
• W2014093513 cites W2105487944 @default.
• W2014093513 cites W2106130068 @default.
• W2014093513 cites W2108717767 @default.
• W2014093513 cites W2113391242 @default.
• W2014093513 cites W2117716312 @default.
• W2014093513 cites W2120752254 @default.
• W2014093513 cites W2121228312 @default.
• W2014093513 cites W2121368256 @default.
• W2014093513 cites W2125118113 @default.
• W2014093513 cites W2125717020 @default.
• W2014093513 cites W2126602684 @default.
• W2014093513 cites W2127759364 @default.
• W2014093513 cites W2134486677 @default.
• W2014093513 cites W2134790568 @default.
• W2014093513 cites W2135342180 @default.
• W2014093513 cites W2142294062 @default.
• W2014093513 cites W2151316017 @default.
• W2014093513 cites W2155802675 @default.
• W2014093513 cites W2159385826 @default.
• W2014093513 cites W2159723512 @default.
• W2014093513 cites W2165158667 @default.
• W2014093513 cites W2170326957 @default.
• W2014093513 cites W2171867148 @default.
• W2014093513 cites W2178238598 @default.
• W2014093513 cites W2182220639 @default.
• W2014093513 cites W2223570412 @default.
• W2014093513 cites W2270552653 @default.
• W2014093513 cites W2331188160 @default.
• W2014093513 doi "https://doi.org/10.1101/gad.334805" @default.
• W2014093513 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1182343" @default.
• W2014093513 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16077008" @default.
• W2014093513 hasPublicationYear "2005" @default.
• W2014093513 type Work @default.
• W2014093513 sameAs 2014093513 @default.
• W2014093513 citedByCount "52" @default.
• W2014093513 countsByYear W20140935132012 @default.
• W2014093513 countsByYear W20140935132013 @default.
• W2014093513 countsByYear W20140935132014 @default.
• W2014093513 countsByYear W20140935132016 @default.
• W2014093513 countsByYear W20140935132019 @default.
• W2014093513 countsByYear W20140935132021 @default.
• W2014093513 countsByYear W20140935132022 @default.
• W2014093513 countsByYear W20140935132023 @default.
• W2014093513 crossrefType "journal-article" @default.
• W2014093513 hasAuthorship W2014093513A5009628707 @default.
• W2014093513 hasAuthorship W2014093513A5060587616 @default.
• W2014093513 hasAuthorship W2014093513A5064188957 @default.
• W2014093513 hasAuthorship W2014093513A5068718826 @default.
• W2014093513 hasAuthorship W2014093513A5071463749 @default.
• W2014093513 hasBestOaLocation W20140935131 @default.
• W2014093513 hasConcept C103435993 @default.
• W2014093513 hasConcept C104317684 @default.
• W2014093513 hasConcept C150194340 @default.
• W2014093513 hasConcept C151158763 @default.
• W2014093513 hasConcept C158448853 @default.
• W2014093513 hasConcept C186310378 @default.
• W2014093513 hasConcept C2777576037 @default.
• W2014093513 hasConcept C54266558 @default.

• next