FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014095762> ?p ?o ?g. }

• W2014095762 endingPage "533" @default.
• W2014095762 startingPage "529" @default.
• W2014095762 abstract "Anti-phospholipid antibodies (APA) may involve heart and valvular heart disease seems to be the most common clinical manifestation.To study the prevalence and characteristics of valvular heart disease in a large patient population with anti-phospholipid syndrome (APS) and also to analyze the clinical and immunological profile of patients with valvular involvement compared with those without involvement. Patients and methods. Retrospective analysis of 113 patients diagnosed of APS. Eighty-one percent were females and the mean age was 39 years (SD:14). Sixty-two percent of patients were diagnosed of primary APS (70 patients) and the remaining 38% (43 patients) corresponded to patients with APS associated with systemic lupus erythematosus (SLE). The median follow-up of patients was 55 months (range: 7-144 months). The cardiologic assessment was performed by means of transthoracic echocardiogram. The study of anti-lupus anticoagulant (AL) was performed by means of coagulometric assays and measurement of anticardiolipin antibodies (aCL), anti-beta2 glycoprotein I (abeta2-PGI) and anti-prothrombin (aPT) by ELISA.The prevalence of valvular heart disease was 19%. The mitral valve was mostly involved (91%) and the most common structural abnormality corresponded to mitral insufficiency. Valvular replacement was required in 24% of patients. In the subgroup of patients with valvular heart disease, a significantly higher prevalence was observed in the following parameters: total thrombosis (71% versus 49%; p = 0.05), arterial thrombosis (57% versus 23%; p = 0.002), stroke (38% versus 13%; p = 0.01), trombocitopenia (71% versus 45%; p = 0.02), hemolytic anemia (29% versus 9%; p = 0.02), and livedo reticularis (48% versus 3%; p < 0.0001). As for immunological differences, only a higher prevalence of LA was found (81% versus 59%; p= 0.04) and abeta2-GPI (IgG isotype) (43% versus 22%; p = 0.05) in patients with valvular heart disease.Valvular heart disease is more frequent in pa-tients with APS and mitral insufficiency is the most common lesion. In a patient with the diagnosis of APS, an echocar-digram should be obtained in his/her initial assessment and regular controls should be obtained in the follow-up." @default.
• W2014095762 created "2016-06-24" @default.
• W2014095762 creator A5011120094 @default.
• W2014095762 creator A5012260309 @default.
• W2014095762 creator A5019625487 @default.
• W2014095762 creator A5020613139 @default.
• W2014095762 creator A5067151653 @default.
• W2014095762 creator A5086624081 @default.
• W2014095762 date "2002-01-01" @default.
• W2014095762 modified "2023-10-01" @default.
• W2014095762 title "Cardiopatía valvular en pacientes con síndrome antifosfolipídico" @default.
• W2014095762 cites W188384924 @default.
• W2014095762 cites W1982029136 @default.
• W2014095762 cites W1992311484 @default.
• W2014095762 cites W1994284943 @default.
• W2014095762 cites W1998185194 @default.
• W2014095762 cites W2025911287 @default.
• W2014095762 cites W2032143325 @default.
• W2014095762 cites W2040428956 @default.
• W2014095762 cites W2044341259 @default.
• W2014095762 cites W2049681766 @default.
• W2014095762 cites W2052476486 @default.
• W2014095762 cites W2063571654 @default.
• W2014095762 cites W2087565417 @default.
• W2014095762 cites W2093920275 @default.
• W2014095762 cites W2103103052 @default.
• W2014095762 cites W2108708736 @default.
• W2014095762 cites W2120618749 @default.
• W2014095762 cites W2132099411 @default.
• W2014095762 cites W2138858884 @default.
• W2014095762 cites W2154607829 @default.
• W2014095762 cites W2165940166 @default.
• W2014095762 cites W2417920681 @default.
• W2014095762 doi "https://doi.org/10.1016/s0014-2565(02)71136-3" @default.
• W2014095762 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12361550" @default.
• W2014095762 hasPublicationYear "2002" @default.
• W2014095762 type Work @default.
• W2014095762 sameAs 2014095762 @default.
• W2014095762 citedByCount "10" @default.
• W2014095762 countsByYear W20140957622012 @default.
• W2014095762 countsByYear W20140957622020 @default.
• W2014095762 countsByYear W20140957622021 @default.
• W2014095762 countsByYear W20140957622022 @default.
• W2014095762 crossrefType "journal-article" @default.
• W2014095762 hasAuthorship W2014095762A5011120094 @default.
• W2014095762 hasAuthorship W2014095762A5012260309 @default.
• W2014095762 hasAuthorship W2014095762A5019625487 @default.
• W2014095762 hasAuthorship W2014095762A5020613139 @default.
• W2014095762 hasAuthorship W2014095762A5067151653 @default.
• W2014095762 hasAuthorship W2014095762A5086624081 @default.
• W2014095762 hasConcept C126322002 @default.
• W2014095762 hasConcept C127413603 @default.
• W2014095762 hasConcept C164705383 @default.
• W2014095762 hasConcept C2776874634 @default.
• W2014095762 hasConcept C2779736815 @default.
• W2014095762 hasConcept C2780022809 @default.
• W2014095762 hasConcept C2780645631 @default.
• W2014095762 hasConcept C2780868729 @default.
• W2014095762 hasConcept C2908647359 @default.
• W2014095762 hasConcept C71924100 @default.
• W2014095762 hasConcept C78519656 @default.
• W2014095762 hasConcept C99454951 @default.
• W2014095762 hasConceptScore W2014095762C126322002 @default.
• W2014095762 hasConceptScore W2014095762C127413603 @default.
• W2014095762 hasConceptScore W2014095762C164705383 @default.
• W2014095762 hasConceptScore W2014095762C2776874634 @default.
• W2014095762 hasConceptScore W2014095762C2779736815 @default.
• W2014095762 hasConceptScore W2014095762C2780022809 @default.
• W2014095762 hasConceptScore W2014095762C2780645631 @default.
• W2014095762 hasConceptScore W2014095762C2780868729 @default.
• W2014095762 hasConceptScore W2014095762C2908647359 @default.
• W2014095762 hasConceptScore W2014095762C71924100 @default.
• W2014095762 hasConceptScore W2014095762C78519656 @default.
• W2014095762 hasConceptScore W2014095762C99454951 @default.
• W2014095762 hasIssue "10" @default.
• W2014095762 hasLocation W20140957621 @default.
• W2014095762 hasLocation W20140957622 @default.
• W2014095762 hasOpenAccess W2014095762 @default.
• W2014095762 hasPrimaryLocation W20140957621 @default.
• W2014095762 hasRelatedWork W2041255087 @default.
• W2014095762 hasRelatedWork W2065238301 @default.
• W2014095762 hasRelatedWork W2260434562 @default.
• W2014095762 hasRelatedWork W2315600383 @default.
• W2014095762 hasRelatedWork W2416908680 @default.
• W2014095762 hasRelatedWork W2785256360 @default.
• W2014095762 hasRelatedWork W2807649910 @default.
• W2014095762 hasRelatedWork W3024308411 @default.
• W2014095762 hasRelatedWork W3092459053 @default.
• W2014095762 hasRelatedWork W361878593 @default.
• W2014095762 hasVolume "202" @default.
• W2014095762 isParatext "false" @default.
• W2014095762 isRetracted "false" @default.
• W2014095762 magId "2014095762" @default.
• W2014095762 workType "article" @default.