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- W2014106518 abstract "Abstract — Accumulation of bone micro-damage is suspected to lead to severe impairment of mechanical properties with an increase in skeletal fragility and fracture risk. The objective of the study was to evaluate the potential of Nonlinear Resonant Ultrasound Spectroscopy (NRUS) for measuring micro-damage accumulation in cortical bone using four-point bending cycling fatigue. Sixteen human cortical bone specimens were machined as parallelepiped beams. Damage progression was controlled by measuring the linear elastic beam theory modulus ( E LEBT ), known to reflect microdamage accumulation. Before and between each damage step, the nonlinear ultrasonic elastic coefficient was measured by NRUS. At the end of each cycling fatigue, a subset of bone samples was measured by µCT at the European Synchrotron Radiation Facility. Results showing a progressive increase of nonlinear ultrasonic elastic coefficient along fatigue cycling suggest that NRUS measurements are sensitive to micro-damage accumulation. The results mentioned above were validated using synchrotron radiation µCT. The variation of elastic nonlinearity was found to be significantly correlated to the variation of number density of small microcracks which almost doubled in damaged regions. Keywords-component; nonlinear; NRUS; microcracks; bone; fatigue" @default.
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- W2014106518 date "2011-10-01" @default.
- W2014106518 modified "2023-10-05" @default.
- W2014106518 title "Nonlinear ultrasound monitoring of fatigue microdamage accumulation in cortical bone" @default.
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- W2014106518 doi "https://doi.org/10.1109/ultsym.2011.0251" @default.
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