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• W2014106668 abstract "Abstract Background. Our aim was to investigate the prevalence and the clinical role of salivary hypofunction in patients with globus sensation. Methods. We conducted a prospective observational study in 340 patients with globus pharyngeus. A standard questionnaire and 99m Tc‐pertechnate salivary scintigraphy were used to evaluate salivary hypofunction, with a full examination from the nasal cavity to the larynx ( N = 303). We also investigated the effect of xerostomia management on globus symptoms ( N = 252). Results. The symptom scores for xerostomia were higher in patients with severe globus ( p < .05). Objective salivary hypofunction was noted in 57.4% of the patients, based on the reference values from control groups. Globus symptoms were more severe in the subgroup with salivary hypofunction ( p = .0447). Conservative management of xerostomia significantly reduced the severity of globus at 1 and 3 months ( p = .0002) regardless of salivary function. Conclusions. Salivary hypofunction seems to be an aggravating factor in globus pharyngeus, but not a direct cause. Conservative management of xerostomia improves globus symptoms. © 2009 Wiley Periodicals, Inc. Head Neck, 2010" @default.
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• W2014106668 date "2009-07-01" @default.
• W2014106668 modified "2023-10-18" @default.
• W2014106668 title "Role of salivary function in patients with globus pharyngeus" @default.
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• W2014106668 doi "https://doi.org/10.1002/hed.21176" @default.
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