Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014115910> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2014115910 endingPage "2853" @default.
- W2014115910 startingPage "2844" @default.
- W2014115910 abstract "13C-NMR relaxation experiments (T(1), T(2), T(1)(rho), and NOE) were performed on selectively enriched residues in two peptides, one hydrophobic staple alpha-helix-forming peptide GFSKAELAKARAAKRGGY and one beta-hairpin-forming peptide RGITVNGKTYGR, in water and in water/trifluoroethanol (TFE). Exchange contributions, R(ex), to spin-spin relaxation rates for (13)C(alpha) and (13)C(beta) groups were derived and were ascribed to be mainly due to peptide folding-unfolding. To evaluate the exchange time, tau(ex), from R(ex), the chemical shift difference between folded and unfolded states, Deltadelta, and the populations of these states, p(i), were determined from the temperature dependence of (13)C chemical shifts. For both peptides, values for tau(ex) fell in the 1 micros to 10 micros range. Under conditions where the peptides are most folded (water/TFE, 5 degrees C), tau(ex) values for all residues in each respective peptide were essentially the same, supporting the presence of a global folding-unfolding exchange process. Rounded-up average tau(ex) values were 4 micros for the helix peptide and 9 micros for the hairpin peptide. This 2-3-fold difference in exchange times between helix and hairpin peptides is consistent with that observed for folding-unfolding of other small peptides." @default.
- W2014115910 created "2016-06-24" @default.
- W2014115910 creator A5006035574 @default.
- W2014115910 creator A5012810451 @default.
- W2014115910 creator A5029096955 @default.
- W2014115910 creator A5036721454 @default.
- W2014115910 creator A5063427546 @default.
- W2014115910 creator A5065211265 @default.
- W2014115910 creator A5068327245 @default.
- W2014115910 creator A5080707475 @default.
- W2014115910 date "2001-02-01" @default.
- W2014115910 modified "2023-10-10" @default.
- W2014115910 title "Conformational Exchange on the Microsecond Time Scale in α-Helix and β-Hairpin Peptides Measured by <sup>13</sup>C NMR Transverse Relaxation" @default.
- W2014115910 cites W1207355684 @default.
- W2014115910 cites W167277884 @default.
- W2014115910 cites W1970414907 @default.
- W2014115910 cites W1971493452 @default.
- W2014115910 cites W1987528091 @default.
- W2014115910 cites W1991735545 @default.
- W2014115910 cites W1994681621 @default.
- W2014115910 cites W2090208503 @default.
- W2014115910 cites W2165849976 @default.
- W2014115910 doi "https://doi.org/10.1021/bi001293b" @default.
- W2014115910 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11258895" @default.
- W2014115910 hasPublicationYear "2001" @default.
- W2014115910 type Work @default.
- W2014115910 sameAs 2014115910 @default.
- W2014115910 citedByCount "17" @default.
- W2014115910 countsByYear W20141159102014 @default.
- W2014115910 crossrefType "journal-article" @default.
- W2014115910 hasAuthorship W2014115910A5006035574 @default.
- W2014115910 hasAuthorship W2014115910A5012810451 @default.
- W2014115910 hasAuthorship W2014115910A5029096955 @default.
- W2014115910 hasAuthorship W2014115910A5036721454 @default.
- W2014115910 hasAuthorship W2014115910A5063427546 @default.
- W2014115910 hasAuthorship W2014115910A5065211265 @default.
- W2014115910 hasAuthorship W2014115910A5068327245 @default.
- W2014115910 hasAuthorship W2014115910A5080707475 @default.
- W2014115910 hasConcept C111429119 @default.
- W2014115910 hasConcept C119599485 @default.
- W2014115910 hasConcept C121332964 @default.
- W2014115910 hasConcept C127413603 @default.
- W2014115910 hasConcept C1276947 @default.
- W2014115910 hasConcept C147789679 @default.
- W2014115910 hasConcept C15744967 @default.
- W2014115910 hasConcept C185592680 @default.
- W2014115910 hasConcept C18903297 @default.
- W2014115910 hasConcept C204328495 @default.
- W2014115910 hasConcept C2776029896 @default.
- W2014115910 hasConcept C2776545253 @default.
- W2014115910 hasConcept C2778530040 @default.
- W2014115910 hasConcept C2779281246 @default.
- W2014115910 hasConcept C2779965526 @default.
- W2014115910 hasConcept C34742353 @default.
- W2014115910 hasConcept C55493867 @default.
- W2014115910 hasConcept C77805123 @default.
- W2014115910 hasConcept C8010536 @default.
- W2014115910 hasConcept C86803240 @default.
- W2014115910 hasConceptScore W2014115910C111429119 @default.
- W2014115910 hasConceptScore W2014115910C119599485 @default.
- W2014115910 hasConceptScore W2014115910C121332964 @default.
- W2014115910 hasConceptScore W2014115910C127413603 @default.
- W2014115910 hasConceptScore W2014115910C1276947 @default.
- W2014115910 hasConceptScore W2014115910C147789679 @default.
- W2014115910 hasConceptScore W2014115910C15744967 @default.
- W2014115910 hasConceptScore W2014115910C185592680 @default.
- W2014115910 hasConceptScore W2014115910C18903297 @default.
- W2014115910 hasConceptScore W2014115910C204328495 @default.
- W2014115910 hasConceptScore W2014115910C2776029896 @default.
- W2014115910 hasConceptScore W2014115910C2776545253 @default.
- W2014115910 hasConceptScore W2014115910C2778530040 @default.
- W2014115910 hasConceptScore W2014115910C2779281246 @default.
- W2014115910 hasConceptScore W2014115910C2779965526 @default.
- W2014115910 hasConceptScore W2014115910C34742353 @default.
- W2014115910 hasConceptScore W2014115910C55493867 @default.
- W2014115910 hasConceptScore W2014115910C77805123 @default.
- W2014115910 hasConceptScore W2014115910C8010536 @default.
- W2014115910 hasConceptScore W2014115910C86803240 @default.
- W2014115910 hasIssue "9" @default.
- W2014115910 hasLocation W20141159101 @default.
- W2014115910 hasLocation W20141159102 @default.
- W2014115910 hasOpenAccess W2014115910 @default.
- W2014115910 hasPrimaryLocation W20141159101 @default.
- W2014115910 hasRelatedWork W2023600921 @default.
- W2014115910 hasRelatedWork W2055827177 @default.
- W2014115910 hasRelatedWork W2072666835 @default.
- W2014115910 hasRelatedWork W2113188411 @default.
- W2014115910 hasRelatedWork W2260493136 @default.
- W2014115910 hasRelatedWork W2382178265 @default.
- W2014115910 hasRelatedWork W2611220716 @default.
- W2014115910 hasRelatedWork W2939859775 @default.
- W2014115910 hasRelatedWork W2976965029 @default.
- W2014115910 hasRelatedWork W4210423528 @default.
- W2014115910 hasVolume "40" @default.
- W2014115910 isParatext "false" @default.
- W2014115910 isRetracted "false" @default.
- W2014115910 magId "2014115910" @default.
- W2014115910 workType "article" @default.