Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014118527> ?p ?o ?g. }
Showing items 1 to 66 of
66
with 100 items per page.
- W2014118527 endingPage "1546" @default.
- W2014118527 startingPage "1546" @default.
- W2014118527 abstract "The biosynthetic problem posed by the macrocycle of the natural porphyrins, chlorins, and corrins is outlined together with the approaches being used for its solution. Routes are developed as follows for rational synthesis of the labelled (aminomethyl)pyrromethanes (6) and (7), which are of importance for incorporation studies on haem, protoporphyrin-IX, and vitamin B12. An improved sequence affords porphobilinogen lactam methyl ester (16) labelled in the propionic ester residue. The 5-(chloromethyl)pyrrole (24) is synthesised carrying 14C-labels at the C-4 methylene and C-5 methylene groups. A similar synthesis yields the labelled isomeric (chloromethyl)pyrrole (52). These three building blocks are used for synthesis of the pyrromethane lactams (27) and (55) of proven homogeneity labelled specifically with carbon-14 in the side-chains and at the bridge methylene group. Hydrolysis of the lactams affords the labelled (aminomethyl)pyrromethanes (6) and (7)." @default.
- W2014118527 created "2016-06-24" @default.
- W2014118527 creator A5002507459 @default.
- W2014118527 creator A5035782410 @default.
- W2014118527 creator A5041900322 @default.
- W2014118527 creator A5046937488 @default.
- W2014118527 creator A5075537902 @default.
- W2014118527 date "1973-01-01" @default.
- W2014118527 modified "2023-09-23" @default.
- W2014118527 title "Biosynthesis of porphyrins and related macrocycles. Part I. Synthesis of 14C-labelled pyrromethanes" @default.
- W2014118527 doi "https://doi.org/10.1039/p19730001546" @default.
- W2014118527 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4796388" @default.
- W2014118527 hasPublicationYear "1973" @default.
- W2014118527 type Work @default.
- W2014118527 sameAs 2014118527 @default.
- W2014118527 citedByCount "18" @default.
- W2014118527 crossrefType "journal-article" @default.
- W2014118527 hasAuthorship W2014118527A5002507459 @default.
- W2014118527 hasAuthorship W2014118527A5035782410 @default.
- W2014118527 hasAuthorship W2014118527A5041900322 @default.
- W2014118527 hasAuthorship W2014118527A5046937488 @default.
- W2014118527 hasAuthorship W2014118527A5075537902 @default.
- W2014118527 hasConcept C178790620 @default.
- W2014118527 hasConcept C181199279 @default.
- W2014118527 hasConcept C185592680 @default.
- W2014118527 hasConcept C21951064 @default.
- W2014118527 hasConcept C2776682811 @default.
- W2014118527 hasConcept C2777454769 @default.
- W2014118527 hasConcept C2779400197 @default.
- W2014118527 hasConcept C2779671804 @default.
- W2014118527 hasConcept C2781323092 @default.
- W2014118527 hasConcept C2781338088 @default.
- W2014118527 hasConcept C71240020 @default.
- W2014118527 hasConcept C94412978 @default.
- W2014118527 hasConceptScore W2014118527C178790620 @default.
- W2014118527 hasConceptScore W2014118527C181199279 @default.
- W2014118527 hasConceptScore W2014118527C185592680 @default.
- W2014118527 hasConceptScore W2014118527C21951064 @default.
- W2014118527 hasConceptScore W2014118527C2776682811 @default.
- W2014118527 hasConceptScore W2014118527C2777454769 @default.
- W2014118527 hasConceptScore W2014118527C2779400197 @default.
- W2014118527 hasConceptScore W2014118527C2779671804 @default.
- W2014118527 hasConceptScore W2014118527C2781323092 @default.
- W2014118527 hasConceptScore W2014118527C2781338088 @default.
- W2014118527 hasConceptScore W2014118527C71240020 @default.
- W2014118527 hasConceptScore W2014118527C94412978 @default.
- W2014118527 hasLocation W20141185271 @default.
- W2014118527 hasLocation W20141185272 @default.
- W2014118527 hasOpenAccess W2014118527 @default.
- W2014118527 hasPrimaryLocation W20141185271 @default.
- W2014118527 hasRelatedWork W2014118527 @default.
- W2014118527 hasRelatedWork W2044542204 @default.
- W2014118527 hasRelatedWork W2073863100 @default.
- W2014118527 hasRelatedWork W2095581038 @default.
- W2014118527 hasRelatedWork W2175561168 @default.
- W2014118527 hasRelatedWork W2331077834 @default.
- W2014118527 hasRelatedWork W2338996536 @default.
- W2014118527 hasRelatedWork W2403182174 @default.
- W2014118527 hasRelatedWork W2950038481 @default.
- W2014118527 hasRelatedWork W2953374257 @default.
- W2014118527 isParatext "false" @default.
- W2014118527 isRetracted "false" @default.
- W2014118527 magId "2014118527" @default.
- W2014118527 workType "article" @default.