Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014128596> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2014128596 endingPage "176" @default.
- W2014128596 startingPage "171" @default.
- W2014128596 abstract "beta-Endorphin (5-80 microgram) or [D-Ala2,Met5]enkephalinamide (DALA) (5-40 microgram) was administered intracerebroventricularly to rats. With both opioid peptides, there was no direct relationship between log dose and mean number of wet-dog shakes (WDS) that occurred during the following 15 min. When the results were analyzed quantitatively, the dose of DALA that caused 50% of the rats to shake at least twice was 8.6 microgram (4.9-15 microgram). beta-Endorphin had such poor efficacy that an ED 50 could not be obtained. Morphine (1 and 5 mg/kg, s.c.) antagonized shaking caused by the optimal dose of DALA (20 microgram). Naloxone (0.1-10 mg/kg, s.c.) attenuated both DALA- and beta-endorphin-induced WDS in a dose-related manner. This latter result differentiates shaking associated with opioid peptides from that caused by thyrotropin releasing hormone (TRH), another endogenous stimulant of WDS in rats. There was no cross-tolerance between RX 336-M (7,8-dihydro-5',6'-dimethylcyclohex-5'-eno-1',2',8',14 codeinone), a novel shake inducing agent, and beta-endorphin. This finding again differentiates beta-endorphin-induced shaking from that caused by TRH and also from that associated with several exogenous stimulants of WDS." @default.
- W2014128596 created "2016-06-24" @default.
- W2014128596 creator A5005006087 @default.
- W2014128596 creator A5076799832 @default.
- W2014128596 date "1982-01-01" @default.
- W2014128596 modified "2023-10-09" @default.
- W2014128596 title "A quantitative analysis of the shaking behavior induced in rats by β-endorphin and [D-Ala2, Met5] enkephalinamide" @default.
- W2014128596 cites W1965166997 @default.
- W2014128596 cites W1966270902 @default.
- W2014128596 cites W1973412254 @default.
- W2014128596 cites W1989081971 @default.
- W2014128596 cites W2008071500 @default.
- W2014128596 cites W2020666670 @default.
- W2014128596 cites W2021550889 @default.
- W2014128596 cites W2028469457 @default.
- W2014128596 cites W2030288420 @default.
- W2014128596 cites W2035294814 @default.
- W2014128596 cites W2037856223 @default.
- W2014128596 cites W2050293341 @default.
- W2014128596 cites W2058783914 @default.
- W2014128596 cites W2067965765 @default.
- W2014128596 cites W2068236353 @default.
- W2014128596 cites W2077669642 @default.
- W2014128596 cites W2078515893 @default.
- W2014128596 cites W2082005308 @default.
- W2014128596 cites W2082498670 @default.
- W2014128596 cites W2083146991 @default.
- W2014128596 cites W2083313877 @default.
- W2014128596 cites W2088353732 @default.
- W2014128596 cites W2091689165 @default.
- W2014128596 doi "https://doi.org/10.1016/0024-3205(82)90649-x" @default.
- W2014128596 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6275233" @default.
- W2014128596 hasPublicationYear "1982" @default.
- W2014128596 type Work @default.
- W2014128596 sameAs 2014128596 @default.
- W2014128596 citedByCount "20" @default.
- W2014128596 crossrefType "journal-article" @default.
- W2014128596 hasAuthorship W2014128596A5005006087 @default.
- W2014128596 hasAuthorship W2014128596A5076799832 @default.
- W2014128596 hasConcept C126322002 @default.
- W2014128596 hasConcept C134018914 @default.
- W2014128596 hasConcept C170493617 @default.
- W2014128596 hasConcept C185592680 @default.
- W2014128596 hasConcept C202751555 @default.
- W2014128596 hasConcept C2776216936 @default.
- W2014128596 hasConcept C2777557602 @default.
- W2014128596 hasConcept C2778680817 @default.
- W2014128596 hasConcept C2778750930 @default.
- W2014128596 hasConcept C2780557958 @default.
- W2014128596 hasConcept C2781063702 @default.
- W2014128596 hasConcept C51296783 @default.
- W2014128596 hasConcept C55493867 @default.
- W2014128596 hasConcept C71315377 @default.
- W2014128596 hasConcept C71924100 @default.
- W2014128596 hasConcept C88016717 @default.
- W2014128596 hasConceptScore W2014128596C126322002 @default.
- W2014128596 hasConceptScore W2014128596C134018914 @default.
- W2014128596 hasConceptScore W2014128596C170493617 @default.
- W2014128596 hasConceptScore W2014128596C185592680 @default.
- W2014128596 hasConceptScore W2014128596C202751555 @default.
- W2014128596 hasConceptScore W2014128596C2776216936 @default.
- W2014128596 hasConceptScore W2014128596C2777557602 @default.
- W2014128596 hasConceptScore W2014128596C2778680817 @default.
- W2014128596 hasConceptScore W2014128596C2778750930 @default.
- W2014128596 hasConceptScore W2014128596C2780557958 @default.
- W2014128596 hasConceptScore W2014128596C2781063702 @default.
- W2014128596 hasConceptScore W2014128596C51296783 @default.
- W2014128596 hasConceptScore W2014128596C55493867 @default.
- W2014128596 hasConceptScore W2014128596C71315377 @default.
- W2014128596 hasConceptScore W2014128596C71924100 @default.
- W2014128596 hasConceptScore W2014128596C88016717 @default.
- W2014128596 hasIssue "2" @default.
- W2014128596 hasLocation W20141285961 @default.
- W2014128596 hasLocation W20141285962 @default.
- W2014128596 hasOpenAccess W2014128596 @default.
- W2014128596 hasPrimaryLocation W20141285961 @default.
- W2014128596 hasRelatedWork W1982340962 @default.
- W2014128596 hasRelatedWork W2032307762 @default.
- W2014128596 hasRelatedWork W2058070515 @default.
- W2014128596 hasRelatedWork W2082268521 @default.
- W2014128596 hasRelatedWork W2091241147 @default.
- W2014128596 hasRelatedWork W2133591619 @default.
- W2014128596 hasRelatedWork W2404703847 @default.
- W2014128596 hasRelatedWork W2407662096 @default.
- W2014128596 hasRelatedWork W2954437642 @default.
- W2014128596 hasRelatedWork W3037926329 @default.
- W2014128596 hasVolume "30" @default.
- W2014128596 isParatext "false" @default.
- W2014128596 isRetracted "false" @default.
- W2014128596 magId "2014128596" @default.
- W2014128596 workType "article" @default.