Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014139218> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W2014139218 endingPage "262" @default.
- W2014139218 startingPage "257" @default.
- W2014139218 abstract "To investigate the mechanism underlying the protective effects of glutaredoxin-1 (Grx1) against high glucose-induced apoptosis in umbilical vein endothelial cells. The proliferation of cells was measured by MTT assay. The cells ultra-structure were observed by TEM and the apoptotic rate was detected by the immunofluorescent of Annexin V－FITC/PI with flow cytometer. The level of p-JNK and JNK were evaluated by western bloting. Results showed that Grx1 prevented the inhibitory effect on cell viability induced by high glucose; Grxl could inhibit high glucose-induced apoptosis and restrain apoptosis rate of endothelial cell significantly. The expression level of p-JNK protein significantly increased while that of JNK protein has no insignificantly chang in cells of the high glucose group, After pretreatment with Grx1, the expression level of p-JNK protein decreased. These results demonstrated that Grx1 has protective effects against high glucose-induced apoptosis in HUVECs through inhibition of JNK pathway." @default.
- W2014139218 created "2016-06-24" @default.
- W2014139218 creator A5064584115 @default.
- W2014139218 creator A5068303224 @default.
- W2014139218 creator A5071875897 @default.
- W2014139218 date "2011-09-01" @default.
- W2014139218 modified "2023-09-28" @default.
- W2014139218 title "Grx1 Antagonized High Glucose-Induced Apoptosis in Endothelial Cells through Inhibition of Jnk Pathway" @default.
- W2014139218 cites W1975287242 @default.
- W2014139218 cites W1999070086 @default.
- W2014139218 cites W2005341765 @default.
- W2014139218 cites W2016847030 @default.
- W2014139218 cites W2020538411 @default.
- W2014139218 cites W2039499485 @default.
- W2014139218 cites W2039915647 @default.
- W2014139218 cites W2040468963 @default.
- W2014139218 cites W2041629346 @default.
- W2014139218 cites W2068864715 @default.
- W2014139218 cites W2089491860 @default.
- W2014139218 cites W2117812417 @default.
- W2014139218 cites W2129576311 @default.
- W2014139218 doi "https://doi.org/10.4028/www.scientific.net/amr.345.257" @default.
- W2014139218 hasPublicationYear "2011" @default.
- W2014139218 type Work @default.
- W2014139218 sameAs 2014139218 @default.
- W2014139218 citedByCount "0" @default.
- W2014139218 crossrefType "journal-article" @default.
- W2014139218 hasAuthorship W2014139218A5064584115 @default.
- W2014139218 hasAuthorship W2014139218A5068303224 @default.
- W2014139218 hasAuthorship W2014139218A5071875897 @default.
- W2014139218 hasConcept C153911025 @default.
- W2014139218 hasConcept C184235292 @default.
- W2014139218 hasConcept C185592680 @default.
- W2014139218 hasConcept C190283241 @default.
- W2014139218 hasConcept C202751555 @default.
- W2014139218 hasConcept C2777411675 @default.
- W2014139218 hasConcept C2780783641 @default.
- W2014139218 hasConcept C53009064 @default.
- W2014139218 hasConcept C53227056 @default.
- W2014139218 hasConcept C553184892 @default.
- W2014139218 hasConcept C55493867 @default.
- W2014139218 hasConcept C86803240 @default.
- W2014139218 hasConcept C88634738 @default.
- W2014139218 hasConcept C95444343 @default.
- W2014139218 hasConceptScore W2014139218C153911025 @default.
- W2014139218 hasConceptScore W2014139218C184235292 @default.
- W2014139218 hasConceptScore W2014139218C185592680 @default.
- W2014139218 hasConceptScore W2014139218C190283241 @default.
- W2014139218 hasConceptScore W2014139218C202751555 @default.
- W2014139218 hasConceptScore W2014139218C2777411675 @default.
- W2014139218 hasConceptScore W2014139218C2780783641 @default.
- W2014139218 hasConceptScore W2014139218C53009064 @default.
- W2014139218 hasConceptScore W2014139218C53227056 @default.
- W2014139218 hasConceptScore W2014139218C553184892 @default.
- W2014139218 hasConceptScore W2014139218C55493867 @default.
- W2014139218 hasConceptScore W2014139218C86803240 @default.
- W2014139218 hasConceptScore W2014139218C88634738 @default.
- W2014139218 hasConceptScore W2014139218C95444343 @default.
- W2014139218 hasLocation W20141392181 @default.
- W2014139218 hasOpenAccess W2014139218 @default.
- W2014139218 hasPrimaryLocation W20141392181 @default.
- W2014139218 hasRelatedWork W2347459042 @default.
- W2014139218 hasRelatedWork W2349733817 @default.
- W2014139218 hasRelatedWork W2353925213 @default.
- W2014139218 hasRelatedWork W2357419104 @default.
- W2014139218 hasRelatedWork W2358273413 @default.
- W2014139218 hasRelatedWork W2359728754 @default.
- W2014139218 hasRelatedWork W2359962157 @default.
- W2014139218 hasRelatedWork W2378294407 @default.
- W2014139218 hasRelatedWork W2385376622 @default.
- W2014139218 hasRelatedWork W3146609322 @default.
- W2014139218 hasVolume "345" @default.
- W2014139218 isParatext "false" @default.
- W2014139218 isRetracted "false" @default.
- W2014139218 magId "2014139218" @default.
- W2014139218 workType "article" @default.