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• W2014140131 abstract "On December 18, 2013 our facility treated the first patient using a single room Proton Therapy System. This followed seven months of acceptance testing and commissioning, which included; dosimetric data acquisition, safety checks, establishing quality assurance programs, mechanical and imaging checks, beam modeling validation, etc. Our single room system possesses a compact synchrocyclotron attached to a gantry due to its small size (1.8 m diameter) and light weight (22 tons). A 6D robotic couch allows beams for any trajectory. The current system customizes dose distribution using passive scattering (modulation and field size) according to an array of 24 options. The system provides 3D-2D imaging via fixed x-rays, with a portable CT arriving soon. Our treatment planning system is conducted with a commercial system. The electronic medical record system provides connectivity to the proton system, for setup, imaging, and treatment. The treatment planning modeling and validation met a gamma index goal of 1%, 1 mm for > 90% for all beam shaping system options (which are designed according to range). The exception is the first few centimeters of the buildup region, where a 3%/3 mm criteria was met. The imaging quality of the proton system surpassed expectations, for low and high contrast resolution, compared to baseline values of our current onboard imaging systems in our clinic. The measured isocentricity of the gantry and couch systems was measured to be 0.4 and 0.6 mm, respectively. The developed QA program includes daily checks for table isocentricity interlock, safety, imaging, and most importantly, dosimetric checks for three options. Daily, we measure output, modulation flatness, range, field symmetry, and distal falloff, all with a single exposure per option. The entire daily QA is performed in 30 minutes. The neutron dose was measured to be < 1.0 mSv/Gy for most clinical fields, alleviating concerns for pediatric treatments. Clinical start up over the first 2 months included a sampling of cases, namely; central nervous system (including a pediatric anesthesia case for medulloblastoma), pelvic chrondrosarcoma, esophagus, mediastinum, liver, etc. In terms of machine operation and reliability, the downtime has been 10% or less over the first 2 months. We are ramping up to 20 patients per day, with the case load depending on the number of anesthesia patients. All patients are currently planned with a backup treatment plan for IMRT or conventional therapy. This is performed in order to make proper planning comparisons, be available in case the proton machine has significant downtime, and for billing justification purposes. Overall, the single room proton therapy system has added a vital delivery option to compliment other treatment machines within our National Cancer Institute Comprehensive Center." @default.
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• W2014140131 date "2014-09-01" @default.
• W2014140131 modified "2023-09-27" @default.
• W2014140131 title "Technical and Clinical Experience With the First Single Room Proton Therapy System" @default.
• W2014140131 doi "https://doi.org/10.1016/j.ijrobp.2014.05.719" @default.
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