FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014144547> ?p ?o ?g. }

• W2014144547 endingPage "3058" @default.
• W2014144547 startingPage "3045" @default.
• W2014144547 abstract "A low-contrast spot that activates just one ganglion cell in the retina is detected in the spike train of the cell with about the same sensitivity as it is detected behaviorally. This is consistent with Barlow's proposal that the ganglion cell and later stages of spiking neurons transfer information essentially without loss. Yet, when losses of sensitivity by all preneural factors are accounted for, predicted sensitivity near threshold is considerably greater than behavioral sensitivity, implying that somewhere in the brain information is lost. We hypothesized that the losses occur mainly in the retina, where graded signals are processed by analog circuits that transfer information at high rates and low metabolic cost. To test this, we constructed a model that included all preneural losses for an in vitro mammalian retina, and evaluated the model to predict sensitivity at the cone output. Recording graded responses postsynaptic to the cones (from the type A horizontal cell) and comparing to predicted preneural sensitivity, we found substantial loss of sensitivity (4.2-fold) across the first visual synapse. Recording spike responses from brisk-transient ganglion cells stimulated with the same spot, we found a similar loss (3.5-fold) across the second synapse. The total retinal loss approximated the known overall loss, supporting the hypothesis that from stimulus to perception, most loss near threshold is retinal." @default.
• W2014144547 created "2016-06-24" @default.
• W2014144547 creator A5062533938 @default.
• W2014144547 creator A5062673695 @default.
• W2014144547 creator A5084891303 @default.
• W2014144547 date "2009-03-11" @default.
• W2014144547 modified "2023-09-27" @default.
• W2014144547 title "Loss of Sensitivity in an Analog Neural Circuit" @default.
• W2014144547 cites W1560544956 @default.
• W2014144547 cites W1627384048 @default.
• W2014144547 cites W1766518745 @default.
• W2014144547 cites W1874635627 @default.
• W2014144547 cites W1885775399 @default.
• W2014144547 cites W1910331461 @default.
• W2014144547 cites W1961799769 @default.
• W2014144547 cites W1963858199 @default.
• W2014144547 cites W1965666655 @default.
• W2014144547 cites W1970594452 @default.
• W2014144547 cites W1970892357 @default.
• W2014144547 cites W1971602201 @default.
• W2014144547 cites W1972954905 @default.
• W2014144547 cites W1975862239 @default.
• W2014144547 cites W1980823824 @default.
• W2014144547 cites W1982452461 @default.
• W2014144547 cites W1984579614 @default.
• W2014144547 cites W1990782412 @default.
• W2014144547 cites W1994606249 @default.
• W2014144547 cites W1994970646 @default.
• W2014144547 cites W1995043049 @default.
• W2014144547 cites W1996822428 @default.
• W2014144547 cites W1997986019 @default.
• W2014144547 cites W2003077859 @default.
• W2014144547 cites W2005979742 @default.
• W2014144547 cites W2007344132 @default.
• W2014144547 cites W2009133239 @default.
• W2014144547 cites W2009866472 @default.
• W2014144547 cites W2013239224 @default.
• W2014144547 cites W2015368612 @default.
• W2014144547 cites W2015872566 @default.
• W2014144547 cites W2023908419 @default.
• W2014144547 cites W2025396503 @default.
• W2014144547 cites W2027541804 @default.
• W2014144547 cites W2032977417 @default.
• W2014144547 cites W2042878307 @default.
• W2014144547 cites W2045048575 @default.
• W2014144547 cites W2045098012 @default.
• W2014144547 cites W2046075953 @default.
• W2014144547 cites W2059825364 @default.
• W2014144547 cites W2063438066 @default.
• W2014144547 cites W2067259649 @default.
• W2014144547 cites W2067622608 @default.
• W2014144547 cites W2070696598 @default.
• W2014144547 cites W2079721233 @default.
• W2014144547 cites W2080640045 @default.
• W2014144547 cites W2083549267 @default.
• W2014144547 cites W2083699254 @default.
• W2014144547 cites W2089565676 @default.
• W2014144547 cites W2092209687 @default.
• W2014144547 cites W2099406897 @default.
• W2014144547 cites W2105429189 @default.
• W2014144547 cites W2106081121 @default.
• W2014144547 cites W2106128024 @default.
• W2014144547 cites W2110090036 @default.
• W2014144547 cites W2110192752 @default.
• W2014144547 cites W2112455917 @default.
• W2014144547 cites W2114400482 @default.
• W2014144547 cites W2120106508 @default.
• W2014144547 cites W2125010820 @default.
• W2014144547 cites W2125277430 @default.
• W2014144547 cites W2137710832 @default.
• W2014144547 cites W2147492904 @default.
• W2014144547 cites W2148658703 @default.
• W2014144547 cites W2149838017 @default.
• W2014144547 cites W2150040413 @default.
• W2014144547 cites W2153050302 @default.
• W2014144547 cites W2163886718 @default.
• W2014144547 cites W2166742941 @default.
• W2014144547 cites W2404659340 @default.
• W2014144547 cites W2414338364 @default.
• W2014144547 doi "https://doi.org/10.1523/jneurosci.5071-08.2009" @default.
• W2014144547 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2818728" @default.
• W2014144547 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19279241" @default.
• W2014144547 hasPublicationYear "2009" @default.
• W2014144547 type Work @default.
• W2014144547 sameAs 2014144547 @default.
• W2014144547 citedByCount "33" @default.
• W2014144547 countsByYear W20141445472012 @default.
• W2014144547 countsByYear W20141445472013 @default.
• W2014144547 countsByYear W20141445472014 @default.
• W2014144547 countsByYear W20141445472015 @default.
• W2014144547 countsByYear W20141445472016 @default.
• W2014144547 countsByYear W20141445472017 @default.
• W2014144547 countsByYear W20141445472018 @default.
• W2014144547 countsByYear W20141445472020 @default.
• W2014144547 countsByYear W20141445472021 @default.
• W2014144547 countsByYear W20141445472022 @default.
• W2014144547 crossrefType "journal-article" @default.
• W2014144547 hasAuthorship W2014144547A5062533938 @default.

• next