FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014165281> ?p ?o ?g. }

• W2014165281 endingPage "1121" @default.
• W2014165281 startingPage "1117" @default.
• W2014165281 abstract "Amplification is one of the mechanisms by which cellular oncogenes may be altered in their function, possibly leading to neoplastic transformation. The oncogenes c-myc, c- abl , and c-Ki-ras are amplified in several different human neoplasias. The oncogene c-myb, which is specifically expressed and regulated in hematopoietic cells, was found to be amplified in cell lines ML-1, ML-2, and ML-3, which were separately cultured from cells of a patient with acute myelogenous leukemia (AML). A five- to tenfold amplification was correlated with high levels of expression of normal size c-myb messenger RNA and with chromosomal abnormalities in the region 6q22 -24, where the c-myb locus is normally located. Amplification and cytogenetic abnormalities were detected in DNA's from primary and secondary cultures of ML cells, suggesting that they may have contributed to leukemogenesis. The similar AML cell lines HL-60 and ML's contain different amplified oncogenes: c-myc and c-myb, respectively. Alternative activation of structurally and possibly functionally similar oncogenes may distinguish--at the pathogenetic level--phenotypically similar tumors." @default.
• W2014165281 created "2016-06-24" @default.
• W2014165281 creator A5003952691 @default.
• W2014165281 creator A5012955086 @default.
• W2014165281 creator A5018152971 @default.
• W2014165281 creator A5028673758 @default.
• W2014165281 creator A5057101865 @default.
• W2014165281 date "1984-06-08" @default.
• W2014165281 modified "2023-10-16" @default.
• W2014165281 title "Amplification of the c- <i>myb</i> Oncogene in a Case of Human Acute Myelogenous Leukemia" @default.
• W2014165281 cites W1965975157 @default.
• W2014165281 cites W1966730043 @default.
• W2014165281 cites W1967072335 @default.
• W2014165281 cites W1967606691 @default.
• W2014165281 cites W1987234748 @default.
• W2014165281 cites W1987600685 @default.
• W2014165281 cites W2012850212 @default.
• W2014165281 cites W2013609014 @default.
• W2014165281 cites W2014520088 @default.
• W2014165281 cites W2017692699 @default.
• W2014165281 cites W2029987769 @default.
• W2014165281 cites W2032972450 @default.
• W2014165281 cites W2047343417 @default.
• W2014165281 cites W2048324748 @default.
• W2014165281 cites W2056120923 @default.
• W2014165281 cites W2063450941 @default.
• W2014165281 cites W2064735501 @default.
• W2014165281 cites W2065772234 @default.
• W2014165281 cites W2072262157 @default.
• W2014165281 cites W2076971412 @default.
• W2014165281 cites W2084984946 @default.
• W2014165281 cites W2085214231 @default.
• W2014165281 cites W2092299362 @default.
• W2014165281 cites W2093310753 @default.
• W2014165281 cites W2102838769 @default.
• W2014165281 cites W2180795626 @default.
• W2014165281 cites W2241139343 @default.
• W2014165281 doi "https://doi.org/10.1126/science.6585957" @default.
• W2014165281 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6585957" @default.
• W2014165281 hasPublicationYear "1984" @default.
• W2014165281 type Work @default.
• W2014165281 sameAs 2014165281 @default.
• W2014165281 citedByCount "166" @default.
• W2014165281 countsByYear W20141652812012 @default.
• W2014165281 countsByYear W20141652812013 @default.
• W2014165281 countsByYear W20141652812014 @default.
• W2014165281 countsByYear W20141652812017 @default.
• W2014165281 countsByYear W20141652812018 @default.
• W2014165281 countsByYear W20141652812019 @default.
• W2014165281 countsByYear W20141652812021 @default.
• W2014165281 countsByYear W20141652812023 @default.
• W2014165281 crossrefType "journal-article" @default.
• W2014165281 hasAuthorship W2014165281A5003952691 @default.
• W2014165281 hasAuthorship W2014165281A5012955086 @default.
• W2014165281 hasAuthorship W2014165281A5018152971 @default.
• W2014165281 hasAuthorship W2014165281A5028673758 @default.
• W2014165281 hasAuthorship W2014165281A5057101865 @default.
• W2014165281 hasConcept C104317684 @default.
• W2014165281 hasConcept C109159458 @default.
• W2014165281 hasConcept C1491633281 @default.
• W2014165281 hasConcept C150194340 @default.
• W2014165281 hasConcept C153911025 @default.
• W2014165281 hasConcept C2776960273 @default.
• W2014165281 hasConcept C2778461978 @default.
• W2014165281 hasConcept C2781018059 @default.
• W2014165281 hasConcept C28328180 @default.
• W2014165281 hasConcept C2911062167 @default.
• W2014165281 hasConcept C29537977 @default.
• W2014165281 hasConcept C2993273003 @default.
• W2014165281 hasConcept C502942594 @default.
• W2014165281 hasConcept C54355233 @default.
• W2014165281 hasConcept C555283112 @default.
• W2014165281 hasConcept C62794011 @default.
• W2014165281 hasConcept C7602840 @default.
• W2014165281 hasConcept C81885089 @default.
• W2014165281 hasConcept C84597430 @default.
• W2014165281 hasConcept C86803240 @default.
• W2014165281 hasConceptScore W2014165281C104317684 @default.
• W2014165281 hasConceptScore W2014165281C109159458 @default.
• W2014165281 hasConceptScore W2014165281C1491633281 @default.
• W2014165281 hasConceptScore W2014165281C150194340 @default.
• W2014165281 hasConceptScore W2014165281C153911025 @default.
• W2014165281 hasConceptScore W2014165281C2776960273 @default.
• W2014165281 hasConceptScore W2014165281C2778461978 @default.
• W2014165281 hasConceptScore W2014165281C2781018059 @default.
• W2014165281 hasConceptScore W2014165281C28328180 @default.
• W2014165281 hasConceptScore W2014165281C2911062167 @default.
• W2014165281 hasConceptScore W2014165281C29537977 @default.
• W2014165281 hasConceptScore W2014165281C2993273003 @default.
• W2014165281 hasConceptScore W2014165281C502942594 @default.
• W2014165281 hasConceptScore W2014165281C54355233 @default.
• W2014165281 hasConceptScore W2014165281C555283112 @default.
• W2014165281 hasConceptScore W2014165281C62794011 @default.
• W2014165281 hasConceptScore W2014165281C7602840 @default.
• W2014165281 hasConceptScore W2014165281C81885089 @default.
• W2014165281 hasConceptScore W2014165281C84597430 @default.
• W2014165281 hasConceptScore W2014165281C86803240 @default.
• W2014165281 hasIssue "4653" @default.

• next