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- W2014166320 abstract "Atherosclerosis remains the leading cause of death worldwide, and although the underlying pathophysiology is incompletely understood, it is increasingly viewed as an inflammatory condition.1 Indeed, levels of circulating white cells and inflammatory mediators, such as C-reactive protein (CRP) and interleukin-6 (IL-6), are raised in patients with cardiovascular disease, and in those with cardiovascular risk factors, including a family history of premature cardiovascular disease.2 Moreover, when assessed with highly sensitive assays, CRP levels independently predict outcome in patients with coronary heart disease,3, 4 and in apparently healthy individuals.5, 6 More direct evidence concerning the role of inflammation in atheroma formation comes from in vitro studies and animal models of atherosclerosis.1" @default.
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- W2014166320 date "2005-01-13" @default.
- W2014166320 modified "2023-09-27" @default.
- W2014166320 title "Large artery stiffness and inflammation" @default.
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- W2014166320 doi "https://doi.org/10.1038/sj.jhh.1001814" @default.
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