FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014183716> ?p ?o ?g. }

• W2014183716 endingPage "39" @default.
• W2014183716 startingPage "19" @default.
• W2014183716 abstract "The literature reviewed here is consistent in showing that GAD is a common mental disorder that typically has an early age of onset, a chronic course, and a high degree of comorbidity with other anxiety and mood disorders. Comorbid GAD is often temporally primary, especially in relation to mood disorders, and is associated with an increased risk for the subsequent onset and severity of secondary disorders. The weight of evidence reviewed here argues against the view expressed by early commentators that GAD is better conceptualized as a prodrome, residual, or severity marker of other disorders than as an independent disorder. Focused studies of comorbidity between GAD and major depression, in which comorbidity is high, lead to the same conclusion. The crucial evidence for this conclusion includes the following: 1. Contrary to the findings of clinical studies, GAD in the community does not have a higher comorbidity than do most other anxiety or mood disorders. 2. The symptoms of GAD form an empiric cluster distinct from the symptoms of major depression in studies of symptom profiles. 3. Family studies show distinct aggregation of GAD and major depression. 4. Twin studies show that the environmental determinants of GAD are different from the environmental determinants of major depression. 5. The sociodemographic predictors of GAD in epidemiologic studies are different from the predictors of major depression. 6. The clinical course of GAD is less consistently related to comorbidity than is the course of other anxiety and mood disorders. 7. The impairments associated with GAD are equivalent to, or greater than, those associated with other severely impairing chronic physical and mental disorders. These findings show that the status of GAD as an independent disorder is at least as strongly supported by available evidence as is that of other anxiety or mood disorders. This article also shows that uncertainty remains regarding even the basic epidemiologic characteristics of the GAD syndrome. Lingering concerns about the independence of GAD have conspired to exacerbate this problem by promoting repeated changes in the diagnostic criteria for GAD from the DSM-III to DSM-III-R and to DSM-IV. These successive changes have made it difficult to amass consistent long-term data on the natural history of GAD. Available evidence on the empiric validity of current diagnostic thresholds for GAD raises questions about the requirements, such as whether a 6-month minimum duration and four or more additional psychophysiologic symptoms are optimal for identifying all of the people in the general population who suffer from a clinically significant GAD syndrome. An additional source of potential bias in this regard is that the DSM system requires that anxiety be excessive or unrealistic for a diagnosis of GAD. Interestingly, there is no comparable DSM requirement that dysphoria must be excessive or unrealistic to qualify as major depression. These diagnostic uncertainties make it difficult to gain a clear understanding of the true breadth and depth of the GAD syndrome in the general population. Additional research is needed, ideally from unbiased epidemiologic samples, to resolve these basic uncertainties. The strong comorbidity between GAD and major depression, the fact that most people with this type of comorbidity report that the onset of GAD occurred before the onset of depression, and the fact that temporally primary GAD significantly predicts the subsequent onset of depression and other secondary disorders raise the question of whether early intervention and treatment of primary GAD would effectively prevent the subsequent first onset of secondary anxiety and depression. Unfortunately, little is known about this possibility because, as mentioned earlier, few people with pure GAD seek treatment. Why this is true is unknown. Given the early onset of GAD and its strong effects in predicting the subsequent onset, severity, and persistence of other disorders, efforts are needed to collect epidemiologic data on the reasons for the low rate of help seeking among people with pure GAD and to develop outreach strategies that may correct this situation." @default.
• W2014183716 created "2016-06-24" @default.
• W2014183716 creator A5011774503 @default.
• W2014183716 creator A5057810294 @default.
• W2014183716 creator A5080980894 @default.
• W2014183716 date "2001-03-01" @default.
• W2014183716 modified "2023-10-17" @default.
• W2014183716 title "The Epidemiology of Generalized Anxiety Disorder" @default.
• W2014183716 cites W1506951524 @default.
• W2014183716 cites W1599530923 @default.
• W2014183716 cites W1972153662 @default.
• W2014183716 cites W1972523301 @default.
• W2014183716 cites W1981272264 @default.
• W2014183716 cites W1982394613 @default.
• W2014183716 cites W1983230895 @default.
• W2014183716 cites W1991434331 @default.
• W2014183716 cites W2009401947 @default.
• W2014183716 cites W2011526819 @default.
• W2014183716 cites W2012453547 @default.
• W2014183716 cites W2033465807 @default.
• W2014183716 cites W2037875799 @default.
• W2014183716 cites W2047605192 @default.
• W2014183716 cites W2048805963 @default.
• W2014183716 cites W2052814365 @default.
• W2014183716 cites W2054298209 @default.
• W2014183716 cites W2054466148 @default.
• W2014183716 cites W2059299715 @default.
• W2014183716 cites W2066687592 @default.
• W2014183716 cites W2074373409 @default.
• W2014183716 cites W2078004522 @default.
• W2014183716 cites W2079105789 @default.
• W2014183716 cites W2081726701 @default.
• W2014183716 cites W2082536055 @default.
• W2014183716 cites W2090310653 @default.
• W2014183716 cites W2093952440 @default.
• W2014183716 cites W2106387734 @default.
• W2014183716 cites W2122910838 @default.
• W2014183716 cites W2125457472 @default.
• W2014183716 cites W2136763752 @default.
• W2014183716 cites W2152313268 @default.
• W2014183716 cites W2154049245 @default.
• W2014183716 cites W2156000474 @default.
• W2014183716 cites W2159061031 @default.
• W2014183716 cites W2162455435 @default.
• W2014183716 cites W2400600349 @default.
• W2014183716 cites W2409643143 @default.
• W2014183716 cites W2413307415 @default.
• W2014183716 cites W2885386535 @default.
• W2014183716 cites W4206621253 @default.
• W2014183716 cites W4232783226 @default.
• W2014183716 cites W4256384952 @default.
• W2014183716 cites W4295836678 @default.
• W2014183716 cites W58497068 @default.
• W2014183716 doi "https://doi.org/10.1016/s0193-953x(05)70204-5" @default.
• W2014183716 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11225507" @default.
• W2014183716 hasPublicationYear "2001" @default.
• W2014183716 type Work @default.
• W2014183716 sameAs 2014183716 @default.
• W2014183716 citedByCount "282" @default.
• W2014183716 countsByYear W20141837162012 @default.
• W2014183716 countsByYear W20141837162013 @default.
• W2014183716 countsByYear W20141837162014 @default.
• W2014183716 countsByYear W20141837162015 @default.
• W2014183716 countsByYear W20141837162016 @default.
• W2014183716 countsByYear W20141837162017 @default.
• W2014183716 countsByYear W20141837162018 @default.
• W2014183716 countsByYear W20141837162019 @default.
• W2014183716 countsByYear W20141837162020 @default.
• W2014183716 countsByYear W20141837162021 @default.
• W2014183716 countsByYear W20141837162022 @default.
• W2014183716 countsByYear W20141837162023 @default.
• W2014183716 crossrefType "journal-article" @default.
• W2014183716 hasAuthorship W2014183716A5011774503 @default.
• W2014183716 hasAuthorship W2014183716A5057810294 @default.
• W2014183716 hasAuthorship W2014183716A5080980894 @default.
• W2014183716 hasConcept C118552586 @default.
• W2014183716 hasConcept C139719470 @default.
• W2014183716 hasConcept C15744967 @default.
• W2014183716 hasConcept C162324750 @default.
• W2014183716 hasConcept C2776317618 @default.
• W2014183716 hasConcept C2776867660 @default.
• W2014183716 hasConcept C2777134132 @default.
• W2014183716 hasConcept C2779159551 @default.
• W2014183716 hasConcept C2779911313 @default.
• W2014183716 hasConcept C2780733359 @default.
• W2014183716 hasConcept C558461103 @default.
• W2014183716 hasConcept C70410870 @default.
• W2014183716 hasConceptScore W2014183716C118552586 @default.
• W2014183716 hasConceptScore W2014183716C139719470 @default.
• W2014183716 hasConceptScore W2014183716C15744967 @default.
• W2014183716 hasConceptScore W2014183716C162324750 @default.
• W2014183716 hasConceptScore W2014183716C2776317618 @default.
• W2014183716 hasConceptScore W2014183716C2776867660 @default.
• W2014183716 hasConceptScore W2014183716C2777134132 @default.
• W2014183716 hasConceptScore W2014183716C2779159551 @default.
• W2014183716 hasConceptScore W2014183716C2779911313 @default.
• W2014183716 hasConceptScore W2014183716C2780733359 @default.
• W2014183716 hasConceptScore W2014183716C558461103 @default.

• next