FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014185148> ?p ?o ?g. }

• W2014185148 endingPage "313" @default.
• W2014185148 startingPage "308" @default.
• W2014185148 abstract "Free choline and ATP contents were measured in Mongolian gerbil hippocampal slices (tissue) and incubation media (media) during exposure to 30 min of aglycemia, high potassium, anoxia, or ischemia. Changes in choline levels reflected the degree of energy reduction, lower ATP levels being associated with high choline (4-fold increase during exposure to high potassium and anoxia, and 11-fold increase during ischemia). Media (extracellular) choline was particularly affected and increased about twofold during relatively mild energy depletion (e.g., aglycemia), but tissue choline content was less sensitive to energy reduction. A plot of choline vs. ATP levels indicated a nonlinear correlation, and the sharp increase in choline occurred when ATP values fell to about 2.5 nmol/mg of protein. Inhibition of acetylcholine sterase by 10 μ M physostigmine during ischemia did not prevent an increase in choline contents but rather enhanced them, indicating that acetylcholine hydrolysis was not the source of free choline. Formation of free choline was Ca 2+ independent. These findings suggest the involvement of phospholipase D and phosphatidylcholine hydrolysis in free choline formation during energy stress. The extent of choline formation may be an indicator of the degree of membranal damage, which in turn reflects damage to the metabolic machinery of the cell." @default.
• W2014185148 created "2016-06-24" @default.
• W2014185148 creator A5005025137 @default.
• W2014185148 creator A5034765332 @default.
• W2014185148 creator A5039796116 @default.
• W2014185148 creator A5078400003 @default.
• W2014185148 creator A5082098079 @default.
• W2014185148 creator A5089376195 @default.
• W2014185148 date "1991-03-01" @default.
• W2014185148 modified "2023-10-16" @default.
• W2014185148 title "Formation of Free Choline in Brain Tissue during in vitro Energy Deprivation" @default.
• W2014185148 cites W1515652814 @default.
• W2014185148 cites W1536640324 @default.
• W2014185148 cites W1541054247 @default.
• W2014185148 cites W1561066485 @default.
• W2014185148 cites W1578978258 @default.
• W2014185148 cites W1775749144 @default.
• W2014185148 cites W1899736663 @default.
• W2014185148 cites W1929378679 @default.
• W2014185148 cites W1965724936 @default.
• W2014185148 cites W1968220296 @default.
• W2014185148 cites W1995875098 @default.
• W2014185148 cites W2009888614 @default.
• W2014185148 cites W2025246061 @default.
• W2014185148 cites W2052942712 @default.
• W2014185148 cites W2053998523 @default.
• W2014185148 cites W2055562254 @default.
• W2014185148 cites W2056204674 @default.
• W2014185148 cites W2056734745 @default.
• W2014185148 cites W2068025501 @default.
• W2014185148 cites W2077196081 @default.
• W2014185148 cites W2078143043 @default.
• W2014185148 cites W2078237283 @default.
• W2014185148 cites W2081720076 @default.
• W2014185148 cites W2084951485 @default.
• W2014185148 cites W2085382074 @default.
• W2014185148 cites W2087421641 @default.
• W2014185148 cites W2105705623 @default.
• W2014185148 cites W2108816191 @default.
• W2014185148 cites W2117594247 @default.
• W2014185148 cites W2130694858 @default.
• W2014185148 cites W2137750395 @default.
• W2014185148 cites W2138948431 @default.
• W2014185148 cites W4249680115 @default.
• W2014185148 doi "https://doi.org/10.1038/jcbfm.1991.63" @default.
• W2014185148 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1997502" @default.
• W2014185148 hasPublicationYear "1991" @default.
• W2014185148 type Work @default.
• W2014185148 sameAs 2014185148 @default.
• W2014185148 citedByCount "71" @default.
• W2014185148 countsByYear W20141851482012 @default.
• W2014185148 countsByYear W20141851482013 @default.
• W2014185148 countsByYear W20141851482014 @default.
• W2014185148 countsByYear W20141851482015 @default.
• W2014185148 countsByYear W20141851482016 @default.
• W2014185148 countsByYear W20141851482017 @default.
• W2014185148 countsByYear W20141851482018 @default.
• W2014185148 countsByYear W20141851482021 @default.
• W2014185148 countsByYear W20141851482022 @default.
• W2014185148 countsByYear W20141851482023 @default.
• W2014185148 crossrefType "journal-article" @default.
• W2014185148 hasAuthorship W2014185148A5005025137 @default.
• W2014185148 hasAuthorship W2014185148A5034765332 @default.
• W2014185148 hasAuthorship W2014185148A5039796116 @default.
• W2014185148 hasAuthorship W2014185148A5078400003 @default.
• W2014185148 hasAuthorship W2014185148A5082098079 @default.
• W2014185148 hasAuthorship W2014185148A5089376195 @default.
• W2014185148 hasBestOaLocation W20141851481 @default.
• W2014185148 hasConcept C126322002 @default.
• W2014185148 hasConcept C134018914 @default.
• W2014185148 hasConcept C178790620 @default.
• W2014185148 hasConcept C185592680 @default.
• W2014185148 hasConcept C2775910092 @default.
• W2014185148 hasConcept C2776330855 @default.
• W2014185148 hasConcept C2776923060 @default.
• W2014185148 hasConcept C2778375661 @default.
• W2014185148 hasConcept C2778918659 @default.
• W2014185148 hasConcept C2781123555 @default.
• W2014185148 hasConcept C28406088 @default.
• W2014185148 hasConcept C41625074 @default.
• W2014185148 hasConcept C517785266 @default.
• W2014185148 hasConcept C541997718 @default.
• W2014185148 hasConcept C55493867 @default.
• W2014185148 hasConcept C71924100 @default.
• W2014185148 hasConcept C79879829 @default.
• W2014185148 hasConcept C86803240 @default.
• W2014185148 hasConceptScore W2014185148C126322002 @default.
• W2014185148 hasConceptScore W2014185148C134018914 @default.
• W2014185148 hasConceptScore W2014185148C178790620 @default.
• W2014185148 hasConceptScore W2014185148C185592680 @default.
• W2014185148 hasConceptScore W2014185148C2775910092 @default.
• W2014185148 hasConceptScore W2014185148C2776330855 @default.
• W2014185148 hasConceptScore W2014185148C2776923060 @default.
• W2014185148 hasConceptScore W2014185148C2778375661 @default.
• W2014185148 hasConceptScore W2014185148C2778918659 @default.
• W2014185148 hasConceptScore W2014185148C2781123555 @default.
• W2014185148 hasConceptScore W2014185148C28406088 @default.
• W2014185148 hasConceptScore W2014185148C41625074 @default.

• next