FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014194877> ?p ?o ?g. }

• W2014194877 endingPage "9768" @default.
• W2014194877 startingPage "9760" @default.
• W2014194877 abstract "The adsorption of proteins at material surfaces is important in applications such as biomaterials, drug delivery, and diagnostics. The interaction of cells with artificial surfaces is mediated through adsorbed proteins, where the type of protein, amount, orientation, and conformation are of consequence for the cell response. Laminin, an important cell adhesive protein that is central in developmental biology, is studied by a combination of quartz crystal microbalance with dissipation (QCM-D) and surface plasmon resonance (SPR) to characterize the adsorption of laminin on surfaces of different surface chemistries. The combination of these two techniques allows for the determination of the thickness and effective density of the protein layer as well as the adsorbed mass and viscoelastic properties. We also evaluate the capacity of QCM-D to be used as a quantitative technique on a nanostructured surface, where protein is adsorbed specifically in a nanopattern exploiting PLL-g-PEG as a protein-resistant background. We show that laminin forms a highly hydrated protein layer with different characteristics depending on the underlying substrate. Using a combination of QCM-D and atomic force microscopy (AFM) data from nanostructured surfaces, we model laminin and antibody binding to nanometer-scale patches. A higher amount of laminin was found to adsorb in a thicker layer of a lower effective density in nanopatches compared to equivalent homogeneous surfaces. These results suggest that modeling of QCM-D data of soft viscoelastic layers arranged in nanopatterns may be applied where an independent measure of the dry mass is known." @default.
• W2014194877 created "2016-06-24" @default.
• W2014194877 creator A5017738117 @default.
• W2014194877 creator A5034450047 @default.
• W2014194877 creator A5072941608 @default.
• W2014194877 creator A5084929010 @default.
• W2014194877 date "2007-08-11" @default.
• W2014194877 modified "2023-10-14" @default.
• W2014194877 title "Viscoelastic Modeling of Highly Hydrated Laminin Layers at Homogeneous and Nanostructured Surfaces: Quantification of Protein Layer Properties Using QCM-D and SPR" @default.
• W2014194877 cites W1970004609 @default.
• W2014194877 cites W1974107311 @default.
• W2014194877 cites W1992615890 @default.
• W2014194877 cites W2000955544 @default.
• W2014194877 cites W2001553792 @default.
• W2014194877 cites W2004391976 @default.
• W2014194877 cites W2004581068 @default.
• W2014194877 cites W2005756613 @default.
• W2014194877 cites W2007808060 @default.
• W2014194877 cites W2013481880 @default.
• W2014194877 cites W2013960477 @default.
• W2014194877 cites W2015115704 @default.
• W2014194877 cites W2015562860 @default.
• W2014194877 cites W2023135762 @default.
• W2014194877 cites W2025865127 @default.
• W2014194877 cites W2033776226 @default.
• W2014194877 cites W2035236528 @default.
• W2014194877 cites W2036374139 @default.
• W2014194877 cites W2048287289 @default.
• W2014194877 cites W2048289350 @default.
• W2014194877 cites W2063233815 @default.
• W2014194877 cites W2079356804 @default.
• W2014194877 cites W2087000111 @default.
• W2014194877 cites W2090684107 @default.
• W2014194877 cites W2091306163 @default.
• W2014194877 cites W2130150908 @default.
• W2014194877 cites W2142153502 @default.
• W2014194877 cites W2149482213 @default.
• W2014194877 cites W2329764685 @default.
• W2014194877 cites W2599199563 @default.
• W2014194877 cites W4254103178 @default.
• W2014194877 doi "https://doi.org/10.1021/la701233y" @default.
• W2014194877 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17691829" @default.
• W2014194877 hasPublicationYear "2007" @default.
• W2014194877 type Work @default.
• W2014194877 sameAs 2014194877 @default.
• W2014194877 citedByCount "140" @default.
• W2014194877 countsByYear W20141948772012 @default.
• W2014194877 countsByYear W20141948772013 @default.
• W2014194877 countsByYear W20141948772014 @default.
• W2014194877 countsByYear W20141948772015 @default.
• W2014194877 countsByYear W20141948772016 @default.
• W2014194877 countsByYear W20141948772017 @default.
• W2014194877 countsByYear W20141948772018 @default.
• W2014194877 countsByYear W20141948772019 @default.
• W2014194877 countsByYear W20141948772020 @default.
• W2014194877 countsByYear W20141948772021 @default.
• W2014194877 countsByYear W20141948772022 @default.
• W2014194877 countsByYear W20141948772023 @default.
• W2014194877 crossrefType "journal-article" @default.
• W2014194877 hasAuthorship W2014194877A5017738117 @default.
• W2014194877 hasAuthorship W2014194877A5034450047 @default.
• W2014194877 hasAuthorship W2014194877A5072941608 @default.
• W2014194877 hasAuthorship W2014194877A5084929010 @default.
• W2014194877 hasConcept C106847996 @default.
• W2014194877 hasConcept C12554922 @default.
• W2014194877 hasConcept C127413603 @default.
• W2014194877 hasConcept C1491633281 @default.
• W2014194877 hasConcept C150394285 @default.
• W2014194877 hasConcept C155672457 @default.
• W2014194877 hasConcept C159985019 @default.
• W2014194877 hasConcept C171250308 @default.
• W2014194877 hasConcept C178790620 @default.
• W2014194877 hasConcept C185592680 @default.
• W2014194877 hasConcept C186541917 @default.
• W2014194877 hasConcept C192562407 @default.
• W2014194877 hasConcept C2779227376 @default.
• W2014194877 hasConcept C2779814568 @default.
• W2014194877 hasConcept C42360764 @default.
• W2014194877 hasConcept C55493867 @default.
• W2014194877 hasConcept C86803240 @default.
• W2014194877 hasConcept C88001094 @default.
• W2014194877 hasConcept C9996572 @default.
• W2014194877 hasConceptScore W2014194877C106847996 @default.
• W2014194877 hasConceptScore W2014194877C12554922 @default.
• W2014194877 hasConceptScore W2014194877C127413603 @default.
• W2014194877 hasConceptScore W2014194877C1491633281 @default.
• W2014194877 hasConceptScore W2014194877C150394285 @default.
• W2014194877 hasConceptScore W2014194877C155672457 @default.
• W2014194877 hasConceptScore W2014194877C159985019 @default.
• W2014194877 hasConceptScore W2014194877C171250308 @default.
• W2014194877 hasConceptScore W2014194877C178790620 @default.
• W2014194877 hasConceptScore W2014194877C185592680 @default.
• W2014194877 hasConceptScore W2014194877C186541917 @default.
• W2014194877 hasConceptScore W2014194877C192562407 @default.
• W2014194877 hasConceptScore W2014194877C2779227376 @default.
• W2014194877 hasConceptScore W2014194877C2779814568 @default.
• W2014194877 hasConceptScore W2014194877C42360764 @default.
• W2014194877 hasConceptScore W2014194877C55493867 @default.

• next