Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014207369> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2014207369 endingPage "230" @default.
- W2014207369 startingPage "225" @default.
- W2014207369 abstract "Mechanosensitive currents in cultured rat dorsal root ganglion (DRG) neurons were analyzed by whole-cell patch clamp experiments. A positive pressure applied through a patch electrode induced an inward current in neurons 20 microm or larger in diameter. Ca(2+)- and Na(+)-depletion experiments revealed two kinds of channels involved in the mechanotransduction. One type of cells (type A) displayed blockade of the inward current in the absence of external Ca(2+); namely, the positive pressure of 10 cmH(2)O induced an inward current of 0.45+/-0.14 nA (mean+/-S.D., n=6) in the normal medium, and 0.08+/-0.07 nA (n=6) in the Ca(2+)-free solution. The current was influenced only a little by the depletion of external Na(+) in type A; the positive pressure induced an inward current of 0.48+/-0.04 nA (n=6) in the normal medium, and 0.39+/-0.06 nA (n=6) in the Na(+)-free solution. In the other type of cells (type B), the current persisted in the absence of Ca(2+); 0.52+/-0.09 nA (n=6) in the normal medium, and 0.35+/-0.09 nA (n=6) in the Ca(2+)-free solution. This type displayed a significant decrease in the inward current in the absence of Na(+); 0.42+/-0.09 nA (n=6) in the normal medium, and 0.23+/-0.08 nA (n=6) in the Na(+)-free solution. We concluded that there are two types of mechanosensitive channels in cultured DRG neurons, a Ca(2+)-selective channel and a non-selective cation channel." @default.
- W2014207369 created "2016-06-24" @default.
- W2014207369 creator A5058850758 @default.
- W2014207369 creator A5070434951 @default.
- W2014207369 date "2000-06-01" @default.
- W2014207369 modified "2023-09-27" @default.
- W2014207369 title "Mechanosensitive whole-cell currents in cultured rat somatosensory neurons" @default.
- W2014207369 cites W1971077634 @default.
- W2014207369 cites W1980361075 @default.
- W2014207369 cites W1980558682 @default.
- W2014207369 cites W1990711883 @default.
- W2014207369 cites W1992469700 @default.
- W2014207369 cites W2004084338 @default.
- W2014207369 cites W2008790997 @default.
- W2014207369 cites W2009568139 @default.
- W2014207369 cites W2020452164 @default.
- W2014207369 cites W2026903272 @default.
- W2014207369 cites W2030697223 @default.
- W2014207369 cites W2030854550 @default.
- W2014207369 cites W2037661033 @default.
- W2014207369 cites W2044683483 @default.
- W2014207369 cites W2052127909 @default.
- W2014207369 cites W2052630699 @default.
- W2014207369 cites W2053908537 @default.
- W2014207369 cites W2086354121 @default.
- W2014207369 cites W2114367454 @default.
- W2014207369 cites W2121349030 @default.
- W2014207369 cites W2125942201 @default.
- W2014207369 cites W2233524966 @default.
- W2014207369 cites W2344165305 @default.
- W2014207369 cites W2404215415 @default.
- W2014207369 doi "https://doi.org/10.1016/s0006-8993(00)02366-0" @default.
- W2014207369 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10865079" @default.
- W2014207369 hasPublicationYear "2000" @default.
- W2014207369 type Work @default.
- W2014207369 sameAs 2014207369 @default.
- W2014207369 citedByCount "21" @default.
- W2014207369 countsByYear W20142073692012 @default.
- W2014207369 countsByYear W20142073692014 @default.
- W2014207369 crossrefType "journal-article" @default.
- W2014207369 hasAuthorship W2014207369A5058850758 @default.
- W2014207369 hasAuthorship W2014207369A5070434951 @default.
- W2014207369 hasConcept C105702510 @default.
- W2014207369 hasConcept C12554922 @default.
- W2014207369 hasConcept C140530291 @default.
- W2014207369 hasConcept C147944092 @default.
- W2014207369 hasConcept C169760540 @default.
- W2014207369 hasConcept C170493617 @default.
- W2014207369 hasConcept C172497186 @default.
- W2014207369 hasConcept C185263204 @default.
- W2014207369 hasConcept C185592680 @default.
- W2014207369 hasConcept C2776281502 @default.
- W2014207369 hasConcept C4001165 @default.
- W2014207369 hasConcept C50254741 @default.
- W2014207369 hasConcept C55493867 @default.
- W2014207369 hasConcept C86803240 @default.
- W2014207369 hasConceptScore W2014207369C105702510 @default.
- W2014207369 hasConceptScore W2014207369C12554922 @default.
- W2014207369 hasConceptScore W2014207369C140530291 @default.
- W2014207369 hasConceptScore W2014207369C147944092 @default.
- W2014207369 hasConceptScore W2014207369C169760540 @default.
- W2014207369 hasConceptScore W2014207369C170493617 @default.
- W2014207369 hasConceptScore W2014207369C172497186 @default.
- W2014207369 hasConceptScore W2014207369C185263204 @default.
- W2014207369 hasConceptScore W2014207369C185592680 @default.
- W2014207369 hasConceptScore W2014207369C2776281502 @default.
- W2014207369 hasConceptScore W2014207369C4001165 @default.
- W2014207369 hasConceptScore W2014207369C50254741 @default.
- W2014207369 hasConceptScore W2014207369C55493867 @default.
- W2014207369 hasConceptScore W2014207369C86803240 @default.
- W2014207369 hasIssue "1-2" @default.
- W2014207369 hasLocation W20142073691 @default.
- W2014207369 hasLocation W20142073692 @default.
- W2014207369 hasOpenAccess W2014207369 @default.
- W2014207369 hasPrimaryLocation W20142073691 @default.
- W2014207369 hasRelatedWork W2060407010 @default.
- W2014207369 hasRelatedWork W211956868 @default.
- W2014207369 hasRelatedWork W2128490730 @default.
- W2014207369 hasRelatedWork W2148347482 @default.
- W2014207369 hasRelatedWork W2370587666 @default.
- W2014207369 hasRelatedWork W2396224357 @default.
- W2014207369 hasRelatedWork W2417736758 @default.
- W2014207369 hasRelatedWork W3010909472 @default.
- W2014207369 hasRelatedWork W3120446790 @default.
- W2014207369 hasRelatedWork W4282934577 @default.
- W2014207369 hasVolume "869" @default.
- W2014207369 isParatext "false" @default.
- W2014207369 isRetracted "false" @default.
- W2014207369 magId "2014207369" @default.
- W2014207369 workType "article" @default.