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• W2014209528 endingPage "87" @default.
• W2014209528 startingPage "80" @default.
• W2014209528 abstract "Mitotic Centromere Associated Kinesin (MCAK) is a potent microtubule depolymerizing and catastrophe-inducing factor, which uses the energy of ATP hydrolysis to destabilize microtubule ends. MCAK is localized to inner centromeres, kinetochores and spindle poles of mitotic cells, and is also present in the cytoplasm. Both in interphase and in mitosis, MCAK can specifically accumulate at the growing microtubule ends. Here we discuss the mechanisms, which modulate subcellular localization and activity of MCAK through the interaction with the End Binding (EB) proteins and phosphorylation." @default.
• W2014209528 created "2016-06-24" @default.
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• W2014209528 creator A5074565662 @default.
• W2014209528 date "2011-03-01" @default.
• W2014209528 modified "2023-09-30" @default.
• W2014209528 title "Regulation of localization and activity of the microtubule depolymerase MCAK" @default.
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• W2014209528 doi "https://doi.org/10.4161/bioa.1.2.15807" @default.
• W2014209528 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3158623" @default.
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