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- W2014218809 abstract "The effect of different groups of psychotropic agents on the spontaneous absence-like paroxysms in the ECoG of rats was studied in order to evaluate the specificity of the model for antiabsence drugs. Morphine-like analgesics increased the number of paroxysms, whereas this was depressed or the discharges were completely abolished by the following drugs:d-amphetamine, tricyclic antidepressants, centrally acting anticholinergics and l-DOPA, NMDA antagonists and memantine. Since the latter drugs have been reported to be effective in petit mal epilepsy, or the NMDA antagonists and memantine, have a potential anticonvulsant effect, the results are in favour of the usefulness of the model for antiabsence drugs." @default.
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- W2014218809 date "1991-06-01" @default.
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- W2014218809 title "Effect of psychotropic agents on a model of absence epilepsy in rats" @default.
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- W2014218809 doi "https://doi.org/10.1016/0028-3908(91)90086-q" @default.
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