Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014221639> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2014221639 endingPage "401" @default.
- W2014221639 startingPage "381" @default.
- W2014221639 abstract "Single ribosomal protein-16 S RNA complexes were examined for their sensitivity to trypsin digestion under conditions which maintain specific protein-RNA interactions. Proteins S7 and S13 are completely digested and removed from the complex while proteins S8, S15, S17 and S20 are protected from trypsin attack by the 16 S RNA. Protein S4 is partially protected yielding a fragment of a molecular weight of about 17,700. These results are in agreement with similar experiments done with different digestion conditions by Schulte et al. (1975). We have determined that the portion of protein S4 removed by the trypsin is the N-terminus up to residues 43 to 46. This conclusion is based on the following experimental results: (1) the tryptophan residue at position 167 remains a part of the S4 fragment after trypsin digestion; (2) the cysteine residue at position 31 is removed by trypsin digestion; (3) tryptide fingerprints indicate that the tyrosine at position 50 is not lost by trypsin digestion; (4) the loss of 4800 daltons is equivalent to approximately 44 amino acid residues. The role the N-terminus of protein S4 plays in ribosome assembly and function was investigated. Protein S4 fragment was mixed with 20 purified 30 S ribosomal proteins excluding protein S4 and reconstituted with 16 S RNA. An incomplete particle was produced. The proteins completely missing are S2, S10, S18 or S19 and S21. We postulate that these proteins interact either directly or indirectly with the N-terminal region of S4. Correlating this hypothesis with the electron microscopic results of Tischendorf et al. (1975), we also suggest that the N-terminus of protein S4 resides in the “head” region of the electron microscope model." @default.
- W2014221639 created "2016-06-24" @default.
- W2014221639 creator A5038321463 @default.
- W2014221639 creator A5050708250 @default.
- W2014221639 date "1976-12-01" @default.
- W2014221639 modified "2023-09-25" @default.
- W2014221639 title "The function of the N-terminal region of ribosomal protein S4" @default.
- W2014221639 cites W1487915912 @default.
- W2014221639 cites W1492288245 @default.
- W2014221639 cites W1524051883 @default.
- W2014221639 cites W1535514846 @default.
- W2014221639 cites W1564216598 @default.
- W2014221639 cites W2008848497 @default.
- W2014221639 cites W2010783126 @default.
- W2014221639 cites W2014860689 @default.
- W2014221639 cites W2017713471 @default.
- W2014221639 cites W2022685246 @default.
- W2014221639 cites W2029399437 @default.
- W2014221639 cites W2033750551 @default.
- W2014221639 cites W2038497321 @default.
- W2014221639 cites W2045877734 @default.
- W2014221639 cites W2046293760 @default.
- W2014221639 cites W2052063249 @default.
- W2014221639 cites W2056228115 @default.
- W2014221639 cites W2056747861 @default.
- W2014221639 cites W2074239242 @default.
- W2014221639 cites W2078278000 @default.
- W2014221639 cites W2091340753 @default.
- W2014221639 cites W2100837269 @default.
- W2014221639 cites W2133086465 @default.
- W2014221639 cites W2312483816 @default.
- W2014221639 cites W2313102356 @default.
- W2014221639 cites W2319048395 @default.
- W2014221639 cites W2320623144 @default.
- W2014221639 cites W2995464553 @default.
- W2014221639 doi "https://doi.org/10.1016/s0022-2836(76)80126-x" @default.
- W2014221639 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/796464" @default.
- W2014221639 hasPublicationYear "1976" @default.
- W2014221639 type Work @default.
- W2014221639 sameAs 2014221639 @default.
- W2014221639 citedByCount "37" @default.
- W2014221639 countsByYear W20142216392013 @default.
- W2014221639 countsByYear W20142216392014 @default.
- W2014221639 crossrefType "journal-article" @default.
- W2014221639 hasAuthorship W2014221639A5038321463 @default.
- W2014221639 hasAuthorship W2014221639A5050708250 @default.
- W2014221639 hasConcept C104317684 @default.
- W2014221639 hasConcept C153911025 @default.
- W2014221639 hasConcept C181199279 @default.
- W2014221639 hasConcept C185592680 @default.
- W2014221639 hasConcept C2779201268 @default.
- W2014221639 hasConcept C2780340462 @default.
- W2014221639 hasConcept C2781307694 @default.
- W2014221639 hasConcept C2781357212 @default.
- W2014221639 hasConcept C38062823 @default.
- W2014221639 hasConcept C43617362 @default.
- W2014221639 hasConcept C55493867 @default.
- W2014221639 hasConcept C67705224 @default.
- W2014221639 hasConcept C67905577 @default.
- W2014221639 hasConcept C86803240 @default.
- W2014221639 hasConcept C88478588 @default.
- W2014221639 hasConceptScore W2014221639C104317684 @default.
- W2014221639 hasConceptScore W2014221639C153911025 @default.
- W2014221639 hasConceptScore W2014221639C181199279 @default.
- W2014221639 hasConceptScore W2014221639C185592680 @default.
- W2014221639 hasConceptScore W2014221639C2779201268 @default.
- W2014221639 hasConceptScore W2014221639C2780340462 @default.
- W2014221639 hasConceptScore W2014221639C2781307694 @default.
- W2014221639 hasConceptScore W2014221639C2781357212 @default.
- W2014221639 hasConceptScore W2014221639C38062823 @default.
- W2014221639 hasConceptScore W2014221639C43617362 @default.
- W2014221639 hasConceptScore W2014221639C55493867 @default.
- W2014221639 hasConceptScore W2014221639C67705224 @default.
- W2014221639 hasConceptScore W2014221639C67905577 @default.
- W2014221639 hasConceptScore W2014221639C86803240 @default.
- W2014221639 hasConceptScore W2014221639C88478588 @default.
- W2014221639 hasIssue "2" @default.
- W2014221639 hasLocation W20142216391 @default.
- W2014221639 hasLocation W20142216392 @default.
- W2014221639 hasOpenAccess W2014221639 @default.
- W2014221639 hasPrimaryLocation W20142216391 @default.
- W2014221639 hasRelatedWork W1846734019 @default.
- W2014221639 hasRelatedWork W2004642669 @default.
- W2014221639 hasRelatedWork W2014932880 @default.
- W2014221639 hasRelatedWork W2023039516 @default.
- W2014221639 hasRelatedWork W2050544881 @default.
- W2014221639 hasRelatedWork W2057230030 @default.
- W2014221639 hasRelatedWork W2090173216 @default.
- W2014221639 hasRelatedWork W2099757697 @default.
- W2014221639 hasRelatedWork W2116246343 @default.
- W2014221639 hasRelatedWork W3206599079 @default.
- W2014221639 hasVolume "108" @default.
- W2014221639 isParatext "false" @default.
- W2014221639 isRetracted "false" @default.
- W2014221639 magId "2014221639" @default.
- W2014221639 workType "article" @default.